Multidisciplinary Translational Research To Address Social Disparities In Osteoporosis: Understanding The Social Context Of Biological Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$419,180.00
Summary
Osteoporosis (OP) prevalence is greater for disadvantaged groups, as are less healthy lifestyles. Whilst reasons for this social gradient of OP are unknown, some biological phenomena are influenced by lifestyle factors. I will provide novel evidence about biological mechanisms underlying the social gradient of OP (epigenetics), and, using that information, engage disadvantaged communities in multidisciplinary discussions to inform effective public health interventions (community engagement).
Interfacing Epidemiology With Systems Biology For Disease Prevention
Funder
National Health and Medical Research Council
Funding Amount
$687,975.00
Summary
Over recent time, allergic and some autoimmune diseases have increased among modern children. The change has been too rapid to be due to genetic factors alone and my research program examines also the role of the changing environment. It also examines the health effects of new man-made exposures like plastic product chemicals.
The Contribution Of Home Language Exposure To Intergenerational Transmission Of Inequality
Funder
National Health and Medical Research Council
Funding Amount
$1,281,706.00
Summary
The amount of language stimulation from parent to child could be the key driver behind intergenerational inequality. Children learn language through social interaction and this study will significantly enhance our current understanding of exposure to language in the child's home environment. The study will demonstrate how inequalities in the early years have far reaching consequences for later health and development.
Determinants Of Child Health And Development: Populations, Partnerships, Pathways And Prevention
Funder
National Health and Medical Research Council
Funding Amount
$8,214,333.00
Summary
There are considerable challenges to the study of complex health and developmental problems in children and young people. Despite increasing prosperity in Australia, many of these problems are not abating and some appear to be increasing. These include low birthweight, behavioural and mental health problems, autism, obesity and, in Indigenous children, infections. This Program proposes investigating these problems with a view to prevention, thus meeting the national research priority of Promotin ....There are considerable challenges to the study of complex health and developmental problems in children and young people. Despite increasing prosperity in Australia, many of these problems are not abating and some appear to be increasing. These include low birthweight, behavioural and mental health problems, autism, obesity and, in Indigenous children, infections. This Program proposes investigating these problems with a view to prevention, thus meeting the national research priority of Promoting and Maintaining Good Health, particularly _a healthy start to life� and _preventive health care�. The Program is unique in that it brings together a multi-disciplinary team of researchers of international repute to investigate these complex issues. The research team comprises epidemiologists, clinicians, developmental psychologists, biostatisticians, sociologists and other social scientists. This team has a proven track record in producing research outcomes that have translated into innovative health policy and practice in areas as diverse as: - the use of folic acid in spina bifida prevention - understanding cerebral palsies - suicide prevention and mental health in children and young people - Aboriginal child health and development - intellectual disabilities including Rett syndrome and autism - in vitro fertilisation and birth defects. The factors influencing how children develop into young adults include genetic inheritance, nutrition and growth, and family, socioeconomic and environmental conditions. This work demands new ways of measuring and analysing these factors in populations of children and their families. Western Australia is one of only three sites in the world to have comprehensive linked health data on the whole of its population of children and their families. This Program comprises five overlapping themes of research planned around these unique population databases. The five themes are: - social, economic and psychological influences on child health and development - many paths to poor health are linked to social disadvantage. Examining these issues may explain why some childhood conditions are worsening or not improving - pathways to wellbeing, resilience and developmental disorders, including intellectual disability, autism, birth defects and cerebral palsy - nutrition and growth, particularly as it relates to low birthweight, childhood obesity and mental health - infectious disease, its causes and its influence on lifelong health problems and disabilities - Aboriginal health _ whilst spanning each of the research themes above, it presents its own unique challenges and requires it�s own unique solutions. This Program will investigate how children develop into young adults and will examine the influence of their families, nutrition and growth and socioeconomic and environmental conditions. It will develop new ways of measuring and analysRead moreRead less
Associations Between Urban Nature And Cardiovascular Disease Risk
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Cardiovascular disease (CVD) is the leading cause of death in Australia. Urban nature (e.g. greenness, water, species diversity) is likely to protect against CVD, yet researchers lack knowledge about how this occurs. This project will develop new methods to measure urban nature and examine the relationships with different CVD risk factors (e.g. physical activity, air quality). The results of this project will inform urban planning policy, and help to create healthy cities that reduce CVD.
Oral Health Research For The Australian Population
Funder
National Health and Medical Research Council
Funding Amount
$2,501,265.00
Summary
This program will build capacity and expertise in Australia s population health research workforce. The program will pursue the broad research theme adding value to oral health surveys . Over a period of five years, eight junior researchers will work on projects that enhance the value of six oral health surveys within the Australian Research Centre for Population Oral Health at The University of Adelaide. Projects will range from analysis of inflammation caused by periodontal (gum) disease in th ....This program will build capacity and expertise in Australia s population health research workforce. The program will pursue the broad research theme adding value to oral health surveys . Over a period of five years, eight junior researchers will work on projects that enhance the value of six oral health surveys within the Australian Research Centre for Population Oral Health at The University of Adelaide. Projects will range from analysis of inflammation caused by periodontal (gum) disease in the Australian population, to evaluation of school dental services provided over the last 30 years. Team investigators will work on these surveys to tackle public health problems confronting four distinct dental generations of Australians: _1) people in the oldest tooth loss generation who have lost, on average, half of their natural teeth; 2) the amalgam generation of middle-aged adults who had unprecedented numbers of cavities that are now filled - treatment that requires extensive maintenance and repair; 3) the younger fluoride generation that has historically-low rates of dental decay; 4) and today s pre-schoolers among whom there is disturbing evidence that oral disease is becoming concentrated within the most disadvantaged segments of the population. Their work will improve the information base needed to promote oral health and prevent oral illness in the Australian population.Read moreRead less
Turning Points: Breaking Intergenerational Cycles Of Intimate Partner Abuse And Social Adversity
Funder
National Health and Medical Research Council
Funding Amount
$1,328,354.00
Summary
Intimate partner abuse (IPA) is estimated to affect one in four women at some stage in their lives, and to impact on the lives of at least one million Australian children annually. This study will investigate the extent to which exposure to intimate partner abuse during pregnancy and in the first 12 months postpartum predicts child outcomes in middle childhood. The study will provide foundations for better targeting and tailoring of early intervention strategies to support children at risk of ad ....Intimate partner abuse (IPA) is estimated to affect one in four women at some stage in their lives, and to impact on the lives of at least one million Australian children annually. This study will investigate the extent to which exposure to intimate partner abuse during pregnancy and in the first 12 months postpartum predicts child outcomes in middle childhood. The study will provide foundations for better targeting and tailoring of early intervention strategies to support children at risk of adverse outcomes.Read moreRead less