First Line Treatments For Common Musculoskeletal Conditions: Establishing Effectiveness And Cost-effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$452,583.00
Summary
Dr Christine Lin is an outstanding young researcher whose research focuses on investigating the effectiveness and cost-effectiveness (value-for-money) of treatments for common musculoskeletal conditions. These conditions, such as back pain and fracture, are a major cause of disability in Australia and abroad. Dr Lin will lead a series of large clinical studies with an aim to improve patient outcomes while minimising the economic burden on the individual, health system and society.
Connecting The Dots: Novel Social Media Technologies For Long-term Functional Recovery In First Episode Psychosis
Funder
National Health and Medical Research Council
Funding Amount
$432,528.00
Summary
The aim of this program of research is to evaluate the effectiveness of innovative online social media and mobile-based interventions purposely designed to improve long-term recovery in youth mental health (i.e., early psychosis and youth depression). These pioneering interventions have been designed by a large multidisciplinary team through the integration of cutting-edge social media technologies, new psychological models and strong consumer-youth participation.
Using Health Economics To Improve Access To Health Care In Under-served Populations
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
Many health care interventions shown to be effective and cost-effective under controlled conditions are consistently under-utilised or mis-used in resource poor settings, especially by the most deprived groups. Over the next 4 years I will establish a program of health economics and health services research to improve the delivery and financing of health care interventions to ensure everyone reaps the benefits of medical science and health technologies and not just those who can afford it.
Technology And Innovation In The Delivery Of Efficient, Effective Treatments For Comorbid Conditions
Funder
National Health and Medical Research Council
Funding Amount
$407,140.00
Summary
Treatment for co-occurring depression and alcohol/other drug use is difficult to access, due to a range of individual and service-level problems. This proposal will build on significant Australian research into psychological treatments for co-occurring problems, by developing and determining the most beneficial, flexible, cost effective models of treatment for these increasingly prevalent problems, regardless of location and ability to access treatment services.
Improving The Prevention And Clinical Management Of Infectious Diseases
Funder
National Health and Medical Research Council
Funding Amount
$236,146.00
Summary
Modern methods of analysis employ complex tools that are not always available or easily understood by doctors making decisions. The dosing of antibiotics is usually constant, even though known factors influence its effectiveness. Similarly, how effective vaccines are can be estimated from routinely available data. This project will develop tools and strategies to assist doctors and public health authorities make the best decisions by improving the analysis of existing data.
Central Blood Pressure: Physiology And Clinical Application
Funder
National Health and Medical Research Council
Funding Amount
$459,270.00
Summary
Current methods used by doctors to measure blood pressure (BP) have many limitations that could result in incorrect diagnosis and inappropriate treatment of high BP (hypertension). This research program will determine the clinical usefulness of new methods to diagnose and treat people with high BP. The underlying mechanisms contributing to high BP will also be examined. The findings will lead to improved ways to identify and more effectively manage people with high BP.
Translating Neuroscience Into Treatments And Public Health Policies For Addictive Behaviours
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
Advances from neuroscience promise to revolutionise our ability to treat and prevent addictive disorders such as gambling, overeating and drug addiction. These developments may also have unexpected clinical consequences, undermine individuals’ belief in their control over their behaviour or increase stigma and discrimination. This project will develop clinical guidelines and public health policy recommendations to ensure that we realise the benefits of neuroscience while minimising social harms.
Application Of Next Generation Sequencing To Address Clinical Problems In Cancer
Funder
National Health and Medical Research Council
Funding Amount
$463,652.00
Summary
Cancer is the cause of 1 in 8 deaths worldwide. Cancer occurs due to errors or mutations in the DNA of normal cells. The mutations may cause the cells to grow incorrectly and become cancer. I will identify the mutations or errors in tumour cells. This will tell us: i) How the tumour started and continued to grow ii) How to treat the tumour cells to kill the cancer The work will involve a variety of cancer types including mesothelioma, melanoma, oesophageal, pancreatic and breast cancer.
Development Of Statistical Methodologies And Application To Clinical Cancer Studies
Funder
National Health and Medical Research Council
Funding Amount
$428,065.00
Summary
Integrating different layers of information coming from the recent ‘-omics’ technologies can help improving the treatment and the prevention of complex diseases. In particular, the identification of molecular markers of different types can be used for better diagnostics and prognosis in cancer and immune diseases. This project will develop innovative statistical solutions to handle and make sense of the vast amount of biological data that are routinely generated in the laboratories.