Centre Of Research Excellence In Infectious Diseases Modelling To Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$2,600,064.00
Summary
Infectious diseases pose a global challenge, with substantial human and economic costs. Mathematical models provide valuable frameworks to assess likely benefits of interventions to control infection spread and burden. Leveraging existing NHMRC support, we will expand modeling capability to inform infectious disease control policy in Australia and our region. Focus areas include vaccine preventable disease, respiratory viruses and emerging pathogens, supported by innovative methods development.
Assessment Of Interventions For Controlling Pandemic Influenza And Determining Data Needs To Inform These Assessments
Funder
National Health and Medical Research Council
Funding Amount
$183,040.00
Summary
The aim of this study is to help us prepare for a pandemic of influenza by comparing how effective the various available control strategies are at reducing transmission of the disease. The available control interventions include: reducing the number of close contacts we make with others, isolating cases after they are diagnosed, closing schools, quarantining households, quarantining individuals who are known to have been exposed to a case, and using antiviral drugs treat and protect people at ri ....The aim of this study is to help us prepare for a pandemic of influenza by comparing how effective the various available control strategies are at reducing transmission of the disease. The available control interventions include: reducing the number of close contacts we make with others, isolating cases after they are diagnosed, closing schools, quarantining households, quarantining individuals who are known to have been exposed to a case, and using antiviral drugs treat and protect people at risk of being infected. We will compare these control measures by taking due account of the ability and resources available for these interventions, and with regard to the need to maintain essential services. The comparisons will be made using mathematical models that describe the transmission of the infection. All available data and advice from experts will be used to ensure that realistic models are used for the comparisons. We will also use the models to determine the best use of the limited antiviral drugs available, until a vaccine becomes available. We will consider how the control strategy should be changed if a strain develops that is resistant to the antiviral drugs. In addition, we will determine what data need to be collected during the early stages of a pandemic to help us to determine the best use of the antiviral drugs, the best use of a new vaccine and to check on the development of resistance to the antiviral drugs.Read moreRead less
Fluid-structural interactions in high-speed flows. This project aims to perform experiments to measure fluid-structure interaction in hypersonic flows. The work will improve the accuracy of simulation tools that are urgently required to aid industry in the design of more structurally efficient and robust high-speed vehicles. These tools will in turn be used to reveal the underlying physics of the fluid-structure interactions and establish the relative significance of the driving parameters. Accu ....Fluid-structural interactions in high-speed flows. This project aims to perform experiments to measure fluid-structure interaction in hypersonic flows. The work will improve the accuracy of simulation tools that are urgently required to aid industry in the design of more structurally efficient and robust high-speed vehicles. These tools will in turn be used to reveal the underlying physics of the fluid-structure interactions and establish the relative significance of the driving parameters. Accurate prediction of the behaviour and lifetime of structural components subject to these fluid-structural interactions, in which the deformation of the structure induced by the local flow field, can in turn influence this flow field. This coupling can result in damage or even catastrophic structural failure and thus robust design tools must be developed to avoid this.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100133
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
National Facility for Physical Blast Simulation (NFPBS). Recent terrorist attacks employing large quantities of high explosives have prompted the international demand for experimental investigation of civil infrastructure response to shock wave loadings. The National Facility for Physical Blast Simulation (NFPBS) is one of only a few in the world that are suitable for conducting experimental research via a physically generated blast approach.
A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing ....A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing pad which can be used as the next generation combat helmet liners and accessories. The novel high-performance energy absorption system will have a wide range of direct applications in future personal armour, as well as sports gears and elderly healthcare products.Read moreRead less
Human-Unmanned Aerial Vehicle interactions: Making drones talk and listen. This project aims to develop audio technology to enable unmanned aerial vehicles or drones to hear, use speech and sound to communicate with humans, acoustically sense their surroundings and make them less noisy. This project expects to generate new knowledge in acoustic signal processing and its application in drones using innovative approaches, such as use of miniature microphone and loudspeaker arrays, and active noise ....Human-Unmanned Aerial Vehicle interactions: Making drones talk and listen. This project aims to develop audio technology to enable unmanned aerial vehicles or drones to hear, use speech and sound to communicate with humans, acoustically sense their surroundings and make them less noisy. This project expects to generate new knowledge in acoustic signal processing and its application in drones using innovative approaches, such as use of miniature microphone and loudspeaker arrays, and active noise control. Expected outcomes include development of new theories, Intellectual Property, with potential commercial value, and training of next generation researchers. This should provide significant benefits with applications in life saving, search and rescue operations, transportation of goods, and creation of 3D media.Read moreRead less
Intriguing aerodynamics of bees, hoverflies and beyond. Nature observers have long been fascinated by the elegance, agility and endurance of flying insects, but still human-engineered vehicles fail to match their performance. This project aims to reveal the key physical aspects that allow two different insects to fly so well and thus unlock greater performance for flapping flight vehicles beyond insects.
Nonlinear topological photonics . The rapidly growing demands of information processing have launched a race for compact optical devices transmitting signals without losses. Topological phases of light provides unique opportunities to create new photonic systems with functionalities and efficiencies well beyond current capabilities. This project aims to develop new ways to generate and guide light at the nanoscale by merging fundamental concepts of nonlinear photonics and topological physics. Th ....Nonlinear topological photonics . The rapidly growing demands of information processing have launched a race for compact optical devices transmitting signals without losses. Topological phases of light provides unique opportunities to create new photonic systems with functionalities and efficiencies well beyond current capabilities. This project aims to develop new ways to generate and guide light at the nanoscale by merging fundamental concepts of nonlinear photonics and topological physics. The outcomes of this project will result in experimental demonstration of the world-first, highly efficient, compact, and lossless nonlinear photonic devices for advanced optical technologies.Read moreRead less
Electron Transpiration Cooling of Hypersonic Vehicles. Future aircraft for flight at hypersonic speeds require sharp leading edges for the best aerodynamic performance. Sharp leading edges incur high heat loads and cannot be adequately cooled with current technologies. The project aim is to investigate novel surface materials that emit electrons when heated. This emission of electrons from the surface can significantly contribute to the cooling of the sharp leading edges. This project is expecte ....Electron Transpiration Cooling of Hypersonic Vehicles. Future aircraft for flight at hypersonic speeds require sharp leading edges for the best aerodynamic performance. Sharp leading edges incur high heat loads and cannot be adequately cooled with current technologies. The project aim is to investigate novel surface materials that emit electrons when heated. This emission of electrons from the surface can significantly contribute to the cooling of the sharp leading edges. This project is expected to deliver new experimental data on novel surface materials exposed to a hypersonic flow environment and computer models that can simulate their cooling effect. This investigation will contribute towards enabling technologies for sustained hypersonic flight by overcoming critical head load limitations.Read moreRead less
Emerging technologies of warfare as a challenge to the law of armed conflict: cyber-attacks, robotics and nanotechnology. In order to reduce suffering in war, international law places limits on the ways in which the adversary can be harmed. This project will assess how the law fares in dealing with emerging technologies, such as hostile uses of computer networks, robotics and nanotechnology. It will provide guidance to policy makers on how the law can be improved.