A high throughput Grid based environment for real time bio-medical imaging. Together with Leica, we will build a virtual microscope facility that will provide substantial functionality not currently available in Australia. This facility will have major national and international impact on bio-medical imaging. The software solutions and infrastructure, developed as part of this program will have considerable commercial and strategic value in their own right. One guaranteed avenue for exploitation ....A high throughput Grid based environment for real time bio-medical imaging. Together with Leica, we will build a virtual microscope facility that will provide substantial functionality not currently available in Australia. This facility will have major national and international impact on bio-medical imaging. The software solutions and infrastructure, developed as part of this program will have considerable commercial and strategic value in their own right. One guaranteed avenue for exploitation of the software will clearly be through our industry partner, Leica. Importantly, our proposal consolidates a critical mass of expertise connecting biomedical with computer science, thereby addressing a well-recognised constraint that to date has limited their national and international impact.Read moreRead less
Micropapillary Adenocarcinoma: The Emergence Of A Discrete Lung Cancer Phenotype And Its Genomic And Transcriptomic Characterization.
Funder
National Health and Medical Research Council
Funding Amount
$117,565.00
Summary
I believe I can describe a new subtype of lung cancer, which has never been classified by the World Health Organization. This has been previously mis-classified or simply ignored. My hypothesis is that this is a distinct disease by virtue of patterns of genetic abnormalities as well as features visible under the microscope. I also believe it is one of the most aggressive cancers and needs new treatments.
Rapid, Point Of Care Diagnostic Tests To Differentiate HA Subtypes In Patients Samples
Funder
National Health and Medical Research Council
Funding Amount
$168,293.00
Summary
A number of rapid, point-of-care tests are available for the detection of human and avian influenza types, but they vary greatly in sensitivity. In particular, these tests are based on current strains of H5 (avian) influenza, and may be unable to detect variant or pandemic strains, and negative results can give the false impression that patients do not have H5 influenza. We will develop rapid, point-of-care tests based on highly conserved parts of the virus, so that all H5 strains (current and f ....A number of rapid, point-of-care tests are available for the detection of human and avian influenza types, but they vary greatly in sensitivity. In particular, these tests are based on current strains of H5 (avian) influenza, and may be unable to detect variant or pandemic strains, and negative results can give the false impression that patients do not have H5 influenza. We will develop rapid, point-of-care tests based on highly conserved parts of the virus, so that all H5 strains (current and future) can be detected with equal sensitivity, along with the H1 and H3 strains that are currently found in man to provide a definitive diagnosis. These tests will be valuable in the identification and differentiation of pandemic influenza cases, allowing better use of public health resources, especially against a background of continuing standard (H1 and H3) influenza infections.Read moreRead less
Domain-specific visual languages for big data analytics applications. This project aims to invent domain-specific visual languages and support model-driven engineering based infrastructure so domain experts can specify, generate and apply complex data analytics and visualisation techniques. Many domains, including intelligent transport, business intelligence, and population health, need more effective “big data” analytics and visualisation. A challenge is to combine detailed domain knowledge – w ....Domain-specific visual languages for big data analytics applications. This project aims to invent domain-specific visual languages and support model-driven engineering based infrastructure so domain experts can specify, generate and apply complex data analytics and visualisation techniques. Many domains, including intelligent transport, business intelligence, and population health, need more effective “big data” analytics and visualisation. A challenge is to combine detailed domain knowledge – what the data means and what it can be used for – with sophisticated, scalable computational techniques to mine and present information from the huge volumes of raw data. This project is expected to improve productivity and quality of big data analytics and visualisation in critical domains.Read moreRead less
Metamorphic slices and their applications in fault localization. The main purpose of this project is to enhance the quality of software. The expected outcomes include the delivery of new cost-effective methods to debug software, and the extension of current debugging methods to be applicable in wider contexts.
Cost-effective use of assertions in the verification and validation of distributed and real-time systems. The project will reinforce Australia as a world leader in empirical software engineering and software verification and validation research, thus building on Australia's strengths in ICT research and innovation. Through the involvement of a local software verification and validation company and through industrial case studies, this project will also improve the software verification and valid ....Cost-effective use of assertions in the verification and validation of distributed and real-time systems. The project will reinforce Australia as a world leader in empirical software engineering and software verification and validation research, thus building on Australia's strengths in ICT research and innovation. Through the involvement of a local software verification and validation company and through industrial case studies, this project will also improve the software verification and validation capabilities of local industry, allow them to save software development costs, and improve the quality of the software produced.Read moreRead less
Integration of Metamorphic Testing and Model Checking. This project proposes an innovative approach of integrating metamorphic testing and model checking. Its main outcome will be to deliver a comprehensive testing method that will help to reduce errors and costs in software development and consequently to improve the quality of software systems. Since software is pervasive and ubiquitous, our results will improve the nation's software productivity and quality. Thus, our results will help in ra ....Integration of Metamorphic Testing and Model Checking. This project proposes an innovative approach of integrating metamorphic testing and model checking. Its main outcome will be to deliver a comprehensive testing method that will help to reduce errors and costs in software development and consequently to improve the quality of software systems. Since software is pervasive and ubiquitous, our results will improve the nation's software productivity and quality. Thus, our results will help in raising our nation's competitive advantage towards the goal of becoming a leading nation in the software industry among Asia-Pacific countries. Furthermore, this collaboration will help young Australian researchers to link to the Chinese Academy of Sciences, a leading-edge international research institute.Read moreRead less
Metamorphic Testing: An In-Depth Study to Enhance the Failure-Detection Capability of Software Testing Without an Oracle. Nowadays, software is pervasive and ubiquitous. It plays a significant role in the daily lives of all kinds of people. The Australian software industry has bloomed in recent years. Our research results will improve the cost-effectiveness of software development, thereby upgrading the nation's software productivity and quality. These factors are conducive to the export of soft ....Metamorphic Testing: An In-Depth Study to Enhance the Failure-Detection Capability of Software Testing Without an Oracle. Nowadays, software is pervasive and ubiquitous. It plays a significant role in the daily lives of all kinds of people. The Australian software industry has bloomed in recent years. Our research results will improve the cost-effectiveness of software development, thereby upgrading the nation's software productivity and quality. These factors are conducive to the export of software produced by Australians and helpful in raising our nation's competitive advantage towards the goal of becoming a leading nation in the software industry among Asia-Pacific countries.Read moreRead less
A Comprehensive Testing Methodology for Embedded Software. Embedded systems are a bedrock technology for many high-technology industries. They are used in many safety-critical situations, such as medical devices and car control systems, amongst hundreds of other applications. Unfortunately, current practice still sometimes results in disastrous mistakes remaining undetected, leading to multi-million dollar losses and in some cases even deaths. Improved testing methods for these systems offer ....A Comprehensive Testing Methodology for Embedded Software. Embedded systems are a bedrock technology for many high-technology industries. They are used in many safety-critical situations, such as medical devices and car control systems, amongst hundreds of other applications. Unfortunately, current practice still sometimes results in disastrous mistakes remaining undetected, leading to multi-million dollar losses and in some cases even deaths. Improved testing methods for these systems offer the potential of reducing such catastrophic losses. Improved embedded system testing techniques can offer Australia a competitive advantage in this strategically important industry. We will work to distribute our results to the Australian embedded systems community.Read moreRead less