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Developing An Australian Valuation For The EQ-5D-5L Quality Of Life Instrument
Funder
National Health and Medical Research Council
Funding Amount
$348,357.00
Summary
In the assessment of gains resulting from a health technology, it is standard to consider both mortality and quality of life effects. This project explores how Australians value different components of quality of life. To do this, we are running an online survey called a discrete choice experiment, and analysing the data using a range of cutting-edge econometric techniques. This will allow policy-makers to better reflect people's preferences when making decisions about new technologies.
Measuring Health Related Social Preferences And Their Inclusion In An Alternative Method For Prioritising Health Services
Funder
National Health and Medical Research Council
Funding Amount
$430,143.00
Summary
The project measures the public preference for sharing the health budget rather than maximising average health. It quantifies the importance of severity, patient age and health potential and illustrates an alternative criterion to the maximisation of cost effectiveness for the allocation of the health budget.
Sedation Practice In Intensive Care Evaluation (SPICE) Randomised Controlled Trial.
Funder
National Health and Medical Research Council
Funding Amount
$2,752,725.00
Summary
Almost every patient in intensive care needs sedating drugs for comfort and provision of life-saving treatment. However, sedation causes side effects including coma, delirium and agitation. There is no high-level evidence to help doctors decide which sedatives to choose and the best way to administer them. The SPICE trial will test a new approach called Early Goal-Directed Sedation based on an alternative sedative agent to see whether it delivers safer, targeted light sedation with less delirium ....Almost every patient in intensive care needs sedating drugs for comfort and provision of life-saving treatment. However, sedation causes side effects including coma, delirium and agitation. There is no high-level evidence to help doctors decide which sedatives to choose and the best way to administer them. The SPICE trial will test a new approach called Early Goal-Directed Sedation based on an alternative sedative agent to see whether it delivers safer, targeted light sedation with less delirium.Read moreRead less
Economic Evaluation Of Alternative Pneumococcal Vaccination Strategies
Funder
National Health and Medical Research Council
Funding Amount
$242,894.00
Summary
Pneumococcal vaccination is a readily available preventive strategy that can offer substantial protection to the elderly but it is important that we carefully evaluate the different potential strategies to ensure the most (cost-) effective approach to prevention is identified. This grant will explore alternative strategies to control pneumococcal-related disease in elderly Australians using the available vaccines.
Increasing Population Health By Making Better Funding Decisions: Estimation Of The Cost-effectiveness Threshold For The Australian Health System
Funder
National Health and Medical Research Council
Funding Amount
$341,368.00
Summary
This project will estimate the Australian opportunity cost of decisions to fund new health care technologies, such as pharmaceuticals and medical devices. The opportunity cost represents the health benefits that could be achieved if the resources used to fund a new technology are used to fund the best alternative technology or service instead. We will then disseminate the information to decision makers, to improve funding decisions, and hence the efficiency of the Australian health care system.
Is Highly-sensitive Troponin Testing Advancing Clinical Practice, Improving Outcomes And Cost-effective In The Investigation And Management Of Chest Pain In The Emergency Department?
Funder
National Health and Medical Research Council
Funding Amount
$1,193,966.00
Summary
Expensive next generation blood tests offer the promise of more efficient detection of heart muscle damage in people with chest pain presenting to the Emergency Department. We aim to evaluate the treatment, management, cost and outcome at 1 year before and after these new blood tests were introduced in a national multi-hospital study.
Using An Established Simulation Model To Determine Effective And Cost-effective Interventions To Mitigate Influenza Pandemics And Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$416,353.00
Summary
A novel disease spread and economic model is used to determine the cost-effectiveness of a range of mitigation strategies aimed at a future influenza pandemic. A simulation model generates data on which individuals become ill, morbidity and mortality characteristics, an economic costing model determines optimal interventions.
Development And Validation Of A Health Policy Simulation Model For Type 1 Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$409,199.00
Summary
This proposal brings together an international multi-disciplinary team to develop and validate a health economic computer simulation model for type 1 diabetes and its complications. It examines the impact of diabetes on costs as well as quality of life. Outcomes generated by the model will inform health policy decisions regarding allocation of resources for people with type 1 diabetes such as cost-effectiveness analysis of new treatments and technologies.
A Multi-Centre Double-Blind Randomised Placebo-Controlled Trial Of Oral Anticoagulation In Systemic Sclerosis-Related Pulmonary Arterial Hypertension
Funder
National Health and Medical Research Council
Funding Amount
$1,190,521.00
Summary
Scleroderma is an autoimmune disease that shortens life span by over 30 years. The main cause of death is pulmonary arterial hypertension (PAH), a condition of increased pressure in the lung vessels. Even in the era of 'advanced' PAH therapy, only 50% of patients are alive beyond 5 years. Formation of clots in the small blood vessels of the lung plays a major role in the development of PAH. In this clinical trial we aim to determine whether anticoagulation (treatment to prevent clotting) improve ....Scleroderma is an autoimmune disease that shortens life span by over 30 years. The main cause of death is pulmonary arterial hypertension (PAH), a condition of increased pressure in the lung vessels. Even in the era of 'advanced' PAH therapy, only 50% of patients are alive beyond 5 years. Formation of clots in the small blood vessels of the lung plays a major role in the development of PAH. In this clinical trial we aim to determine whether anticoagulation (treatment to prevent clotting) improves survival in scleroderma PAH.Read moreRead less
The Out-and-About Trial: Improving Quality Of Life By Increasing Outdoor Journeys After Stroke
Funder
National Health and Medical Research Council
Funding Amount
$586,009.00
Summary
Many stroke patients cannot walk well when they leave hospital nor use public transport. Escorted outdoor journeys with a rehabilitation therapist can improve outcomes and quality of life after stroke. Yet not many stroke patients do not receive this type of community rehabilitation. This project aims to evaluate an implementation program to change therapists' practice and increase outdoor journeys after stroke. Benefits include improved quality of life and well being for peope with stroke.