Real-time imaging of crystal strengthening mechanisms in metals. The strength limit of a metal is marked by rapid motion of crystalline defects. The associated speeds can locally approach that of sound. To probe the associated mechanisms clearly requires both spatial and temporal resolution. We propose to create a new bulk x-ray technique with an unprecedented combination of temporal and spatial resolution. We plan to exploit the technique to mediate a step change in modelling strength based on ....Real-time imaging of crystal strengthening mechanisms in metals. The strength limit of a metal is marked by rapid motion of crystalline defects. The associated speeds can locally approach that of sound. To probe the associated mechanisms clearly requires both spatial and temporal resolution. We propose to create a new bulk x-ray technique with an unprecedented combination of temporal and spatial resolution. We plan to exploit the technique to mediate a step change in modelling strength based on twinning. The formation of crystalline twins is known to dictate the strength of the light metal magnesium. A fuller understanding of the effect of twinning on strength in this metal will provide much needed confidence to implement it more widely in energy saving applications.Read moreRead less
Improving thermal environment of housing for older Australians. This project aims to develop strategies to improve the thermal environment of housing for older Australians based on systematic investigations of the links between weather, thermal comfort, energy use, and well-being. The project will produce evidence-based guidelines and a framework about planning/design issues and operational/behavioural aspects to support older people living independently. Improved thermal conditions will lead to ....Improving thermal environment of housing for older Australians. This project aims to develop strategies to improve the thermal environment of housing for older Australians based on systematic investigations of the links between weather, thermal comfort, energy use, and well-being. The project will produce evidence-based guidelines and a framework about planning/design issues and operational/behavioural aspects to support older people living independently. Improved thermal conditions will lead to better quality of life, reduce the need for institutional care and reduce public health costs. They will also provide environmental benefits through reduced energy use and carbon emissions.Read moreRead less
Visualising molecular level detail in single cells and intact tissues. The goal of this project is to deliver a new toolkit for imaging cells at an unprecedented resolution and level of chemical detail. We will expand the capabilities of two existing, but complementary, methods: optical fluorescence microscopy with responsive probes and X-ray fluorescence imaging. Expected outcomes include improved techniques and benchmarks for visualising bacterial and mammalian cells; development of new molecu ....Visualising molecular level detail in single cells and intact tissues. The goal of this project is to deliver a new toolkit for imaging cells at an unprecedented resolution and level of chemical detail. We will expand the capabilities of two existing, but complementary, methods: optical fluorescence microscopy with responsive probes and X-ray fluorescence imaging. Expected outcomes include improved techniques and benchmarks for visualising bacterial and mammalian cells; development of new molecules for elucidating cellular chemistry; better utilisation of valuable synchrotron resources; and greater understanding of the strengths and limitations of current microscopy workflows. Results should benefit the biotechnology sector, and may lead to improved medical, diagnostic, and bioremediation capacity.Read moreRead less
X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect t ....X-ray Ghost Imaging and Tomography. This project aims to achieve safer, faster, and cheaper 3D X-ray imaging through a technique known as ghost imaging. X-ray imaging provides valuable information about internal structures, however, X-rays are carcinogenic and exposure (or dose) should be limited. Ghost imaging is an unconventional technique developed with visible light that has many potential benefits over conventional imaging. This research group are world leaders in ghost imaging and expect to develop software and hardware techniques to realise its potential and extend it to ghost tomography. The focus of this project is on reducing cancer risk in medical imaging, and allowing real-time quality control for 3D printing in safety-critical industries such as aerospace.Read moreRead less
Characterisation of the beneficial vs toxic forms of selenium in the diet. This project aims to examine how dietary selenium is converted into essential proteins and beneficial compounds that mitigate against a broad range of human diseases; or alternatively, into toxic molecules. Cutting-edge methodologies should resolve significant unknowns in selenium metabolism, to provide definitive dietary guidelines and to explore how selenium can treat and protect against disease. Expected outcomes from ....Characterisation of the beneficial vs toxic forms of selenium in the diet. This project aims to examine how dietary selenium is converted into essential proteins and beneficial compounds that mitigate against a broad range of human diseases; or alternatively, into toxic molecules. Cutting-edge methodologies should resolve significant unknowns in selenium metabolism, to provide definitive dietary guidelines and to explore how selenium can treat and protect against disease. Expected outcomes from this national and international collaboration include expert training for young biochemical researchers and refinements to novel analytical techniques. Results should benefit the food and agricultural sectors to provide tailored products locally and for export, as well as enhanced health opportunities for all Australians.Read moreRead less
Quantum thermalisation: a new framework for nuclear collisions. This project aims to quantify and model the processes that lead to quantum thermalisation in nuclear collisions. Thermalisation is critical to the synthesis of new superheavy elements, production of medical isotopes, and creation of heavy elements in the cosmos. Yet quantum thermalisation in nuclear systems is not understood, causing models to be wrong by up to a factor of 100. This project will determine the routes to thermalisatio ....Quantum thermalisation: a new framework for nuclear collisions. This project aims to quantify and model the processes that lead to quantum thermalisation in nuclear collisions. Thermalisation is critical to the synthesis of new superheavy elements, production of medical isotopes, and creation of heavy elements in the cosmos. Yet quantum thermalisation in nuclear systems is not understood, causing models to be wrong by up to a factor of 100. This project will determine the routes to thermalisation in nuclear systems by combining the latest concepts in many body quantum physics with enhancements to Australia’s precision measurement capabilities. The project will enable new fundamental tests of quantum mechanics and benefit broader applications of nuclear collisions.Read moreRead less
Probing nanoscale disorder in 3D with x-ray free-electron lasers. This project aims to reveal the 3D nanostructure of disordered matter with x-rays for the first time. Existing x-ray scattering techniques for disordered structures currently provide limited, one-dimensional information only. The expected outcomes of the project include an enhanced new capability for the Australian Synchrotron and international x-ray laser facilities, and new insights into the microscopic origins of the properties ....Probing nanoscale disorder in 3D with x-ray free-electron lasers. This project aims to reveal the 3D nanostructure of disordered matter with x-rays for the first time. Existing x-ray scattering techniques for disordered structures currently provide limited, one-dimensional information only. The expected outcomes of the project include an enhanced new capability for the Australian Synchrotron and international x-ray laser facilities, and new insights into the microscopic origins of the properties of liquids and biological membranes. This should benefit research areas that use x-ray scattering to probe the nanostructure of materials for diverse applications such as nanotechnology, fuel cells and drug design.Read moreRead less
Resonant tender X-ray scattering of organic semiconductors. This project aims to establish resonant tender X-ray scattering as a mature technique for unravelling the complex microstructure of organic semiconductor layers. By understanding and exploiting the resonant interaction between organic semiconductors and X-rays tuned to appropriate absorption edges, new information about the molecular packing of these materials will be obtained. The expected outcomes are new experimental methodologies an ....Resonant tender X-ray scattering of organic semiconductors. This project aims to establish resonant tender X-ray scattering as a mature technique for unravelling the complex microstructure of organic semiconductor layers. By understanding and exploiting the resonant interaction between organic semiconductors and X-rays tuned to appropriate absorption edges, new information about the molecular packing of these materials will be obtained. The expected outcomes are new experimental methodologies and analysis tools for determining the complex structure of technologically relevant materials. Benefits include understanding of the properties of solution-processed semiconductors enabling the design of high performance materials with applications in energy, electronics, lighting and health.Read moreRead less