Health And Fertility Of Young Men Conceived Using Intra-cytoplasmic Sperm Injection
Funder
National Health and Medical Research Council
Funding Amount
$362,570.00
Summary
The injection of a single sperm into the egg (ICSI) has been the main IVF treatment for men with poor sperm quality since 1993 but is now often used for other types of infertility. Concern has been raised about the health of the children. We will approach >800 parents and their adult sons conceived using ICSI and will assess his general health and development, and fertility. This work will improve patient counselling and practice guidelines, and direct research into the safety of ICSI.
Clinical Review Of A Cohort Aged 22-33 Years Conceived Using Assisted Reproductive Technologies
Funder
National Health and Medical Research Council
Funding Amount
$946,454.00
Summary
In a recent study, using telephone-interviews, we compared the health and wellbeing of 547 singleton young adults born following assisted reproductive technologies (ART), with 549 matched controls. Reviewing their health when they are 22-33 years is possible because of their ongoing interest. We have a protocol in place to measure their cardiac and respiratory function and other aspects of growth and development. Our findings will fill a major knowledge gap about the longer term safety of ART.
Finding and exploiting interesting paths in multidimensional information spaces. This project will invent a new approach for searching within a large complex information space, finding interesting paths between points within the space, visualising the results, and supporting rich, human-centric user interaction with queries and results. This project will embody these techniques in a novel, internet-scale framework to support rapid development of large path search and visualisation applications. ....Finding and exploiting interesting paths in multidimensional information spaces. This project will invent a new approach for searching within a large complex information space, finding interesting paths between points within the space, visualising the results, and supporting rich, human-centric user interaction with queries and results. This project will embody these techniques in a novel, internet-scale framework to support rapid development of large path search and visualisation applications. Evaluation will be via development of several exemplar applications. The techniques and framework will be applicable to a broad range of economically important problems in areas as diverse as health, travel, scientific publication search, product marketing and software engineering.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775582
Funder
Australian Research Council
Funding Amount
$530,000.00
Summary
Data Grid -- Access Layer. Vast increases in computing power and the arrival of new scientific instruments are contributing to the so-called data deluge of the 21st century. Accessing and archiving these data is essential to research. While the underlying computing and network requirements are well resourced, data access has been relatively neglected in Australia. A continuing problem in Australian research communities is the absence of coordinated access to digital storage resources. In many ca ....Data Grid -- Access Layer. Vast increases in computing power and the arrival of new scientific instruments are contributing to the so-called data deluge of the 21st century. Accessing and archiving these data is essential to research. While the underlying computing and network requirements are well resourced, data access has been relatively neglected in Australia. A continuing problem in Australian research communities is the absence of coordinated access to digital storage resources. In many cases computational and experimental data are stored on ad-hoc resources, such as local university servers, PC disc drives, and are not generally accessible. The central goal of this proposal is to provide access to an integrated scientific data storage capacity for Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668445
Funder
Australian Research Council
Funding Amount
$800,000.00
Summary
Data Grid Storage Infrastructure for e-Research. Vast increases in computing power and the arrival of new scientific instruments are contributing to the so-called data deluge of the 21st century. Archiving these data is essential to research. While the underlying computing and network requirements are well resourced, data storage capacity has been relatively neglected in Australia. A continuing problem in Australian research communities is the absence of coordinated digital storage resources. In ....Data Grid Storage Infrastructure for e-Research. Vast increases in computing power and the arrival of new scientific instruments are contributing to the so-called data deluge of the 21st century. Archiving these data is essential to research. While the underlying computing and network requirements are well resourced, data storage capacity has been relatively neglected in Australia. A continuing problem in Australian research communities is the absence of coordinated digital storage resources. In many cases computational and experimental data are stored on ad-hoc resources, such as local university servers, PC disc drives, CDs, or DVDs, and are not generally accessible. The central goal of this proposal is to provide a long-term, integrated scientific data storage capacity for Australia. Read moreRead less
Semantic Vectorisation: From Bitmaps to Intelligent Representations. The objective of this innovative project is to provide a solution to the open question of representing natural images by semantically rich vector graphics. The challenges are to identify key visual and temporal elements for images and videos, and efficiently decompose the visual data into semantic vector representations that are faithful to original data, compact and editable. The project aims to investigate new bitmap-to-vecto ....Semantic Vectorisation: From Bitmaps to Intelligent Representations. The objective of this innovative project is to provide a solution to the open question of representing natural images by semantically rich vector graphics. The challenges are to identify key visual and temporal elements for images and videos, and efficiently decompose the visual data into semantic vector representations that are faithful to original data, compact and editable. The project aims to investigate new bitmap-to-vector conversion methods. It is expected to develop a framework where semantic labels and hyperlinks can be embedded in visual data automatically. It hopes to pioneer the creation of a web of images where the links are on image/video regions. New image simplification, stylisation, and non-photorealistic rendering methods are expected to be provided.Read moreRead less
Reducing The Greatest Uncertainty In Radiotherapy.
Funder
National Health and Medical Research Council
Funding Amount
$594,197.00
Summary
The weakest link in radiotherapy is defining treatment volumes (contouring). Lack of accuracy and consistency in clinical trial contouring has been shown to result in reduced patient outcomes. Manual review of contouring is resource intensive, expensive and for advanced treatments unachievable in a timely fashion. We will assess an automated approach to contouring assessment using 4 clinical trial datasets, changing practice for future studies and enabling consistent assessment in the clinic.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100090
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
Computational infrastructure for developing deep machine learning models. Computational infrastructure for developing deep machine learning models:
The computational infrastructure for developing deep machine learning models aims to enable new developments in machine learning of deep neural network models by providing the specialised computing necessary to train and evaluate the networks. In the last three years, deep networks have smashed previous performance ceilings for tasks such as object ....Computational infrastructure for developing deep machine learning models. Computational infrastructure for developing deep machine learning models:
The computational infrastructure for developing deep machine learning models aims to enable new developments in machine learning of deep neural network models by providing the specialised computing necessary to train and evaluate the networks. In the last three years, deep networks have smashed previous performance ceilings for tasks such as object recognition in images, speech recognition and automatic translation, bringing the prospect of machine intelligence closer than ever. Modern machine learning techniques have had huge impact in the last decade in fields such as robotics, computer vision and data analytics. The facility would enable Australian researchers to develop, learn and apply deep networks to problems of national importance in robotic vision and big data analytics. Read moreRead less
A theoretical framework for practical partial fingerprint identification. Fingerprints captured from a crime scene are often partial and poor quality which makes it difficult to identify the criminal suspects from large databases. This project will find mathematical models which can estimate the missing information located in the blank areas of a partial fingerprint and effectively identify it.