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Local Sleep In The Awake Brain: An Underlying Cause Of Neurobehavioural Deficits In Sleep Apnea?
Funder
National Health and Medical Research Council
Funding Amount
$582,330.00
Summary
Obstructive sleep apnea (OSA) is a common sleep disorder which significantly impacts daytime functioning leading to excessive sleepiness, and problems with attention and thinking. Currently, the causes for cognitive impairment in OSA (including attentional lapses and performance deficits) are poorly understood. In the awake state, groups of neurons can briefly go “offline” as they do in sleep. These periods of “local sleep” may explain impaired task performance in OSA.
A New Clinical Tool To Assess Fitness-to-drive In Obstructive Sleep Apnea
Funder
National Health and Medical Research Council
Funding Amount
$727,963.00
Summary
Obstructive sleep apnoea (OSA) affects 1 in 4 middle aged adults. OSA results in impaired neurobehavioral function, excessive sleepiness, and more than 2-fold increased motor vehicle crash risk and workplace accidents. However, not all patients are impaired and identifying patients at risk is a daily clinical challenge. This project proposes new and simple measures that can accurately identify patients with OSA who are most vulnerable to alertness failure and motor vehicle accident risk.