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The Future In Our Hands: Screening For Preclinical Alzheimer's Disease By Analysing Hand Movements
Funder
National Health and Medical Research Council
Funding Amount
$899,782.00
Summary
Alzheimer's disease (AD) starts damaging the brain 10-20 years before memory problems begin. By the time of diagnosis, it is hard to treat because the damage is so severe. We need a way to detect AD much earlier. We will develop a simple new computer test to detect early signs of AD by recording and analysing hand movements. Then people can start prevention earlier and scientists can research better treatments to improve people's quality of life and reduce the number of people with dementia.
ASCAPE: Audio App-delivered Screening For Cognition And Age-related Health In Older Prisoners
Funder
National Health and Medical Research Council
Funding Amount
$844,050.00
Summary
This study aims to develop and test a new, innovative health screening app to examine the health and functioning of older, ageing prisoners in Australia. The app will deliver a range of health and functioning measures via audio, minimising the need for literacy skills and for staff supervision during testing. It is hoped that this app will be easily implemented in prisons in future, to enable better health management for this growing cohort with complex health needs.
Targeting Pathogenic TAR DNA-binding Protein 43 To Treat Frontotemporal Dementia And Motor Neuron Disease
Funder
National Health and Medical Research Council
Funding Amount
$687,444.00
Summary
Frontotemporal dementia and motor neuron Disease are rapidly progressive and fatal neurodegenerative diseases that affect people in their prime. Poor understanding of the processes that lead to these diseases have slowed drug development. Through innovative experimental design, we aim to decipher a novel disease mechanism that involves specific molecular interactions and translate these findings into new therapies for the diseases.
Using A National Level Multi-registry Analysis To Determine Whether Prescribed Anti-platelet Therapies Post-stroke Can Modify The Risk Of Cognitive Decline Or Dementia
Funder
National Health and Medical Research Council
Funding Amount
$446,302.00
Summary
Stroke survivors are at risk of dementia. Blood brain barrier damage after stroke may allow drugs in the bloodstream, which can be toxic to brain cells, to enter the brain. Clopidogrel, a drug commonly used after stroke, blocks a receptor essential for brain repair. After stroke, clopidogrel may access the brain and compromise repair processes, increasing the risk of dementia. We will link use of clopidogrel to the risk of dementia after stroke, using national Swedish health registry data.
Communication Connect: Improving Long Term Communication And Mental Health Outcomes Following Stroke And Brain Injury
Funder
National Health and Medical Research Council
Funding Amount
$1,809,756.00
Summary
The 250,000 Australians living in the community with communication disability caused by stroke and traumatic brain injury experience unacceptably high rates of depression, anxiety, inactivity and social isolation. Their carers experience high levels of burden, and they struggle to access health and community services. We aim to develop and test a program of community and self-managed care, aimed at reversing these negative impacts and reducing reliance on high cost health care services.
Leaving No-one Behind: Informing Indigenous Aged Care Policy With Big Data.
Funder
National Health and Medical Research Council
Funding Amount
$1,668,851.00
Summary
Very little is known about older Indigenous people in aged care. Led by Indigenous people, this project will use a unique national dataset to answer questions on the experiences of Indigenous people in aged care, focusing on access and barriers to services and care, quality and safety of care and whether the care they receive meets their health needs. This research will inform service improvements and ensure older Indigenous people are not forgotten in much-needed aged care reforms.
Advancing Equitable And Non-discriminatory Access To Health Services For First Nations Peoples: A Multidisciplinary Queensland Human Rights Act Case Study
Funder
National Health and Medical Research Council
Funding Amount
$1,279,602.00
Summary
The objective of this innovative study is to apply a multidisciplinary, right to health lens to critically explore & bring to light Indigenous Australians' experiences of racial discrimination in accessing equitable, quality & timely health services in urban, rural & remote locations. Research outcomes will be synthesised into a suite of project deliverables, with Multi-Stakeholder Advisory Group guidance & community co-design, to advance inter-generational health justice.