Improving Patient Access To Novel Cancer Drugs In Australia: Striking The Balance
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Cancer patients in Australia may experience delays before they can benefit from new expensive drugs because of the lengthy existing processes to evaluate new medicines by the Department of Health. I will study how to improve the existing drug evaluation processes to make timely but informed funding decisions. This work will improve patient outcomes from early access to effective new cancer drugs and help the government make a wiser spending of public funds.
Increasing Population Health By Making Better Funding Decisions: Estimation Of The Cost-effectiveness Threshold For The Australian Health System
Funder
National Health and Medical Research Council
Funding Amount
$341,368.00
Summary
This project will estimate the Australian opportunity cost of decisions to fund new health care technologies, such as pharmaceuticals and medical devices. The opportunity cost represents the health benefits that could be achieved if the resources used to fund a new technology are used to fund the best alternative technology or service instead. We will then disseminate the information to decision makers, to improve funding decisions, and hence the efficiency of the Australian health care system.
Centre For Research Excellence In Reducing Healthcare Associated Infection
Funder
National Health and Medical Research Council
Funding Amount
$2,495,795.00
Summary
Each year in Australia 180,000 patients suffer a healthcare associated infection. Risk can be reduced with relatively simple technology but substantial costs arise with system wide adoption and monitoring. The economic paradigm is that funds can be invested for infection reduction to save costs and lives. The CRE will reveal the cost-effectiveness of infection control programmes and show health services decision-makers how to improve patient outcomes, save resources and save lives.
Developing A Common Outcome Measure For Priority Setting In Health: Validation Of The 'Transfer To Utility' Technique
Funder
National Health and Medical Research Council
Funding Amount
$314,100.00
Summary
The economic evaluation of health programs is a common requirement of funders and purchasers seeking to get the best value from the health dollar. But researchers employ a wide range of disease specific and generic health status instruments to describe trial outcomes, making comparison between diverse interventions difficult. In response to this problem a 'Transfer to Utility' or TTU technique was developed by Dr Segal and colleagues, to translate diverse outcomes reported in clinical trials, in ....The economic evaluation of health programs is a common requirement of funders and purchasers seeking to get the best value from the health dollar. But researchers employ a wide range of disease specific and generic health status instruments to describe trial outcomes, making comparison between diverse interventions difficult. In response to this problem a 'Transfer to Utility' or TTU technique was developed by Dr Segal and colleagues, to translate diverse outcomes reported in clinical trials, into a utility score, so the performance of diverse health interventions can be expressed in cost-QALY and compared. The technique establishes a statistical transformation between instruments commonly used in clinical trials and a utility value. While the technique appears highly useful, based on a priority setting exercise in osteoarthritis enabling 20 disparate interventions to be compared its validity and applicability in other contexts is not established. The purpose of the grant is to explore the TTU technique to i) establish the best method for estimating the regression equation between common health outcome measures and a utility score and validating that method; ii) test generalisability to other disease areas, for which quality of life is the primary objective of management (in stroke, drug dependence and depression), iii) develop and validate a method for translating the most commonly used measure of general health status, the SF-36, into a utility score and iv) illustrate the application of the TTU in comparing intervensions for the prevention and management of depression. The results of the research will be of value to i) decision makers who must compare the performance of medical-health care interventions across a range of diseases and modalities and ii) to clinicians who want to practice evidenced based health care. The potential health gains for the community are substantial, in supporting the redirection of resources to more effective and cost-effectiveRead moreRead less