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A Randomised Stepped Wedge Trial Of The Scaling Up Of A Community Based Alcohol Education Program In Rural Sri Lankan Villages And Its Effects On Alcohol Use, And Associated Harms, Depression And Social Capital.
Funder
National Health and Medical Research Council
Funding Amount
$825,364.00
Summary
Alcohol use is major problem in much of rural Asia. In addition to direct effects on health it is major contributor to suicide, domestic violence and poverty. Much of the alcohol consumed is illicit and so consumption is not influenced by regulation or taxation. This is a trial of a community intervention in rural Sri Lanka to reduce alcohol use and alcohol related disorders that uses participatory drama in conjunction with previously trialed educational materials.
The Extinction Of Conditioned Fear And Its Implications For Cue Exposure Therapy
Funder
National Health and Medical Research Council
Funding Amount
$322,430.00
Summary
This project studies extinction of Pavlovian conditioned fear reactions in rats. Extinction of these reactions is an animal model for exposure therapy used in the treatment of anxiety disorders in people. In exposure therapy, the patient, aided by the clinician, confronts trauma-related cues in the absence of any overt danger. The intention of this therapy is to reduce the ability of the trauma-related cues to provoke the fear reactions that are undermining the patient's quality of life. In Pavl ....This project studies extinction of Pavlovian conditioned fear reactions in rats. Extinction of these reactions is an animal model for exposure therapy used in the treatment of anxiety disorders in people. In exposure therapy, the patient, aided by the clinician, confronts trauma-related cues in the absence of any overt danger. The intention of this therapy is to reduce the ability of the trauma-related cues to provoke the fear reactions that are undermining the patient's quality of life. In Pavlovian conditioning, subjects (typically rats) are exposed to a signaling relation between an initially neutral stimulus (e.g., a noise) and a feared outcome (e.g., foot shock). When later repeatedly exposed to the initially neutral but now feared stimulus (the noise) in the absence of the feared outcome, the fear reactions it acquired progressively decline until eventually it fails to elicit any such reactions. The fear reactions are said to have been extinguished. There has been significant progress in understanding the psychological processes and neural mechanisms underlying the acquisition of fear reactions, but much less is known about the processes and mechanisms underlying the extinction of these reactions. The project has two general objectives. The first is to determine the conditions of extinction training that promote long-term loss of fear reactions. The second objective is to determine how the brain controls this extinction of learned fear. Achieving these aims will be significant for two reasons. First, it will contribute to understanding the mechanisms by which animals (including people) learn to adjust their behaviour to bring it into line with the current relations that exist between events in the world. Second, it will provide important information about how such adjustment is facilitated or impaired across extinction training and, thereby, contribute towards understanding both the successes and failures of cue exposure therapy for fear-related disorders.Read moreRead less
The effect of cochlear implants on cognitive decline in ageing Australians. This project aims to investigate the impact of cochlear implants on cognitive function in elderly people with deafness. Deafness has been found to be independently associated with a 30–40 per cent accelerated rate of cognitive decline in elderly adults. There is currently no effective treatment for cognitive decline. The intended outcomes of this observational study will help us to understand the biological process of co ....The effect of cochlear implants on cognitive decline in ageing Australians. This project aims to investigate the impact of cochlear implants on cognitive function in elderly people with deafness. Deafness has been found to be independently associated with a 30–40 per cent accelerated rate of cognitive decline in elderly adults. There is currently no effective treatment for cognitive decline. The intended outcomes of this observational study will help us to understand the biological process of cognitive decline, whether hearing loss is causal, and whether the process can be altered. These findings should be applicable to all individuals with hearing loss. If cochlear implants delay cognitive decline, this would significantly affect policy, quality of life for the elderly, and the cost to society.Read moreRead less
An evaluation of concerns, self-perceived needs, and supportive interventions, for informal cancer carers: A comparative study of female and male carers. Informal cancer carers experience high levels of anxiety, depression, and unmet support needs, with women carers at higher risk than men. However, little is known about the factors underlying this gender difference, and existing support services have not specifically targeted the needs of female and male cancer carers. This study will explore t ....An evaluation of concerns, self-perceived needs, and supportive interventions, for informal cancer carers: A comparative study of female and male carers. Informal cancer carers experience high levels of anxiety, depression, and unmet support needs, with women carers at higher risk than men. However, little is known about the factors underlying this gender difference, and existing support services have not specifically targeted the needs of female and male cancer carers. This study will explore the concerns, self-perceived needs, and psychological wellbeing of informal cancer carers living in New South Wales, comparing the experiences of female and male carers, at different stages of the care-giving journey. Based on these findings, a program of targeted supportive interventions will be developed, and then systematically evaluated within a controlled trial.Read moreRead less
Meeting the needs of cancer support group leaders. Social support plays a pivotal role in the psychological adjustment of people with cancer. Support groups provide unique input, but their outcomes are reliant on the quality and sustainability of the leaders. Internationally, little is known about the challenges and unmet needs of cancer support group leaders, or how to best support them. This study will:
a) clarify the needs of cancer group leaders
b) design and evaluate two interventions (mi ....Meeting the needs of cancer support group leaders. Social support plays a pivotal role in the psychological adjustment of people with cancer. Support groups provide unique input, but their outcomes are reliant on the quality and sustainability of the leaders. Internationally, little is known about the challenges and unmet needs of cancer support group leaders, or how to best support them. This study will:
a) clarify the needs of cancer group leaders
b) design and evaluate two interventions (minimal and intense) to meet the needs of leaders.
If successful, this study will provide the evidence on which cancer organizations around the world can base interventions to sustain cancer support group leaders and thus hopefully improve psychological outcomes for cancer patients and their carers.Read moreRead less