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Field of Research : Evolutionary Biology
Research Topic : developmental problems
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Evolutionary Biology (17)
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  • Researchers (28)
  • Funded Activities (17)
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  • Active Funded Activity

    Discovery Projects - Grant ID: DP210101423

    Funder
    Australian Research Council
    Funding Amount
    $518,000.00
    Summary
    The evolution of the alternation of generations in land plants. This project aims to investigate how a genetic system, comprised of a homeodomain protein encoding gene family controlling the haploid to diploid transition, has evolved during land plant evolution. The project expects to generate new knowledge concerning the evolution of land plants from which our food and fibre are derived. The intended outcomes include an elucidation of how an ancestral genetic network was elaborated during the e .... The evolution of the alternation of generations in land plants. This project aims to investigate how a genetic system, comprised of a homeodomain protein encoding gene family controlling the haploid to diploid transition, has evolved during land plant evolution. The project expects to generate new knowledge concerning the evolution of land plants from which our food and fibre are derived. The intended outcomes include an elucidation of how an ancestral genetic network was elaborated during the evolution of a multicelluar organism, including the retention of ancestral functions and the origins of new functions. An anticipated benefit is the ability to manipulate the the growth and development of plants based on fundamental principles, which has broad agricultural implications.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP200100225

    Funder
    Australian Research Council
    Funding Amount
    $540,000.00
    Summary
    The origin and evolution of the land plant meristem. This project aims to identify the extent of overlap between the genetic determinants of the gametophyte and sporophyte shoot meristems. The project expects to generate new knowledge of the evolution and development of land plants by applying comparative genomics and new technologies to a novel model genetic system. Expected outcomes include an elucidation of the genetic basis for one of the key morphological adaptations for life on land. Th .... The origin and evolution of the land plant meristem. This project aims to identify the extent of overlap between the genetic determinants of the gametophyte and sporophyte shoot meristems. The project expects to generate new knowledge of the evolution and development of land plants by applying comparative genomics and new technologies to a novel model genetic system. Expected outcomes include an elucidation of the genetic basis for one of the key morphological adaptations for life on land. The ability to manipulate the growth and development of plants via the activity of meristems based on fundamental principles has broad agricultural implications.
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    Funded Activity

    Discovery Early Career Researcher Award - Grant ID: DE180100306

    Funder
    Australian Research Council
    Funding Amount
    $365,058.00
    Summary
    Does spurious maternal-fetal signalling support the evolution of a placenta. This project aims to test a model that explains how the placenta has evolved as a new organ more than 100 times in fishes, reptiles, and mammals including our own ancestors. The project will assess whether regulatory components of the placenta evolve as a result of spurious maternal-fetal signalling following egg retention and eggshell loss in viviparous reptiles. Expected outcomes of this project include a new understa .... Does spurious maternal-fetal signalling support the evolution of a placenta. This project aims to test a model that explains how the placenta has evolved as a new organ more than 100 times in fishes, reptiles, and mammals including our own ancestors. The project will assess whether regulatory components of the placenta evolve as a result of spurious maternal-fetal signalling following egg retention and eggshell loss in viviparous reptiles. Expected outcomes of this project include a new understanding of how complex organs originate and evolve in animals. This will benefit society through a broader depth of understanding of our own evolutionary history and provides a framework for future studies to investigate the origin and evolution of organs more broadly in animals.
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    Funded Activity

    Discovery Projects - Grant ID: DP170100049

    Funder
    Australian Research Council
    Funding Amount
    $415,500.00
    Summary
    Evolution of the alternation of generations in the land plant life cycle. This project aims to investigate the genetic and evolutionary basis of land plants’ dimorphic life cycle where a single genome can generate two body plans. Like animals, land plants spend part of their life as a diploid, where meiosis generates haploid spores. Unlike animals, these spores grow into multicellular organisms before generating gametes. The project will study a homeodomain protein encoding a gene family that co .... Evolution of the alternation of generations in the land plant life cycle. This project aims to investigate the genetic and evolutionary basis of land plants’ dimorphic life cycle where a single genome can generate two body plans. Like animals, land plants spend part of their life as a diploid, where meiosis generates haploid spores. Unlike animals, these spores grow into multicellular organisms before generating gametes. The project will study a homeodomain protein encoding a gene family that controls the haploid to diploid transition in unicellular algae and fungi. It will investigate land plant genes in a flowering plant and a liverwort. These findings could help scientists understand and manipulate important processes such as pollen and seed production.
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    Funded Activity

    ARC Future Fellowships - Grant ID: FT100100763

    Funder
    Australian Research Council
    Funding Amount
    $697,522.00
    Summary
    Evolution of vascular tissue in land plants. This project will investigate genetic mechanisms of secondary cell wall thickening in a new genetic model representing an ancient plant lineage. This research will reveal the evolutionary origin of plant vascular tissue; a significant innovation that allowed increased size of plants and the origin of wood.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP200100344

    Funder
    Australian Research Council
    Funding Amount
    $760,000.00
    Summary
    Inflammation as an early form of maternal-fetal signalling in pregnancy. The project aims to understand the role of inflammatory signalling in marsupial pregnancy. This project is expected to explain why inflammation, a processes normally confined to injury and infection, is a part of reproduction in live-bearing mammals. Outcomes of this project include robust measures of the capacity for, impact of, and evolution of, inflammatory signalling in marsupial pregnancy. The project will provide new .... Inflammation as an early form of maternal-fetal signalling in pregnancy. The project aims to understand the role of inflammatory signalling in marsupial pregnancy. This project is expected to explain why inflammation, a processes normally confined to injury and infection, is a part of reproduction in live-bearing mammals. Outcomes of this project include robust measures of the capacity for, impact of, and evolution of, inflammatory signalling in marsupial pregnancy. The project will provide new knowledge about the unique biology of Australia's marsupial fauna.This project will provide significant benefits, including enhanced capacity for reproduction research in Australia, new international collaborations between Melbourne and Yale, and a new explanation for the puzzling role of inflammation in pregnancy.
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    Funded Activity

    Discovery Projects - Grant ID: DP160104427

    Funder
    Australian Research Council
    Funding Amount
    $399,100.00
    Summary
    Evolution of the dermomyotome in vertebrates. The project seeks to understand how different muscle populations within the embryo form and have evolved within the vertebrate phylogeny. All amniote muscles, except that of the head, derive from a transient embryonic structure termed the dermomyotome. The formation of muscle from the dermomyotome of amniotes uses a highly conserved mechanism that is distinct from that deployed by bony fish and amphibians. How the dermomyotome evolved to generate th .... Evolution of the dermomyotome in vertebrates. The project seeks to understand how different muscle populations within the embryo form and have evolved within the vertebrate phylogeny. All amniote muscles, except that of the head, derive from a transient embryonic structure termed the dermomyotome. The formation of muscle from the dermomyotome of amniotes uses a highly conserved mechanism that is distinct from that deployed by bony fish and amphibians. How the dermomyotome evolved to generate the distinct types of locomotor systems we see deployed throughout the vertebrate phylogeny remains unresolved. This project aims to contribute to an understanding of how different locomotor strategies deployed at important evolutionary transitions were generated.
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    Funded Activity

    Discovery Projects - Grant ID: DP190102204

    Funder
    Australian Research Council
    Funding Amount
    $380,000.00
    Summary
    How limbs evolved from fins: the role of somite cells. This project aims to investigate the developmental basis of vertebrate appendage diversity and how during evolution limbs became fins. The project expects to determine how specific populations of cells that regulate fin formation arise during development, the genetic basis of their function, and how their role in development has evolved in lineages with divergent appendage anatomy. Expected outcomes include understanding the molecular basis .... How limbs evolved from fins: the role of somite cells. This project aims to investigate the developmental basis of vertebrate appendage diversity and how during evolution limbs became fins. The project expects to determine how specific populations of cells that regulate fin formation arise during development, the genetic basis of their function, and how their role in development has evolved in lineages with divergent appendage anatomy. Expected outcomes include understanding the molecular basis of the fin-limb transition and the origin of divergent appendage patterning systems. This should provide significant benefits by advancing our knowledge of the relationship between evolution and development, and understanding limb defects, which are amongst the most common of human congenital malformations.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP200103219

    Funder
    Australian Research Council
    Funding Amount
    $418,000.00
    Summary
    Fins to Limbs: Investigating the Evolution of complex Limb Musculature. This application aims to investigates the basis of the fin-to-limb transition, an event that set the stage for the entire tetrapod radiation. This project expects to generate new knowledge concerning the natural history of vertebrates using a multidisciplinary approach that combines paleontology and embryology of unique Australian fauna. While the skeletal changes associated with the move from water to land have been investi .... Fins to Limbs: Investigating the Evolution of complex Limb Musculature. This application aims to investigates the basis of the fin-to-limb transition, an event that set the stage for the entire tetrapod radiation. This project expects to generate new knowledge concerning the natural history of vertebrates using a multidisciplinary approach that combines paleontology and embryology of unique Australian fauna. While the skeletal changes associated with the move from water to land have been investigated, little is known about the origin of tetrapod limb muscles. This proposal has as an expected outcome, a determination of how limb muscles arose during evolution. This knowledge should provide significant benefits by transforming our understanding of the origins of the tetrapod body plan and our own natural history.
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    Funded Activity

    ARC Future Fellowships - Grant ID: FT170100259

    Funder
    Australian Research Council
    Funding Amount
    $736,828.00
    Summary
    How does developmental plasticity shape adaptation to environmental change? This project aims to address how animals adapt to environmental change by examining a process largely ignored in current studies: how the environment alters animal development. This project expects to generate new knowledge in the area of the genetics of adaptation using an innovative approach to determine how genetic variation, environmental conditions, and development interact to shape adaptation to changing environmen .... How does developmental plasticity shape adaptation to environmental change? This project aims to address how animals adapt to environmental change by examining a process largely ignored in current studies: how the environment alters animal development. This project expects to generate new knowledge in the area of the genetics of adaptation using an innovative approach to determine how genetic variation, environmental conditions, and development interact to shape adaptation to changing environments. Expected outcomes of this project include enhancing predictions of how species respond to climate change and building capacity for international collaborations. The intended impact of this project is to increase our understanding of how animals respond to environmental change by determining how multiple environmental cues act together to alter development, and how the genetic makeup of the individual affects these responses.
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