Use Of Expression Profiling To Identify Genes Influencing Cardiovascular Risk In The Norfolk Island Population Isolate
Funder
National Health and Medical Research Council
Funding Amount
$697,409.00
Summary
This study will use a unique population isolate from Norfolk Island. We aim to identify genes that play a role in cardiovascular disease risk. Norfolk has a population of ~1200 permanent residents, most of whom are direct descendents of 18th century English Bounty mutineers and Polynesian women. We will undertake gene expression mapping to identify genomic loci that influence cardiovascular disease using samples from this population isolate.
Structural Basis For Inhibition Of Malaria Invasion By Targeting The Apical Membrane Antigen Of Plasmodium Falciparum.
Funder
National Health and Medical Research Council
Funding Amount
$434,134.00
Summary
3 million children die every year from malaria infections. A leading vaccine candidate is a protein from the malaria parasite called AMA1. Humans that have been infected with malaria make antibodies to this protein which can kill parasites, however little is known about how this occurs. We aim to identify regions of the protein that generate antibodies that prevent malaria parasites from invading human cells and help in the search for a vaccine against malaria.
Improved design and control of brushless doubly-fed reluctance machine generators for wind power applications. The growing importance of the reduction in greenhouse gas emissions over the coming years is driving the increased usage of renewable energy sources such as wind power. Currently the cost of wind energy is considerably higher than fossil fuel energy sources. Part of the reason for this is the initial cost and ongoing maintenance of the wind turbines. The proposed research considers a n ....Improved design and control of brushless doubly-fed reluctance machine generators for wind power applications. The growing importance of the reduction in greenhouse gas emissions over the coming years is driving the increased usage of renewable energy sources such as wind power. Currently the cost of wind energy is considerably higher than fossil fuel energy sources. Part of the reason for this is the initial cost and ongoing maintenance of the wind turbines. The proposed research considers a new kind of generator based on the Brushless Doubly Fed Machine (BDFRM) that has the potential to lower the initial cost of the generator/inverter hardware of the wind turbine, and also decrease the ongoing maintenance costs. If the research is able to show that the BDFRM is able to realise its potential, then this will aid the further use of wind energy.Read moreRead less
A high performance, robust and sensorless Natural Field Oriented controller for induction machine drives. Natural Field Orientation (NFO) is a technique of field oriented control of AC machines that is potentially very robust, able to operate at low speeds, and inherently sensorless. However, it is a little known fact that under regenerative conditions the algorithm is unstable. The primary aim of this project is to develop a NFO algorithm that is stable under regeneration, and has minimum depen ....A high performance, robust and sensorless Natural Field Oriented controller for induction machine drives. Natural Field Orientation (NFO) is a technique of field oriented control of AC machines that is potentially very robust, able to operate at low speeds, and inherently sensorless. However, it is a little known fact that under regenerative conditions the algorithm is unstable. The primary aim of this project is to develop a NFO algorithm that is stable under regeneration, and has minimum dependence on machine parameters. If these aims are achieved the NFO algorithm would be a significant addition to control algorithms for AC machines, allowing their use in a broader range of applications.
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