Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will re ....Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will resolve uncertainties in the underlying phenomena. The expected outcome should support future high quality cell cultures suitable for transplantation therapies.Read moreRead less
Empowering optical metamaterials with gain. Artificial materials composites (metamaterials) make it possible for us to observe extra-ordinary properties, such as magnetic behaviour in glass and bending light in any direction. The project proposes to enhance the usability of metamaterials by redesigning them to strengthen their interaction with light, thus making them suitable for industrial applications.
Discovery Early Career Researcher Award - Grant ID: DE170100821
Funder
Australian Research Council
Funding Amount
$381,000.00
Summary
Hyper-domain luminescence lifetime imaging for mapping molecular dynamics. This project aims to enable lifetime-multiplexed optical imaging of molecular dynamics of biological systems in real time. The grand challenge of modern life sciences is to understand the molecular origins of complex processes. Using lifetime measurement, this project will realise highly-multiplexed real-time luminescence imaging with simultaneous ultrahigh detection sensitivity and spatial resolution. By generating fresh ....Hyper-domain luminescence lifetime imaging for mapping molecular dynamics. This project aims to enable lifetime-multiplexed optical imaging of molecular dynamics of biological systems in real time. The grand challenge of modern life sciences is to understand the molecular origins of complex processes. Using lifetime measurement, this project will realise highly-multiplexed real-time luminescence imaging with simultaneous ultrahigh detection sensitivity and spatial resolution. By generating fresh insights into molecular fingerprints of relevance for future disease diagnostics and treatment, the project outcomes are expected to consolidate Australia’s leading position in the health sciences. Upon commercialisation, the intellectual property is expected to generate considerable economic returns.Read moreRead less
Non-invasive and safe human-machine interface (HMI) systems . This project aims to establish novel non-invasive human-machine interface systems based on multi-modal sensing and machine learning to intuitively command and control robotic and autonomous systems safely interacting and cooperating with humans. This will be achieved by harnessing the synergies across design optimisation, multi-modal sensing, additive manufacturing, machine learning, and assistive and cooperative robotic devices. Expe ....Non-invasive and safe human-machine interface (HMI) systems . This project aims to establish novel non-invasive human-machine interface systems based on multi-modal sensing and machine learning to intuitively command and control robotic and autonomous systems safely interacting and cooperating with humans. This will be achieved by harnessing the synergies across design optimisation, multi-modal sensing, additive manufacturing, machine learning, and assistive and cooperative robotic devices. Expected outcomes are a novel human-machine interface methodology, a new multi-purpose wearable data glove, and function and application-specific machine learning methods for cutting-edge applications in assistive robotic devices such as a prosthetic hand, advanced manufacturing, construction and agriculture.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100241
Funder
Australian Research Council
Funding Amount
$372,000.00
Summary
Seeing deeply inside the body with the world's smallest microscope. This project aims to develop the world's smallest in vivo microscope that can image the interior of living organisms at a subcellular resolution in a minimally invasive way. The project will shrink an entire microscope to the size of an optical fibre – as thin as a single strand of hair – and image deep regions of the central nervous system. This is expected to improve diagnostic tools and the knowledge of degenerative brain dis ....Seeing deeply inside the body with the world's smallest microscope. This project aims to develop the world's smallest in vivo microscope that can image the interior of living organisms at a subcellular resolution in a minimally invasive way. The project will shrink an entire microscope to the size of an optical fibre – as thin as a single strand of hair – and image deep regions of the central nervous system. This is expected to improve diagnostic tools and the knowledge of degenerative brain diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This project aims to completely transform the landscape of biomedical research and industry, with expected discoveries revolutionising the diagnosis and treatment of brain conditions.Read moreRead less
Making hydrogen storage work for the new hydrogen economy. This project aims to develop an innovative Liquid Organic Hydrogen Storage technology and prove its energy industry potential. This project expects to expand and validate the performance, safety and scale-up potential of this new technology in an industrial context to promote the development of the hydrogen economy. Expected outcomes include providing practical, efficient, large-scale storage technology for use in intermittent renewable ....Making hydrogen storage work for the new hydrogen economy. This project aims to develop an innovative Liquid Organic Hydrogen Storage technology and prove its energy industry potential. This project expects to expand and validate the performance, safety and scale-up potential of this new technology in an industrial context to promote the development of the hydrogen economy. Expected outcomes include providing practical, efficient, large-scale storage technology for use in intermittent renewable energy storage and hydrogen vehicle refuelling, and addressing legal/regulatory implementation issues. This should provide significant benefits in cultivating the emerging hydrogen energy industry, strengthening industrial competitiveness, enhancing Australia’s fuel security and protecting the environment.Read moreRead less
Bubble Dynamics in Fine Droplets: Behaviour and Control. The principal vision in this project is to gain a deeper understanding of the formation, growth and collapse of bubbles within micron-size droplets and, in doing so, provide the technical underpinning necessary to advance the development of a range of emerging technologies in the light alloys manufacturing, atomisation, non-invasive medical therapy, drug delivery, and nucleation / solidification in thermal energy storage systems. Expected ....Bubble Dynamics in Fine Droplets: Behaviour and Control. The principal vision in this project is to gain a deeper understanding of the formation, growth and collapse of bubbles within micron-size droplets and, in doing so, provide the technical underpinning necessary to advance the development of a range of emerging technologies in the light alloys manufacturing, atomisation, non-invasive medical therapy, drug delivery, and nucleation / solidification in thermal energy storage systems. Expected outcomes include new experimental evidence and validated mathematical models for the analysis of bubbles encapsulated by fine droplets. The outcomes should significantly enhance Australia’s research and innovation capacity in the field of confined space bubble dynamics and related industrial applications. Read moreRead less
Biologically Inspired Binaural Coupling for Selective Machine Hearing. This project aims to investigate biologically-inspired binaural coupling models in the context of the deep learning paradigm by formulating desirable higher level auditory structures as neural network sub-systems. This project expects to generate new knowledge for developing the next generation of robust speech processing systems that are capable of mimicking the selecting listening ability of humans when faced with realistic ....Biologically Inspired Binaural Coupling for Selective Machine Hearing. This project aims to investigate biologically-inspired binaural coupling models in the context of the deep learning paradigm by formulating desirable higher level auditory structures as neural network sub-systems. This project expects to generate new knowledge for developing the next generation of robust speech processing systems that are capable of mimicking the selecting listening ability of humans when faced with realistic noisy speech signals and the ‘cocktail party problem’ using innovative binaural feedback systems. This work should provide significant benefits, including improved voice biometrics and selective auditory attention capabilities in machines.Read moreRead less
Integrating biologically-inspired auditory models into deep learning. This project aims to discover how a biologically inspired auditory model can be tightly integrated into a state-of-the-art deep learning speech processing framework, to model, design and verify a deep learning based auditory model. Voice-based technologies, ranging from cochlear implants to smart homes, are growing at a rapid pace and speech interfaces are being integrated with all aspects of our lives. However, there is a gro ....Integrating biologically-inspired auditory models into deep learning. This project aims to discover how a biologically inspired auditory model can be tightly integrated into a state-of-the-art deep learning speech processing framework, to model, design and verify a deep learning based auditory model. Voice-based technologies, ranging from cochlear implants to smart homes, are growing at a rapid pace and speech interfaces are being integrated with all aspects of our lives. However, there is a growing demand to improve these voice-enabled services, making them more secure and less open to cyber-crime attack by unauthorised users. The project is expected to improve techniques for modelling and automatic processing of speech and audio signals, which should provide significant benefits, including improved voice biometrics and cochlear implants.Read moreRead less
Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a so ....Enhance ferromagnetic ordering by exchange coupling and defect engineering. This project aims to achieve room temperature ferromagnetism in two-dimensional materials via magnetic element doping and defect and interface engineering. Achieving high spin polarisation, high spin diffusion length and effective spin manipulation, the pre-requisites for functional spintronics devices, makes research into two-dimensional materials for spintronics applications difficult. This project could establish a solid foundation for realising qualified spintronics materials for spintronics devices. The expected outcomes are low power, high speed, spintronics devices, enhancing Australia’s strength in spintronics research.Read moreRead less