Investigation Into The Role Of Regulatory B Cells In Transplantation
Funder
National Health and Medical Research Council
Funding Amount
$400,385.00
Summary
Solid organ transplantation is the most effective therapy for treating organ failure and some cancer. However, a common complication that occurs is graft rejection. The current aim is to develop procedures that reduce the risk of graft rejection without the use of immunosuppressive drugs, which can be toxic and make recipients more susceptible to infection. We are investigating the ability of a cell that is part of the immune system to down-regulate over-reactive immune responses and therefore r ....Solid organ transplantation is the most effective therapy for treating organ failure and some cancer. However, a common complication that occurs is graft rejection. The current aim is to develop procedures that reduce the risk of graft rejection without the use of immunosuppressive drugs, which can be toxic and make recipients more susceptible to infection. We are investigating the ability of a cell that is part of the immune system to down-regulate over-reactive immune responses and therefore reduce rejection.Read moreRead less
Fetal Immune Response To Vertical Transmission Of Toxoplasma Gondii
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
Toxoplasma gondii is a parasite that is a leading cause of human abortion and congenital infections of newborns. In addition, recent research implicates Toxoplasma in diagnoses of schizophrenia and other neuromental conditions. Study of Toxoplasma, it's transmission and effects of infection and development of tools such as vaccines and diagnostic technologies will lead to an improvement in health of mothers, newborns and the wider population.
Early Introduction Of Foods Into Infant Weaning Diets To Induce Oral Tolerance And Prevent Food Allergies.
Funder
National Health and Medical Research Council
Funding Amount
$143,660.00
Summary
Food allergies can be life threatening, and with no treatment, prevention is crucial. Traditional advice for babies whose parents have allergies has been to delay the introduction of allergy causing foods. However, recent research has questioned this approach. In this study I plan to investigate whether the early introduction of fish and eggs in the weaning diet can reduce the incidence of allergy. The results will be crucial to determine the best approach to reduce the risk of food allergy.