Discovery Early Career Researcher Award - Grant ID: DE240100502

Funder

Australian Research Council

Funding Amount

$424,875.00

Summary

Building Molecular Complexity Through Enzyme-Enabled Synthesis. Many valuable natural molecules are too complex to be commercially synthesised by current technologies. Despite advances in synthetic chemistry there is great need to adopt the elegant biocatalytic strategies for complex molecule synthesis found in nature, employing sophisticated enzyme catalysts. This interdisciplinary research program aims to address the shortcomings of traditional synthetic methods through the development of enzy .... Building Molecular Complexity Through Enzyme-Enabled Synthesis. Many valuable natural molecules are too complex to be commercially synthesised by current technologies. Despite advances in synthetic chemistry there is great need to adopt the elegant biocatalytic strategies for complex molecule synthesis found in nature, employing sophisticated enzyme catalysts. This interdisciplinary research program aims to address the shortcomings of traditional synthetic methods through the development of enzyme catalysts to rapidly generate complex molecular structures. These novel molecules can be readily converted into pharmaceuticals and agrochemicals leading to advancements in the bio-enabled production and application of organic molecules in these vital fields.
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