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The role of community music in addressing social inequalities in Australia. This project aims to investigate the role community music can play in addressing social inequalities in Australia. The research expects to map and analyse a range of social outcomes fostered by community music, and investigate how these outcomes can enrich current place-based efforts to address social disadvantage. Through national sector mapping, community case studies, and an innovative analytic framework, expected out ....The role of community music in addressing social inequalities in Australia. This project aims to investigate the role community music can play in addressing social inequalities in Australia. The research expects to map and analyse a range of social outcomes fostered by community music, and investigate how these outcomes can enrich current place-based efforts to address social disadvantage. Through national sector mapping, community case studies, and an innovative analytic framework, expected outcomes include new interdisciplinary knowledge, music and social sector development, and greater creativity in place-based policies tackling inequalities. This should provide significant benefits for Australian communities where social inequalities exist, by harnessing their creative assets to drive positive social change. Read moreRead less
Codesigning processes to improve technology service provision for aged care. This research investigates the learning and implementation of novel technologies applying a participatory approach with aged care residents. In partnership with Martin Luther Homes (a not-for-profit aged care provider) and The Brainary (an educational technology provider), we will co-design recommendations and innovative services that are necessary to enable strategic planning and technology uptake of residents. We cre ....Codesigning processes to improve technology service provision for aged care. This research investigates the learning and implementation of novel technologies applying a participatory approach with aged care residents. In partnership with Martin Luther Homes (a not-for-profit aged care provider) and The Brainary (an educational technology provider), we will co-design recommendations and innovative services that are necessary to enable strategic planning and technology uptake of residents. We create value through the shared goal orientation bringing use of technology in aged care and business together as a service. Co-creating processes exploring technologies with older adults will translate into residents receiving the support they need. We can expect to achieve better quality of care and equity in technology use. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210101137
Funder
Australian Research Council
Funding Amount
$458,665.00
Summary
Exploiting biological noise for next generation electrochemical biosensors. This project aims to harness the intrinsic noise in a biological system to develop a new platform for biosensors. This will lead to advancement of a new versatile electrochemical platform for real-time screening with vast applications that span from sensing at sub-cellular level to point-of-care and implantable biosensors. The new sensory technique will improve the specificity, sensitivity and resolution in biosensors an ....Exploiting biological noise for next generation electrochemical biosensors. This project aims to harness the intrinsic noise in a biological system to develop a new platform for biosensors. This will lead to advancement of a new versatile electrochemical platform for real-time screening with vast applications that span from sensing at sub-cellular level to point-of-care and implantable biosensors. The new sensory technique will improve the specificity, sensitivity and resolution in biosensors and enables measurement of multiple biomarkers simultaneously in real-time. The outcomes will contribute to a better understanding of fundamental physiological processes and chemical interactions at subcellular level which will inform future advancements in biomedical engineering.
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Discovery Early Career Researcher Award - Grant ID: DE240100095
Funder
Australian Research Council
Funding Amount
$378,920.00
Summary
Using systems science to secure the health workforce against climate change. The widespread maldistribution of the Australian health workforce is creating significant health human resource shortages in non-urban areas of need. Climate-related extreme weather events (i.e., heat, droughts, fires, floods) are projected to exacerbate workforce deficiencies in rural regions. This project aims to explore how climate change will impact the future of the rural health workforce through a novel integratio ....Using systems science to secure the health workforce against climate change. The widespread maldistribution of the Australian health workforce is creating significant health human resource shortages in non-urban areas of need. Climate-related extreme weather events (i.e., heat, droughts, fires, floods) are projected to exacerbate workforce deficiencies in rural regions. This project aims to explore how climate change will impact the future of the rural health workforce through a novel integration of computational systems science methods. The project expects to discover new policies to correct the maldistribution and strengthen the resilience of the rural health workforce against climate change impacts. Benefits include a sustained and more adaptable workforce leading to improved health for vulnerable communities.Read moreRead less
The “New” Biochemistry of Polyamines: When Metabolic Pathways Collide. Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyami ....The “New” Biochemistry of Polyamines: When Metabolic Pathways Collide. Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyamines, as we have discovered that polyamines are regulated by iron at 2-major levels, involving >10-key polyamine pathway proteins. This proposal represents first-in-field studies specifically designed to dissect mechanisms involved in this relationship. Our Central Hypothesis is that iron regulates polyamine metabolism.Read moreRead less
A novel platform-technology for long-term subcutaneous neurophysiology. This project aims to develop a novel miniature device for subcutaneous and tetherless brain sensing. It addresses the lack of a device solution for brain-sensing that combines ultra-long-term reliable sensing capability and small dimensions for minimally-invasive procedures. We achieve this through our novel electrode architecture that significantly enhances the quality and reliability of recorded brain signals. We introduce ....A novel platform-technology for long-term subcutaneous neurophysiology. This project aims to develop a novel miniature device for subcutaneous and tetherless brain sensing. It addresses the lack of a device solution for brain-sensing that combines ultra-long-term reliable sensing capability and small dimensions for minimally-invasive procedures. We achieve this through our novel electrode architecture that significantly enhances the quality and reliability of recorded brain signals. We introduce a platform technology designed for subscalp anatomy with future use in various brain-machine interfacing applications relying on reliable, long-term and easy-to-implant systems. This project's device manufacturing, training, and intellectual property are expected to strengthen Australia's position in bioelectronics.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
Diamond Microneedles for Minimally Invasive Blood Collection. Blood sampling is a routine procedure for medical purposes to determine the physiological and biochemical status of patients. The aim of this project is to develop a reliable microneedle array for a blood collection procedures. Micro-scale needles for low-volume perforated blood samples are highly desirable due to its minimal invasiveness and painlessness. The miniaturization of sampling platforms driven by microneedles has the poten ....Diamond Microneedles for Minimally Invasive Blood Collection. Blood sampling is a routine procedure for medical purposes to determine the physiological and biochemical status of patients. The aim of this project is to develop a reliable microneedle array for a blood collection procedures. Micro-scale needles for low-volume perforated blood samples are highly desirable due to its minimal invasiveness and painlessness. The miniaturization of sampling platforms driven by microneedles has the potential to shift disease diagnosis and monitoring closer to the point of care. Expected outcomes include the development of synthetic diamond-based microneedles for the potential to greatly benefit society through improved and affordable healthcare and the development of new high-tech industries.Read moreRead less
Biophysics-informed deep learning framework for magnetic resonance imaging. This project aims to bring about a paradigm shift from the conventional non-quantitative magnetic resonance imaging to ultra-fast, quantitative, and artefact free imaging. This project integrates biophysics and artificial intelligence, and it is expected to bring new knowledge in both fields. The expected outcomes of this project include next generation magnetic resonance imaging methods with a fundamental shift in the ....Biophysics-informed deep learning framework for magnetic resonance imaging. This project aims to bring about a paradigm shift from the conventional non-quantitative magnetic resonance imaging to ultra-fast, quantitative, and artefact free imaging. This project integrates biophysics and artificial intelligence, and it is expected to bring new knowledge in both fields. The expected outcomes of this project include next generation magnetic resonance imaging methods with a fundamental shift in the approach to image artefacts and image quantification. This project is expected to advance both single subject and population level biomedical imaging with greater accuracy and cost-effectiveness. This project also promotes explainable and generalisable artificial intelligence in medical imaging.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100235
Funder
Australian Research Council
Funding Amount
$422,241.00
Summary
The impact of mass gathering events on emergency healthcare services. Mass gathering events (MGEs) occur frequently across Australia. The preparation of a MGE from an emergency healthcare service perspective is conducted with limited evidence to support decision-making. Using routinely collected data from Tourism and Events Queensland, Queensland Ambulance Service, Queensland Emergency Departments, and the Bureau of Meteorology, this research aims to determine the impact on ambulance and emergen ....The impact of mass gathering events on emergency healthcare services. Mass gathering events (MGEs) occur frequently across Australia. The preparation of a MGE from an emergency healthcare service perspective is conducted with limited evidence to support decision-making. Using routinely collected data from Tourism and Events Queensland, Queensland Ambulance Service, Queensland Emergency Departments, and the Bureau of Meteorology, this research aims to determine the impact on ambulance and emergency department services in the vicinity of 750 planned MGEs over a five year period (2015 - 2019). The expected outcome includes an enhanced ability to predict the required emergency healthcare services for a MGE, therefore enhancing the planning and response, benefiting MGE attendees and the MGE host community.Read moreRead less