Identifying The Microbiological Risk Factors For Acute Lower Respiratory Infection In Indigenous Children To Inform Future Intervention Strategies
Funder
National Health and Medical Research Council
Funding Amount
$495,745.00
Summary
Lung infections such as pneumonia are common in Indigenous children, and can lead to repeated hospitalisation and permanent lung damage. They are also an important cause of preventable death in children. This study will look at the role of bacteria and viruses in lung infections, and will inform interventions to reduce the burden and consequences of lung infections in Indigenous children.
Intrinsic Host Antiviral Activity Against Pathogenic Filoviruses
Funder
National Health and Medical Research Council
Funding Amount
$488,754.00
Summary
Bats are a major reservoir for deadly human viruses including Ebola and Marburg virus. In contrast to humans, bats can be infected with these viruses without showing clinical signs of disease. The reason why bats can co-exist with these viruses is unknown. This study will determine if a bat antiviral molecule contributes to limiting virus release compared to the human version that could reveal strategies to prevent and control these deadly viruses in humans.
Electro-Optical Primers for Safe Use and Clean Manufacturing. Conventional primers contain a mechanically-sensitive primary explosive that is used to detonate the more stable propellant in a bullet. This project aims to address the health and environmental impacts of heavy metals in current primers by replacing them with benign, electrically or optically activated silicon-based materials. Modern semiconductor fabrication techniques will be used to develop safe and clean primers through cost-effe ....Electro-Optical Primers for Safe Use and Clean Manufacturing. Conventional primers contain a mechanically-sensitive primary explosive that is used to detonate the more stable propellant in a bullet. This project aims to address the health and environmental impacts of heavy metals in current primers by replacing them with benign, electrically or optically activated silicon-based materials. Modern semiconductor fabrication techniques will be used to develop safe and clean primers through cost-effective doping and deposition protocols. The expected outcomes of the project include a sovereign primer manufacturing capability for Australia. This will provide a significant strategic advantage and health benefits for law enforcement and defence personnel during live fire training and firing range exercises.Read moreRead less
Sensing and Communications for Tactical Radio: Mapping the RF Weather. This project investigates sensing, localisation and communication strategies to improve the performance of modern tactical radio networks. Such networks face all of the well-known design challenges of mobile ad-hoc networks (MANETs) but with added complication of a contested and adversarial operating environment. By exploiting the power of radio nodes to sense the radio spectrum, as well as to communicate over it, a distribut ....Sensing and Communications for Tactical Radio: Mapping the RF Weather. This project investigates sensing, localisation and communication strategies to improve the performance of modern tactical radio networks. Such networks face all of the well-known design challenges of mobile ad-hoc networks (MANETs) but with added complication of a contested and adversarial operating environment. By exploiting the power of radio nodes to sense the radio spectrum, as well as to communicate over it, a distributed network of nodes can create a detailed picture of the surrounding radio-frequency (RF) environment: the nodes can work together to map the “RF weather”. In this project we will design advanced sensing and localisation methods to accurately map the RF spectrum, and then exploit this map in communication system design.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101094
Funder
Australian Research Council
Funding Amount
$431,900.00
Summary
Energy absorption and impact mechanics of origami structures and materials. This project aims to understand the dynamic behaviour of origami structures and metamaterials by utilising interdisciplinary approaches. This project expects to generate new knowledge in the areas of origami engineering and structural mechanics. The success of this project will form a foundation for studying energy absorption and impact mechanics of origami family; the fundamental physics and mechanics will be applied to ....Energy absorption and impact mechanics of origami structures and materials. This project aims to understand the dynamic behaviour of origami structures and metamaterials by utilising interdisciplinary approaches. This project expects to generate new knowledge in the areas of origami engineering and structural mechanics. The success of this project will form a foundation for studying energy absorption and impact mechanics of origami family; the fundamental physics and mechanics will be applied to characterise microstructures and design novel metamaterials and offer a way of exploring new materials with superior and tuneable performance. This should provide significant benefits to improvement of their safety, stability and reliability performance in applications such as vehicles, warships and offshore engineering.Read moreRead less
Origami structures and materials: energy absorption and impact mechanics. This project will devise novel structures and advanced metamaterials to mitigate injury and death from impact or blast loading, using traditional origami folding concepts of design. This technology will have applications to many industries and occupations including vehicle manufacture and the military, as well as personal and public safety. Experiments and advanced numerical simulations will be performed and then analytica ....Origami structures and materials: energy absorption and impact mechanics. This project will devise novel structures and advanced metamaterials to mitigate injury and death from impact or blast loading, using traditional origami folding concepts of design. This technology will have applications to many industries and occupations including vehicle manufacture and the military, as well as personal and public safety. Experiments and advanced numerical simulations will be performed and then analytical models of structural plasticity and impact dynamics will be established to capture the physics involved. The findings will provide an insight into the fundamental mechanics of structures and metamaterials, as well as guidelines for their optimum design.Read moreRead less
Multilayered Safety Clothing for Personal Protective Equipment. This project aims to improve multilayered firefighting protective garments and their thermal comfort by utilizing aerogel microparticles containing thermal regulation materials and flame-retardant agents. This research will create new multifunctional fabric designs and engineering techniques to integrate improved heat and flame protection, comfort and smart features into optimized multilayered garments. It will create novel clothing ....Multilayered Safety Clothing for Personal Protective Equipment. This project aims to improve multilayered firefighting protective garments and their thermal comfort by utilizing aerogel microparticles containing thermal regulation materials and flame-retardant agents. This research will create new multifunctional fabric designs and engineering techniques to integrate improved heat and flame protection, comfort and smart features into optimized multilayered garments. It will create novel clothing systems that will better protect wearers and allow them to effectively combat bushfires and save lives and assets. The successful completion will enable industrial capability in next generation advanced protective garments and functional uniforms for broad occupational health safety and well-being applications.Read moreRead less
Intruder alert! detecting and classifying events in noisy time series. This project aims to address the mathematical challenges in automated early detection and classification of intrusion events in noisy time series generated from perimeter security systems. The project expects to develop robust methods to detect intrusion events under different operating environments while ignoring nuisance events. The project will boost the global competitiveness of the Australian security industry, and enabl ....Intruder alert! detecting and classifying events in noisy time series. This project aims to address the mathematical challenges in automated early detection and classification of intrusion events in noisy time series generated from perimeter security systems. The project expects to develop robust methods to detect intrusion events under different operating environments while ignoring nuisance events. The project will boost the global competitiveness of the Australian security industry, and enable improved event detection and classification in noisy time series to the benefit of many critical application areas beyond national security.Read moreRead less
The balance between cellular survival and death must be tightly regulated. Cells respond to viral infection by self-destructing, thus limiting viral spread to other cells. Viruses have evolved ways to subvert this defensive cell suicide. This project will define and characterise viral factors that maintain host cell survival during infection. These may be targets for the development of new anti-viral therapies and vaccines.
4D Printed Origami Structures: Deformation Mechanisms and Mechanics. This project aims to understand the physics and self-folding mechanisms of 4D printed origami structures and materials by utilising interdisciplinary approaches. This project expects to generate new knowledge in the areas of origami engineering and structural mechanics. The success of this project will form a foundation for studying shape-shifting and sequential control of smart origamis. The fundamental mechanics will be appli ....4D Printed Origami Structures: Deformation Mechanisms and Mechanics. This project aims to understand the physics and self-folding mechanisms of 4D printed origami structures and materials by utilising interdisciplinary approaches. This project expects to generate new knowledge in the areas of origami engineering and structural mechanics. The success of this project will form a foundation for studying shape-shifting and sequential control of smart origamis. The fundamental mechanics will be applied to characterise and design novel smart materials/structures with tuneable shape-morphing and mechanical performance. This should provide significant benefits to improvement of their safety, stability and reliability performance in applications such as space engineering, wearable technology and smart robotics.Read moreRead less