Understanding Burn Injuries In Aboriginal And Torres Strait Islander Children: Treatment, Access To Services And Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$911,798.00
Summary
This is the first large scale study to systematically examine the burden of burn injury in Aboriginal and Torres Strait Islander children, including care and cost of treatment, and relationship between access to treatment and functional outcomes. With a team comprising epidemiologists, burns clinicans and Aboriginal health researchers, this study will generate important new research evidence to improve care in this over-represented and vulnerable population.
THE NATURAL HISTORY OF COGNITIVE IMPAIRMENT AND DEMENTIA IN A STROKE COHORT
Funder
National Health and Medical Research Council
Funding Amount
$290,747.00
Summary
In a current NHMRC-funded study, we have examined 200 stroke patients (and 100 control subjects) at 3 months after a stroke and one year later, and identified those who have impairment in memory and other cognitive functions. We have also studied these subjects in detail from a psychiatric perspective and performed brain scans on them using magentic resonance imaging. We find that many stroke patients have problems with their cognitive functioning which has a major impact on their lives. A large ....In a current NHMRC-funded study, we have examined 200 stroke patients (and 100 control subjects) at 3 months after a stroke and one year later, and identified those who have impairment in memory and other cognitive functions. We have also studied these subjects in detail from a psychiatric perspective and performed brain scans on them using magentic resonance imaging. We find that many stroke patients have problems with their cognitive functioning which has a major impact on their lives. A large number also become depressed. These consequences of stroke are not given sufficient importance by clinicians. The fact that stroke is a common problem in the elderly, and our society is aging, makes this a problem of major public health significance. In the new proposal, we plan to study these subjects up to 3 years with repeat neuropsychiatric assessments and brain scans to investigate the natural history of stroke-related cognitive impairment. We will determine whether further new cases of dementia develop in the period 1-3 years, what happens to the brain lesions picked up on brain scans, and how these deficiencies affect the patients' living status and their longevity. We will be able to determine the factors that lead to a good outcome, and suggest strategies that may be applicable to improve the functioning of these individuals.Read moreRead less
Quantification of the Remineralisation of Enamel. This project has three specific aims:
1. To quantify the ultrastructure and mechanisms of remineralisation of enamel using scanning and transmission electron microscopy.
2. To determine the mechanical properties of remineralised tissue and compare with those of sound enamel.
3. To develop an in-vivo optical fibre probe for monitoring and quantifying the changes of mineralised carious tissue during remineralisation.
This project will enable ....Quantification of the Remineralisation of Enamel. This project has three specific aims:
1. To quantify the ultrastructure and mechanisms of remineralisation of enamel using scanning and transmission electron microscopy.
2. To determine the mechanical properties of remineralised tissue and compare with those of sound enamel.
3. To develop an in-vivo optical fibre probe for monitoring and quantifying the changes of mineralised carious tissue during remineralisation.
This project will enable patients prone to orthodontic induced root resorption to be identified and also to assist with validating repair of enamel tooth structure in a non-surgical manner. It is anticipated to result in the development of a novel fibre optic instrument with applications beyond dentistry.
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