I am a molecular-cell biologist studying the genetic regulation of intestinal homeostasis in development and disease with the aim of identifying novel molecular targets for the treatment of disease and that can be validated in relevant preclinical mouse models.
I am a cancer molecular and cell biologist determining the mechanisms of anticancer drug action and resistance in both childhood and adult malignancies. My research involves the development and investigation of both in vivo and in vitro models of resistan
My basic science and translational research centres around elucidation of the function of the mucosal barrier in preventing infection, inflammation and development of cancers, and how defects in this barrier lead to these diseases.