Plasma Exchange And Glucocorticoids In Anti-neutrophil Cytoplasm Antibody Associated Systemic Vasculitis: A Randomised Controlled Trial (PEXIVAS Australia)
Funder
National Health and Medical Research Council
Funding Amount
$420,110.00
Summary
ANCA-associated vasculitis is a life-threatening disease. The PEXIVAS trial will investigate whether plasma exchange, in addition to immunosuppressive therapy and glucocorticoids, will reduce death and the development of severe kidney failure due to this disease. Additionally, the project will also look at whether using a reduced dose of glucocorticoids is just as effective as larger doses in lessening the infectious complications of treatment.
The Clinical Effectiveness Of A Simple New Treatment For Supine-dependent Obstructive Sleep Apnoea
Funder
National Health and Medical Research Council
Funding Amount
$529,178.00
Summary
Obstructive sleep apnoea is a common and debilitating breathing problem in sleep with serious effects on sleep and health. A third of patients could be very simply treated by avoiding sleeping on their back. Existing treatments are uncomfortable, often not used and better options are needed. This project will test symptom relief and treatment adherence with a new comfortable low cost supine avoidance therapy against current best practice treatment.
Improving Maternal And Infant Outcomes: A Multicentre Randomised Controlled Trial Of Midwifery And Dental Intervention
Funder
National Health and Medical Research Council
Funding Amount
$457,724.00
Summary
Poor oral health during pregnancy can impact the health of the mother and baby. Yet, many expectant mothers are unaware of the implications of poor oral health. In Australia there is a lack of importance being placed on maternal oral health. The aim of this study is to determine the effectiveness of a new service which will promote maternal oral health through collaboration between midwives and dentists. We expect the new service will improve women's oral health, uptake of dental services and po ....Poor oral health during pregnancy can impact the health of the mother and baby. Yet, many expectant mothers are unaware of the implications of poor oral health. In Australia there is a lack of importance being placed on maternal oral health. The aim of this study is to determine the effectiveness of a new service which will promote maternal oral health through collaboration between midwives and dentists. We expect the new service will improve women's oral health, uptake of dental services and potentially improve pregnancy outcomes.Read moreRead less
Randomised Control Trial Of Effectiveness Of Silver Fluoride In Managing Deciduous Dental Caries In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$695,220.00
Summary
This study seeks to test a non-invasive treatment for dental decay in young children which may prevent the progression of the decay further into the tooth. This treatment is currently used in some areas. Dental decay is very common in young children in remote communities where access to dental care is often limited. The treatment may reduce pain and oral and facial infections sometimes leading to hospitalisation.
The Central Australian Heart Protection Study: A Randomised Trial Of Nurse-Led, Family Based Secondary Prevention Of Acute Coronary Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$1,923,630.00
Summary
Despite the high burden of cardiovascular diseases among Indigenous Australians, few intervention trials have sought to evaluate novel approaches to reducing differential outcomes in this vulnerable group. The Central Australian Heart Protection Study seeks to test the effectiveness of a nurse-led, family based education and assessment program in reducing the incidence of poor outcomes in indigenous and non-indigenous patient’s following an Acute Coronary Syndrome (ACS).