Nanoelectromechanical Mass Spectrometry with Molecular Imaging. This project aims to develop new technology to enable simultaneous measurement of the mass and conformation of single molecules. Mass spectrometry and high-resolution microscopy are independent analytical tools used widely to characterise the chemical and physical properties of molecules. This project aims to develop new technology based on advanced nanoelectromechanical systems that combines the capabilities of these complementary ....Nanoelectromechanical Mass Spectrometry with Molecular Imaging. This project aims to develop new technology to enable simultaneous measurement of the mass and conformation of single molecules. Mass spectrometry and high-resolution microscopy are independent analytical tools used widely to characterise the chemical and physical properties of molecules. This project aims to develop new technology based on advanced nanoelectromechanical systems that combines the capabilities of these complementary instruments. This would enable synchronous measurement of molecular mass and conformation with nanometre resolution. In contrast to current mass spectrometry, this technology could be operated in fluid and detect neutral species. This significant change in capability could be applied to advance biological and medical research.Read moreRead less
Advanced high resolution atomic force microscopy of biomolecules in physiological environments. The proposed research is intended to explain high resolution bioimaging problems addressed only phenomenologically before. A correct physical model would help the scientific community to optimise imaging of dynamic biological systems, extending our knowledge about the way living organisms function. With dynamic bioimaging, the mechanism of certain diseases such as Alzheimer's - where biomolecule fiber ....Advanced high resolution atomic force microscopy of biomolecules in physiological environments. The proposed research is intended to explain high resolution bioimaging problems addressed only phenomenologically before. A correct physical model would help the scientific community to optimise imaging of dynamic biological systems, extending our knowledge about the way living organisms function. With dynamic bioimaging, the mechanism of certain diseases such as Alzheimer's - where biomolecule fiber formation plays a key role - can also be addressed, thus the project has even therapeutical relevance. Furthermore, adequate description of liquid phase imaging can help engineers in the design of better hardware and software solutions, for the benefit of the bio-nanotechnological industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989615
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Melbourne Platform for Surface Characterisation of Structured Materials. The Australian economy is gradually expanding its manufacturing base through the development of the nanotechnology and biotechnology sectors. This will lead to production of a more diverse range of elaborately transformed goods. A key contributor to these export opportunities will be the nanotechnology sector since at the present time no country has a real nanotechnology based economy and there are many niche markets availa ....Melbourne Platform for Surface Characterisation of Structured Materials. The Australian economy is gradually expanding its manufacturing base through the development of the nanotechnology and biotechnology sectors. This will lead to production of a more diverse range of elaborately transformed goods. A key contributor to these export opportunities will be the nanotechnology sector since at the present time no country has a real nanotechnology based economy and there are many niche markets available for smaller countries such as Australia. This proposal helps to build quality control and characterisation infrastructure that will facilitate prototyping and design of nanoscale devices and sensors for next generation manufacturing.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0454166
Funder
Australian Research Council
Funding Amount
$1,305,029.00
Summary
Nanoscale Materials Characterization Facility. We request a transmission and a scanning electron microscope, each with specialist electron probes smaller than a nanometre, which can selectively analyse the atomic structure and chemistry of sub-nanometre regions of material.
These capabilities are essential to advance a large range of research projects at the cutting-edge of materials science and engineering, undertaken by Victoria's leading research institutions: five Victorian universities, ....Nanoscale Materials Characterization Facility. We request a transmission and a scanning electron microscope, each with specialist electron probes smaller than a nanometre, which can selectively analyse the atomic structure and chemistry of sub-nanometre regions of material.
These capabilities are essential to advance a large range of research projects at the cutting-edge of materials science and engineering, undertaken by Victoria's leading research institutions: five Victorian universities, the CSIRO, Nanotechnology Victoria Ltd, the Victorian Centre for Advanced Materials Manufacturing and the CRC for Microtechnology. Together they have contributed $2.58 million to this project.
This state-of-the-art facility will include the highest spatial resolution microscope in Australia.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882821
Funder
Australian Research Council
Funding Amount
$750,000.00
Summary
Ion Beam Nanofabrication and Characterisation Facility for Advanced Materials Research. The requested instrumentation is essential to advance a range of activities at the cutting-edge of materials research and in order to maintain word class research activities in Victoria. The instrumentation requested will build on collaborative links and cultivate enhanced usage of existing facilities between partner organisations. The facility will enhance progress in nanotechnology, biotechnology and materi ....Ion Beam Nanofabrication and Characterisation Facility for Advanced Materials Research. The requested instrumentation is essential to advance a range of activities at the cutting-edge of materials research and in order to maintain word class research activities in Victoria. The instrumentation requested will build on collaborative links and cultivate enhanced usage of existing facilities between partner organisations. The facility will enhance progress in nanotechnology, biotechnology and materials sciences, not only training the next generation of researchers to drive these critical areas, but maintaining Australia's track record as an innovator and developer of advanced materials.Read moreRead less
An investigation of growth processes, structure and properties of biogenically synthesised gold nanoparticles. Nanoparticles can have unique and interesting properties such as optical activity and redox (electronic) behaviour that can be utilised in a number of applications such as drug delivery and cancer hyperthermia treatments, coatings, electronic devices and sensors. The main aims of this research program are to produce novel nanoparticles using an innovative method which uses biological sp ....An investigation of growth processes, structure and properties of biogenically synthesised gold nanoparticles. Nanoparticles can have unique and interesting properties such as optical activity and redox (electronic) behaviour that can be utilised in a number of applications such as drug delivery and cancer hyperthermia treatments, coatings, electronic devices and sensors. The main aims of this research program are to produce novel nanoparticles using an innovative method which uses biological species such as fungi and plant extracts, and to study the growth mechanisms, structure and properties of these nanoparticles. These studies could lead to the discovery of novel nanoparticles with applications in the fields mentioned above. This project also aims to train/educate young Australian graduates in the growing area of advanced materials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775679
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Advanced Microscopy Infrastructure for use in Frontier Technologies. This proposal seeks to establish key microscopy facilities to support the research projects from leading researchers from four major Universities. The new facilities build on the close collaborative links between the partner organisations and the request is for specialised equipment that is complementary to that available at, for example, the Australian Synchrotron. The new facilities will enhance progress in the the important ....Advanced Microscopy Infrastructure for use in Frontier Technologies. This proposal seeks to establish key microscopy facilities to support the research projects from leading researchers from four major Universities. The new facilities build on the close collaborative links between the partner organisations and the request is for specialised equipment that is complementary to that available at, for example, the Australian Synchrotron. The new facilities will enhance progress in the the important areas of nanotechnology, biotechnology and advanced materials to the benefit of the community and will play a crucial role in training the next generation of researchers to drive these critical areas of science and technology.Read moreRead less
Radio-magnetic nanoparticles as bimodal positron emission tomography/magnetic resonance imaging contrast agents for dendritic cell tracking. Biomedical imaging is limited by a lack of commercial dual-mode contrast agents, which may be simultaneously used for magnetic resonance (MR) and positron emission tomography (PET) imaging. This project will develop a nanotechnology-based biocompatible dual-mode contrast agent for simultaneous PET and MR imaging, reducing associated side effects.
Advanced nanoparticle stabilisation and functionalisation: small particles with huge potential. Australia is strongly investing in nanotechnology and through the governments priority goals 'Frontier Technologies for Building and Transforming Australian Industries' it has been recognised as an important area for investment. This proposal will help develop an internationally recognised nano-industry. It is envisaged that the particles made during this work will have direct implications for the pub ....Advanced nanoparticle stabilisation and functionalisation: small particles with huge potential. Australia is strongly investing in nanotechnology and through the governments priority goals 'Frontier Technologies for Building and Transforming Australian Industries' it has been recognised as an important area for investment. This proposal will help develop an internationally recognised nano-industry. It is envisaged that the particles made during this work will have direct implications for the public - creating a new class of medical diagnostic particles with better resolution and specificity. These particles have the potential to diagnose patients more precisely and at an earlier stage than is currently available. Additionally, these particles could be designed to load drugs and hence could be used to treat diseases such as cancer.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989915
Funder
Australian Research Council
Funding Amount
$127,000.00
Summary
X-ray Nano-scale Coherence Facility. Australia is rapidly developing into a world leader for x-ray imaging. This position has been supported by leading research groups and more recently by the development of the Australian Synchrotron. This project will fill a vital missing link in the experimental capability of Australian researchers - a flexible facility that can provide a nanoscale x-ray source. This enhanced capability will lead to new developments in coherent imaging methods. These new meth ....X-ray Nano-scale Coherence Facility. Australia is rapidly developing into a world leader for x-ray imaging. This position has been supported by leading research groups and more recently by the development of the Australian Synchrotron. This project will fill a vital missing link in the experimental capability of Australian researchers - a flexible facility that can provide a nanoscale x-ray source. This enhanced capability will lead to new developments in coherent imaging methods. These new methods will be used in the study of biological systems, leading to better drug design as well as in the study of materials, leading to stronger and lighter components. Read moreRead less