Development of environmentally-friendly insecticides for the Australian livestock industry. Many insects and other arthropods are serious pests of Australian livestock. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use on pets and around the home and garden. Unfortunately, many of these arthropod pests have developed resistance to chemical insecticides. This aim of this re ....Development of environmentally-friendly insecticides for the Australian livestock industry. Many insects and other arthropods are serious pests of Australian livestock. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use on pets and around the home and garden. Unfortunately, many of these arthropod pests have developed resistance to chemical insecticides. This aim of this research program is to develop a new generation of environmentally-friendly natural products that can be used to control arthropod pests on farms and around the home and garden.Read moreRead less
Defining domains within Mycoplasma hyopneumoniae surface proteins that interact with host extracellular matrix: efficacy testing of candidate vaccines in swine. Over 90% of Australian commercial pig production facilities are affected by Mycoplasma hyopneumoniae, the causative agent of swine enzootic pneumonia. This disease causes economic losses in Australia of over $20 million per annum and up to $1 billion per annum in major swine rearing countries worldwide. This project will determine the p ....Defining domains within Mycoplasma hyopneumoniae surface proteins that interact with host extracellular matrix: efficacy testing of candidate vaccines in swine. Over 90% of Australian commercial pig production facilities are affected by Mycoplasma hyopneumoniae, the causative agent of swine enzootic pneumonia. This disease causes economic losses in Australia of over $20 million per annum and up to $1 billion per annum in major swine rearing countries worldwide. This project will determine the protective efficacy of new generation vaccines against M. hyopneumoniae, which aim to block the colonisation process and prevent disease .Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100441
Funder
Australian Research Council
Funding Amount
$474,443.00
Summary
Sounds of change: using ecological knowledge to advance acoustic monitoring. To recover biodiversity, conservation actions must be informed by robust ecological data. In partnership with Bush Heritage Australia, this project aims to transform ecological monitoring with eco-acoustic technologies by developing new acoustic metrics to measure biodiversity at various levels, from individual species through to whole communities. This project will combine advanced computer methods with theories of ani ....Sounds of change: using ecological knowledge to advance acoustic monitoring. To recover biodiversity, conservation actions must be informed by robust ecological data. In partnership with Bush Heritage Australia, this project aims to transform ecological monitoring with eco-acoustic technologies by developing new acoustic metrics to measure biodiversity at various levels, from individual species through to whole communities. This project will combine advanced computer methods with theories of animal sounds and communities to generate metrics that are informed by animal ecology and directly address monitoring needs of conservation organisations. By experimentally testing the metrics on long-duration real-world sound data, this project will provide new tools to measure conservation impact and prioritise actions.Read moreRead less
Peptidic spider toxins: a novel paradigm for control of insect pests. Many insects are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by insects are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, ....Peptidic spider toxins: a novel paradigm for control of insect pests. Many insects are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by insects are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, many of these insect pests have developed resistance to chemical insecticides. The aim of this research program is to develop a new generation of environmentally-friendly natural products and insect-resistant crops that can be used to control insect pests on farms and around the home and garden.Read moreRead less
This program will investigate the strategies used by pathogenic bacteria to cause human diseases. The research will focus on how bacteria initiate infections, how they invade, cause cell and tissue damage and respond to their human host. It will also examine how the host’s innate immune system interacts with these bacteria. The results will provide new insights into host-pathogen interactions and reveal new targets for the development of novel antibacterial drugs and vaccines.
New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput anal ....New antiparasitics to protect Australian livestock. There is an urgent need for new antiparasitics to treat multi-drug resistant livestock infections. This project aims to explore the bacteria and fungi present in the microbiomes of heavily infected sheep faeces and pastures, challenging them with environmental cues, including those from associated parasites, to stimulate production of defensive chemicals hidden deep within their genomes. Enabled by an integrated pipeline of high throughput analytical cultivation, molecular networking, and chemical and biological analyses, expected outcomes include an enhanced ability to explore and exploit valuable chemistry hidden within microbial genomes, leading to the discovery of new classes of natural antiparasitic to safeguard livestock.
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Orally active spider toxins: a novel paradigm for control of insect pests. Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ros ....Orally active spider toxins: a novel paradigm for control of insect pests. Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, many of these arthropod pests have developed resistance to chemical insecticides. This aim of this research program is to develop a new generation of environmentally-friendly natural products that can be used to control arthropod pests on pets, farms, and around the home and garden.Read moreRead less
Safeguarding Australia against invasive arthropod pests. An increasingly serious public health issue for Australia is the emergence of infectious diseases disseminated by arthropods such as ticks and mosquitoes. Arthropod-borne viruses are already the major human pathogens in Australia, and they disproportionately affect Aboriginal communities. The aim of this research is to develop environmentally-sustainable methods for controlling arthropods that destroy crops or disseminate human and animal ....Safeguarding Australia against invasive arthropod pests. An increasingly serious public health issue for Australia is the emergence of infectious diseases disseminated by arthropods such as ticks and mosquitoes. Arthropod-borne viruses are already the major human pathogens in Australia, and they disproportionately affect Aboriginal communities. The aim of this research is to develop environmentally-sustainable methods for controlling arthropods that destroy crops or disseminate human and animal disease. These insecticides will not only provide benefits within Australian territories, but will be useful to our defence forces when operating in overseas locations where arthropod pests are a problem (e.g., malarial regions of Iraq).Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101470
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
Improving poultry health and performance through microbiota manipulations. The project aims to develop methods to modulate microbiota to improve poultry health and productivity and reduce the need for antibiotics. Probiotic administration is currently the only way in agriculture to restore imbalanced intestinal microbiota. Recent research shows that intestinal microbiota resist all new-coming bacteria and remove them from the intestinal environment. The initial inoculum at the time of birth shap ....Improving poultry health and performance through microbiota manipulations. The project aims to develop methods to modulate microbiota to improve poultry health and productivity and reduce the need for antibiotics. Probiotic administration is currently the only way in agriculture to restore imbalanced intestinal microbiota. Recent research shows that intestinal microbiota resist all new-coming bacteria and remove them from the intestinal environment. The initial inoculum at the time of birth shapes the gut microbiota for life and has the strongest influence on development of the immune system. Accordingly, at-hatch administration of proven beneficial strains to poultry is likely to ensure permanent colonisation with beneficial bacteria. This process would improve both the productivity and health of poultry and other agricultural animals.Read moreRead less
Antiparastic agents to safeguard Australian livestock. This project will develop new and improved agrochemicals that can be used to treat highly multi-drug resistant parasites that infect Australian livestock, safeguarding animal health and welfare, and improving the economic viability and prosperity of the Australian livestock industry.