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Novel Signalling Pathways Leading To The Activation Of Glomerular Parietal Epithelial Cells
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
Chronic kidney disease (CKD) is a major health problem in Australia. CKD patients have very limited therapeutic options. The majority of diseases that lead to CKD are associated scarring of the renal filters. Parietal epithelial cells reside in these filters and play key roles in scarring development. However, the molecular mechanisms that lead to scarring in these renal filters remain unclear. This proposal aims to identify molecular pathways that may serve as future therapeutic targets.
IMPROVING THE FOOD SUPPLY TO REDUCE THE BURDEN OF NUTRITION-RELATED CHRONIC DISEASE
Funder
National Health and Medical Research Council
Funding Amount
$338,945.00
Summary
My project will examine the healthiness of the Australian food supply with the goal of identifying where reformulation activities will have the greatest impact on the health of Australians. The results will be used to inform policies designed to enhance the healthiness of the food supply, and will make a significant contribution to the understanding of dietary intake and the food supply in Australia, and will help reduce the ever-increasing burden of nutrition-related chronic disease.
Improving The Healthiness Of The Foods In Australian Supermarkets
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
This project proposes to better understand the role of supermarkets on influencing the healthiness of the food supply. Three studies are planned which evaluate the evidence for the effect of supermarket standards on the food supply, determine whether providing nutritional data to a supermarket can change the healthiness of their food products, and identify factors that influence the development and use of supermarket standards to improve their foods.
Effects Of Testosterone And Oestrogen On Body Composition
Funder
National Health and Medical Research Council
Funding Amount
$348,768.00
Summary
Masculinising and feminising hormones such as testosterone and oestrogen respectively are important hormones controlling the amount of muscle, fat and bone in the body. By studying people with conditions such as prostate cancer where these hormone levels are disrupted, we aim to understand how testosterone and oestrogen affects various body systems, which may lead to new treatments for important public health problems of frailty, obesity and heart disease, and osteoporosis.
Targeting Depression For The Primary Prevention Of Cardiovascular Disease (CVD): The Role Of Diet In Risk Reduction
Funder
National Health and Medical Research Council
Funding Amount
$311,860.00
Summary
Traditionally, efforts to prevent people from developing cardiovascular diseases (CVD) like heart disease have focused on reducing smoking and alcohol intake and improving physical activity and diet. There is now evidence that having depression might also lead to CVD and that unhealthy eating might contribute to this relationship. This research will determine whether targeting people with depression and improving their mood through healthy eating ultimately reduces their CVD risk.
Dietary Antioxidants And Fatty Acids And Heart Disease Risk In Southern European Migrants And Indigenous Australians
Funder
National Health and Medical Research Council
Funding Amount
$304,002.00
Summary
The aim in this research program is to learn more about how nutrition, particularly different types of dietary fat and antioxidants from fruit and vegetables, can affect the risk of cardiovascular disease and diabetes. Data from Indigenous Australians known to be at high risk for these conditions, as well as Greek and Italian migrants to Australia, with low risk for cardiovascular disease, will be analyzed.
The Assessment And Treatment Of Cardiovascular Risk Factors,diabetes And Insulin Resistance In Polycystic Ovary Syndrome
Funder
National Health and Medical Research Council
Funding Amount
$304,047.00
Summary
Cardiovascular disease (CVD) and Type II Diabetes Mellitus (T2DM) are major health burdens in Australia. T2DM is increased and CVD may be increased in polycystic ovary syndrome (PCOS), a condition present in 10% of women and 30% of obese reproductive aged women. We aim to explore risk factors for CVD and T2DM in women with PCOS and to assess the effect of treatment strategies on metabolic and reproductive features in PCOS. This is crucial for reducing disease risk in this common condition.
Examining The Influence Of Neighbourhood Food And Alcohol Environments On Adolescent Health
Funder
National Health and Medical Research Council
Funding Amount
$334,414.00
Summary
The high prevalence of nutrition-related health problems in Australia underscores the growing concern about eating patterns. In order to advance our understanding of the determinants of eating behaviour it is necessary to consider the way the environment impacts on dietary intake. My planned research within this fellowship aims to generate policy relevant evidence on whether neighbourhood environments impact on food and alcohol consumption patterns as well as obesity risk as children transition ....The high prevalence of nutrition-related health problems in Australia underscores the growing concern about eating patterns. In order to advance our understanding of the determinants of eating behaviour it is necessary to consider the way the environment impacts on dietary intake. My planned research within this fellowship aims to generate policy relevant evidence on whether neighbourhood environments impact on food and alcohol consumption patterns as well as obesity risk as children transition from adolescence to adulthood.Read moreRead less