The effect of genomic variants on Indigenous health. The effect of genomic variants on Indigenous health. This project aims to examine the genetic variants introduced by Europeans (and other groups) into the genomes of the Aboriginal Australian population. The rate of metabolic diseases such as diabetes and hypertension is very high in Australia’s Indigenous populations. While an energy-rich Western diet has been suggested as the major cause, the contribution of genomic variants (mutations) rema ....The effect of genomic variants on Indigenous health. The effect of genomic variants on Indigenous health. This project aims to examine the genetic variants introduced by Europeans (and other groups) into the genomes of the Aboriginal Australian population. The rate of metabolic diseases such as diabetes and hypertension is very high in Australia’s Indigenous populations. While an energy-rich Western diet has been suggested as the major cause, the contribution of genomic variants (mutations) remains unclear. Anticipated outcomes are better understandings of both the benign and deleterious variants introduced into Aboriginal Australian populations and how these contribute to disease susceptibility.Read moreRead less
Trails of migration out of Africa in harmful mutations of the First Peoples. This project aims to study harmful mutations specific to Indigenous populations. The process of migration out of Africa has left its footprints in the mutations present in world populations. By investigating these unique signatures, this project aims to characterise the harmful mutations specific to Aboriginal Australians using the whole genome sequences of the First Peoples. The expected outcomes will benefit future ....Trails of migration out of Africa in harmful mutations of the First Peoples. This project aims to study harmful mutations specific to Indigenous populations. The process of migration out of Africa has left its footprints in the mutations present in world populations. By investigating these unique signatures, this project aims to characterise the harmful mutations specific to Aboriginal Australians using the whole genome sequences of the First Peoples. The expected outcomes will benefit future Aboriginal health research to better understand the mutations associated with various genetic diseases.Read moreRead less