Understanding Human Dysmorphology Through Analysis Of ENU Mutant Mice
Funder
National Health and Medical Research Council
Funding Amount
$602,501.00
Summary
Birth defects are common and have an enormous impact on both the individual and their family. Birth defects are by definition the products of abnormal development of the embryo. Our research is aimed at identifying the normal mechanisms that usually prevail during development and the disturbances to those mechanisms that result in birth defects. These findings will lead to improved diagnostic, therapeutic and preventative options for families affected by birth defects
Rapid Identification And Characterisation Of Genes Involved In Skeletal Development
Funder
National Health and Medical Research Council
Funding Amount
$550,536.00
Summary
Birth defects are common and have an enormous impact on both the individual and their family. Birth defects are by definition the products of abnormal development of the embryo. Our research is aimed at identifying the normal mechanisms that usually prevail during development and the disturbances to those mechanisms that result in birth defects. These findings will lead to improved diagnostic, therapeutic and preventative options for families affected by birth defects
Migratory Cells To Ganglionated Network: Self-organization Of The Enteric Nervous System
Funder
National Health and Medical Research Council
Funding Amount
$328,294.00
Summary
The intestine has its own nervous system. This develops from cells that wander into the intestine during early development and self-organize to form the functional nervous system . The correct organization of the cells of this nervous system is required for correct intestine function. How they self-organize is not known, and there are diseases in which the process is disturbed. Molecular and cell biology and mathematical modelling will be used to understand how this occurs.