Novel Interventions To Address Methamphetamines In Aboriginal Communities, Including A Randomised Trial Of A Web Based Therapeutic Tool Used To Treat Dependence In Clinical Settings.
Funder
National Health and Medical Research Council
Funding Amount
$2,177,908.00
Summary
Methamphetamine use in Aboriginal communities has gained much media attention, despite limited research studies to ascertain the full extent of its use and its impact. We propose a randomised trial of a web based therapeutic tool for use in Aboriginal Medical Services to treat clients using methamphetamines. In addition we will characterise the health and well-being of Aboriginal people who use methamphetamines and trial unique Aboriginal community led interventions to address methamphetamines.
Preventing Anxiety, Depression And Substance Use In Adolescents.
Funder
National Health and Medical Research Council
Funding Amount
$1,709,988.00
Summary
Anxiety, depressive and substance use disorders account for three quarters of the disability attributed to mental disorders. Yet we have few models of well-implemented prevention programs for these common disorders. The current proposal addresses this gap by evaluating an innovative internet-based approach to preventing mental health and substance use problems in Australian adolescents.
An Investigation Of The Involvement Of Clotting Factors In Abdominal Aortic Aneurysm (AAA) Progression Within A Mouse Model
Funder
National Health and Medical Research Council
Funding Amount
$189,401.00
Summary
Early stage weakening of the main abdominal artery is present in ~100,000 Australians and currently has no accepted therapy. Development of drug therapies which limit progression of the weakening process is urgently needed. In this study involvement of the clotting cascade in artery weakening will be investigated. The study have been planned in order to identify new strategies which can be developed as treatments for artery weakening in patients.
Indigenous Mental Health Model Of Care: RCT Based On A Trans-diagnostic CBT Program Co-designed With Community
Funder
National Health and Medical Research Council
Funding Amount
$996,217.00
Summary
We propose to develop an Indigenous Model of Mental Health Care (IMMHC) that encompasses psychological therapy and cultural healing practices developed in consultation with local, participating Indigenous communities, that will for the first time treat highly prevalent mood and anxiety disorders in Indigenous Australians.
Use Of Molecular Resistance Assays To Provide Alterative Oral Treatment Strategies For Gonorrhoea In Indigenous And Other High-risk Populations; A Randomised Cluster Trial
Funder
National Health and Medical Research Council
Funding Amount
$828,671.00
Summary
Gonorrhoea has now developed resistance to almost all antibiotics that have been used to treat it. In this study, we will investigate a new treatment approach that selects antibiotics on a patient-by-patient basis. We will use new molecular assays to first test if a gonorrhoea strain infecting a patient is susceptible to an antibiotic, and will then treat on the basis of this result. By doing so, we will optimize our use of antibiotics and improve treatment strategies for gonorrhea.
A Pragmatic Randomised Clinical Trial Of Nicotine Vaporisers Added To Smoking Cessation Treatment For Priority Populations Living With Comorbidities
Funder
National Health and Medical Research Council
Funding Amount
$1,499,145.00
Summary
Smoking is a leading cause of early death for people with certain health conditions because they are more likely to smoke and are also at greater risk of tobacco-related disease. This clinical trial will test whether encouraging people living with Hepatitis C Virus, people on opiate substitution therapy and people living with HIV who smoke to use nicotine vaporisers long-term, in addition to current smoking cessation treatments, will help them to stay abstinent from smoking.
Transitions of mobility and parking. Transitions of mobility and parking. This project aims to understand the role of parking in mobility, urban consolidation and transit-oriented development. Does parking supply affect travel demand, car ownership, and ultimately urban quality of life? New transitions and trends in land-use and transport, including car-sharing and automated vehicles, and the revival of urban living, raise important questions about the redesign and reuse of urban space. This pro ....Transitions of mobility and parking. Transitions of mobility and parking. This project aims to understand the role of parking in mobility, urban consolidation and transit-oriented development. Does parking supply affect travel demand, car ownership, and ultimately urban quality of life? New transitions and trends in land-use and transport, including car-sharing and automated vehicles, and the revival of urban living, raise important questions about the redesign and reuse of urban space. This project aims to give policy-makers an evidence base and toolkit to determine how best to repurpose the space currently accommodating private cars. This project is expected to make cities more attractive, efficient and liveable, improving a disproportionately large number of Australian lives.Read moreRead less
Who You Know or Where You Go? The Role of Formal and Informal Networks in Finding Employment and Maintaining Wellbeing. Recent empirical studies have demonstrated that informal social networks improve well-being and labour market outcomes for the unemployed in Europe. However, no comparable Australian study has been conducted and there is little research on the role of the 'formal' networks represented by employment services programs in Australia or overseas. This project aims to explore unemplo ....Who You Know or Where You Go? The Role of Formal and Informal Networks in Finding Employment and Maintaining Wellbeing. Recent empirical studies have demonstrated that informal social networks improve well-being and labour market outcomes for the unemployed in Europe. However, no comparable Australian study has been conducted and there is little research on the role of the 'formal' networks represented by employment services programs in Australia or overseas. This project aims to explore unemployed people's formal and informal networks and the impact of those networks on employment status and wellbeing. This project aims to inform unemployment policy design and service delivery by providing a greater understanding of the role that social networks play in finding jobs and surviving unemployment.Read moreRead less
Antibiotic resistance is a looming public health crisis. New antibiotics with new mechanisms of action are desperately needed. The long-term goal of this research is to develop new drugs that disarm bacteria to overcome the problem of antibiotic resistance.
Immuno-polymeric Drugs For Prostate Cancer Therapy
Funder
National Health and Medical Research Council
Funding Amount
$626,995.00
Summary
Prostate cancer is the most common cancer in men over 50 and the second most frequent cause of cancer deaths in Western society. Docetaxel is the first line of chemotherapy when other intervention strategies are unsuccessful, but 30% of patients suffer from severe side-effects. To address this problem, we will utilise carriers for docetaxel that directly target prostate tumours using a novel antibody approach. This increases accumulation at the tumour site while decreasing off-target toxicity.