Snail Family Proteins Regulate Stem Cell Differentiation
Funder
National Health and Medical Research Council
Funding Amount
$288,650.00
Summary
This research aims to discover the role of a family of genes in regulating stem cells. These genes are known to turn other genes off and we have shown that this family is required to maintain stem cells in animal tissues. The current research seeks to determine which genes are normally switched off in order to maintain normal stem cells. We also aim to determine if turning these genes on leads to cancer formation.
Mechanisms Regulating The Levels Of Circulating Insulin In Response To Nutrition
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Diabetes is the fastest growing chronic disease both in Australia and worldwide, caused by the failure of cells within the pancreas to produce sufficient insulin. I aim to determine how different nutritional inputs alter the levels of circulating insulin, and identify and characterise genes required for insulin production and secretion. As well as providing important insights into the mechanisms that regulate insulin secretion, I will identify new therapeutic targets for diabetes treatment.