Control Of Organ Size During Development And Disease By The Salvadore-Warts-Hippo Pathway
Funder
National Health and Medical Research Council
Funding Amount
$331,674.00
Summary
Cancer is a disease that results from the generation of too many cells. Many signalling pathways control cell number including the newly identified Salvador-Warts-Hippo pathway. We are studying the mechanisms by which activity of this pathway is controlled, using the vinegar fly as a model. Information obtained from our study will aid understanding of human cancer as cellular processes which go awry in cancer, such as cell proliferation and death, are highly conserved between flies and humans.