Discovery Early Career Researcher Award - Grant ID: DE230100178
Funder
Australian Research Council
Funding Amount
$453,913.00
Summary
Fast, lightweight and live nanopore sequencing analysis. This project aims to address limitations in nanopore sequencing (latest emerging technology in genomics) by applying advanced computational methods. This project expects to create new knowledge in bioinformatics and computer science through innovative approaches that leverage the live data streaming capability of nanopore devices to deliver results rapidly, or in real-time. Expected outcomes include improved, highly efficient analysis meth ....Fast, lightweight and live nanopore sequencing analysis. This project aims to address limitations in nanopore sequencing (latest emerging technology in genomics) by applying advanced computational methods. This project expects to create new knowledge in bioinformatics and computer science through innovative approaches that leverage the live data streaming capability of nanopore devices to deliver results rapidly, or in real-time. Expected outcomes include improved, highly efficient analysis methods and designs for future creation of custom computer hardware for nanopore analysis. This will facilitate widespread adoption of nanopore technology in bioscience research and applied domains (health, agriculture, ecology, biosecurity and forensics), including for portable in-the-field applications. Read moreRead less
Trust-Oriented Data Analytics in Online Social Networks. Trust-oriented data analytics is essential in online social networks for reducing deceitful interactions and enhancing trust between users. This project aims to systematically devise innovative solutions by considering rich social contextual information as an important source of trust. The expected outcomes of this project include innovative solutions from a fundamental perspective to the challenges of context-aware trust propagation, trus ....Trust-Oriented Data Analytics in Online Social Networks. Trust-oriented data analytics is essential in online social networks for reducing deceitful interactions and enhancing trust between users. This project aims to systematically devise innovative solutions by considering rich social contextual information as an important source of trust. The expected outcomes of this project include innovative solutions from a fundamental perspective to the challenges of context-aware trust propagation, trust network searching/matching, and trustworthy/malicious user prediction in online social networks. This project is significant as it will advance the knowledge base for enabling a trustworthy social networking environment, benefiting billions of Australian and worldwide online social network users.Read moreRead less
Brain-skull interface: discovering the missing piece of head biomechanics. Overall objective of this project is to measure, mathematically describe and implement in software mechanical properties of brain-skull interface – a critical component of current large and sophisticated computational models of the brain and the last missing piece of brain biomechanics knowledge. This will allow increased reliability of comprehensive biomechanical models used to simulate realistic injury and surgery scena ....Brain-skull interface: discovering the missing piece of head biomechanics. Overall objective of this project is to measure, mathematically describe and implement in software mechanical properties of brain-skull interface – a critical component of current large and sophisticated computational models of the brain and the last missing piece of brain biomechanics knowledge. This will allow increased reliability of comprehensive biomechanical models used to simulate realistic injury and surgery scenarios.
The problem is significant and urgent. Every year in Australia, there are over 22,000 cases of traumatic brain injury, some of which could be prevented by better passive and active countermeasures; and over 12,000 neurosurgical procedures that surgical simulation could make more accurate and therefore safer.Read moreRead less
Internet Timing for the Ages: Establishing the New Timekeeping System. All computers incorporate a software clock, essential to myriad software applications. An economic way to synchronize such clocks is over a network, however the approach the Internet currently depends upon is unreliable and vulnerable. This project aims to establish a new architecture for networked timekeeping, built on future-proofed fundamentals, that will for the first time address each of accuracy, reliability, and trust. ....Internet Timing for the Ages: Establishing the New Timekeeping System. All computers incorporate a software clock, essential to myriad software applications. An economic way to synchronize such clocks is over a network, however the approach the Internet currently depends upon is unreliable and vulnerable. This project aims to establish a new architecture for networked timekeeping, built on future-proofed fundamentals, that will for the first time address each of accuracy, reliability, and trust. The expected outcome is a national prototype, serving the public with accurate and trusted time, that will form the basis of the next generation timekeeping system for the Internet and the Internet of Things. Expected benefits include enhanced productivity across the digital economy, and resilience to GPS failures.Read moreRead less
Embracing Changes for Responsive Video-sharing Services. Video-sharing platforms are a critical information channel for the public. Increasing scale and shifts in user base, with Generation Z now as the dominant user, have resulted in an unprecedented amount of ubiquitous changes in the content and users of these platforms which greatly challenges the responsiveness and quality of the services provided. This project aims to design innovative algorithms to effectively predict and leverage changes ....Embracing Changes for Responsive Video-sharing Services. Video-sharing platforms are a critical information channel for the public. Increasing scale and shifts in user base, with Generation Z now as the dominant user, have resulted in an unprecedented amount of ubiquitous changes in the content and users of these platforms which greatly challenges the responsiveness and quality of the services provided. This project aims to design innovative algorithms to effectively predict and leverage changes, optimise the value of changes, and extract insights from changes for diverse downstream applications of video-sharing platforms. The expected outcomes will create new-generation representation learning techniques, and provide practical tools to amplify the socioeconomic values of video-sharing platforms.Read moreRead less
Simulating chemical reactions on quantum computers. This project aims to enable a new capability for simulating practically relevant chemical dynamics and reactivity in regimes where conventional computational chemistry fails. It expects to do so by generating an extensive toolbox of quantum algorithms that would allow quantum computers to carry out otherwise intractable simulations of a wide range of chemical processes using existing quantum devices. As quantum technology matures, these algorit ....Simulating chemical reactions on quantum computers. This project aims to enable a new capability for simulating practically relevant chemical dynamics and reactivity in regimes where conventional computational chemistry fails. It expects to do so by generating an extensive toolbox of quantum algorithms that would allow quantum computers to carry out otherwise intractable simulations of a wide range of chemical processes using existing quantum devices. As quantum technology matures, these algorithms should enable quantum computers to accelerate computational screening of new chemical processes in a wide range of fields, enabling faster discovery of, for example, improved catalysts, batteries, medicines, fuels, and solar cells.Read moreRead less
Custom Computing for DNA Analysis of Third Generation Sequencers. The project aims to create a Domain Specific Computing System to analyse data emerging from third-generation DNA sequencers. The significance is that such a system will enable in-situ analysis, facilitating far wider deployment of modern DNA technologies. The expected outcome will be a portable low-power computing system containing custom instructions, custom cache configurations, and custom architectures. Benefits include: 1. d ....Custom Computing for DNA Analysis of Third Generation Sequencers. The project aims to create a Domain Specific Computing System to analyse data emerging from third-generation DNA sequencers. The significance is that such a system will enable in-situ analysis, facilitating far wider deployment of modern DNA technologies. The expected outcome will be a portable low-power computing system containing custom instructions, custom cache configurations, and custom architectures. Benefits include: 1. deployment of DNA analysis techniques in remote areas and in places without large servers and access to high-speed networks connecting to cloud servers; 2. quicker analysis enabling rapid response, cheaper, portable systems; and, 3. training for a cohort of research and honours students.Read moreRead less