Effects Of Pharmacological Modification Of Ion Channel Activity On The Excitability Of Normal And Diabetic Nerves.
Funder
National Health and Medical Research Council
Funding Amount
$389,232.00
Summary
Neuropathic disturbances due to diabetes can destroy the quality of life and place a major cost burden on society. This project will provide insight into the actions of specific pharmaceutical agents on human nerves in both healthy subjects and diabetic patients with a view to establishing how these drugs reduce neuropathic symptoms in real life. The study will provide information regarding the underlying causes of neuropathic symptoms in diabetes and may help guide future treatments.
Diabetic neuropathy causes severe disability, with pain, loss of sensation and weakness. The current project will assess the utility of a new testing method, known as nerve excitability assessment, as a method of detecting early changes in nerve function in diabetic patients. If this technique proves useful in detecting early nerve damage, it will assist in the development of therapeutic and preventative treatments for neuropathy in diabetic patients.
The Effectiveness Of A New Diabetic Retinopathy Screening Strategy For People With Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
A simple way to prevent and treat people suffering from diabetic retinopathy, a terrible eye disease resulting from diabetes, is to identify the disease early. This research will screen people with diabetes who do not think they have diabetic retinopathy or who have not had an eye examination in the last 2 years when attending a pathology centre for their diabetes-related tests. The study will follow participants over 4 years to look at subsequent treatment and compliance with eye examination.
Behavioural And Health Services Research In Ophthalmology: Gaining And Implementing Evidence To Improve Patient Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$253,465.00
Summary
This research program is focused on improving the outcomes for people with eye disease. Through a number of projects in different health care settings including ophthalmic services, low vision rehabilitation services and residential care, this research program will implement and evaluate new treatments or models of care that can improve people’s well-being, quality of life and clinical outcomes in a cost-effective manner.