Patient-specific Computational Tools for Diagnosing and Treating Gait Disorders in Children with Cerebral Palsy. This proposal addresses one of the most fundamental and difficult questions related to the treatment of children with cerebral palsy: Why do these children walk in a crouched position, with excessively bent hips and knees? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the outcomes of orthopaedic surgeries ....Patient-specific Computational Tools for Diagnosing and Treating Gait Disorders in Children with Cerebral Palsy. This proposal addresses one of the most fundamental and difficult questions related to the treatment of children with cerebral palsy: Why do these children walk in a crouched position, with excessively bent hips and knees? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the outcomes of orthopaedic surgeries designed to correct movement abnormalities in these patients. Realistic computer simulations of human movement can play a pivotal role in healthcare through patient rehabilitation; in sports, through the development of personalized training programs for elite athletes; and in entertainment, through the creation of video games and animated films.Read moreRead less
Large-scale three dimensional deformation of the lithosphere by subduction and mantle flow. We will be modelling of the dynamics of the Earth's crust and shallow lithosphere in response to the huge stresses created by plate motions. For Australia these stresses are transmitted from the distant plate boundaries, but they have a direct controlling influence on the evolution of the petroleum rich basins of Australia. These basins have reached maturity; further exploration will be in deep water wher ....Large-scale three dimensional deformation of the lithosphere by subduction and mantle flow. We will be modelling of the dynamics of the Earth's crust and shallow lithosphere in response to the huge stresses created by plate motions. For Australia these stresses are transmitted from the distant plate boundaries, but they have a direct controlling influence on the evolution of the petroleum rich basins of Australia. These basins have reached maturity; further exploration will be in deep water where geophysical prospecting methods are unreliable. Model-driven "exploration geodynamics" methods such as those we are developing will be needed to support traditional exploration techniques in these areas.Read moreRead less
THE DEVELOPMENT OF MECHANISTIC MODELS FOR BUBBLY FLOWS WITH HEAT AND MASS TRANSFER. Commercially available CFD computer codes are currently widely used in many Australian industrial sectors. It is clearly recognised that the state-of-the-art models for dealing with complex bubbly flows with/without heat and mass transfer in these computer codes require further developments and improvements. This research project will address the prevalent deficiency in many of these computer codes. It is antici ....THE DEVELOPMENT OF MECHANISTIC MODELS FOR BUBBLY FLOWS WITH HEAT AND MASS TRANSFER. Commercially available CFD computer codes are currently widely used in many Australian industrial sectors. It is clearly recognised that the state-of-the-art models for dealing with complex bubbly flows with/without heat and mass transfer in these computer codes require further developments and improvements. This research project will address the prevalent deficiency in many of these computer codes. It is anticipated that through this major development of new models capable of predicting a wide range of industrial bubbly flow problems and implementation thereafter in these computer codes, industries will experience significant benefits especially reduce time and costs in their design and production.Read moreRead less
Experimental and Numerical Modelling of Gas-Liquid Flows. Multiphase flow systems are encountered in many process industries such as chemical, petroleum, mining, energy, food and pharmaceutical, which are fundamental to the Australian economy. Commercially available computer codes for simulating such systems are currently widely used in many Australian industrial sectors. This research project will address the prevalent deficiency in many of these computer codes and develop new models capable of ....Experimental and Numerical Modelling of Gas-Liquid Flows. Multiphase flow systems are encountered in many process industries such as chemical, petroleum, mining, energy, food and pharmaceutical, which are fundamental to the Australian economy. Commercially available computer codes for simulating such systems are currently widely used in many Australian industrial sectors. This research project will address the prevalent deficiency in many of these computer codes and develop new models capable of predicting a wide range of industrial bubbly flow problems. The resultant improved computer codes will provide industries with significant benefits - especially reduced times and costs in their design and production.Read moreRead less
Three dimensional computational models of geological basin and hinterland evolution incorporating lithospheric mantle and surface processes. Petroleum exploration in deepwater areas offshore Australia is becoming increasingly important as more accessible, shallow water oil reserves near exhaustion. Geological simulation is an important tool for understanding deep water basins where geophysical imaging techniques are less effective. This project will develop 3D computational models relevant to un ....Three dimensional computational models of geological basin and hinterland evolution incorporating lithospheric mantle and surface processes. Petroleum exploration in deepwater areas offshore Australia is becoming increasingly important as more accessible, shallow water oil reserves near exhaustion. Geological simulation is an important tool for understanding deep water basins where geophysical imaging techniques are less effective. This project will develop 3D computational models relevant to understanding the development and evolution of geological basins and the sediments that fill them. The models will be integrated with available offshore data for potentially prospective Australian basins in the Northwest Shelf and the Southern Australian margin.Read moreRead less
Non-invasive assessment of hip fracture risk in elderly people. No falls, no fractures - this will be the main benefit of the proposed research. The most significant outcome will be new computational tools to improve current understanding of the biomechanics of falls and bone fragility in elderly people, which, in turn, will help to reduce healthcare costs associated with the treatment and management of hip fractures. Realistic models and computer simulations of human movement can play a pivota ....Non-invasive assessment of hip fracture risk in elderly people. No falls, no fractures - this will be the main benefit of the proposed research. The most significant outcome will be new computational tools to improve current understanding of the biomechanics of falls and bone fragility in elderly people, which, in turn, will help to reduce healthcare costs associated with the treatment and management of hip fractures. Realistic models and computer simulations of human movement can play a pivotal role in three of Australia's largest industries: healthcare, through the diagnosis and treatment of movement disorders; sports, through the development of personalized training programs for elite athletes; and entertainment, through the development of video/digital games and animated films.Read moreRead less
A Control Systems Approach for Understanding Human Locomotion. This proposal addresses fundamental, difficult questions in the context of human movement: How do muscles move our limbs during walking? How do the nervous system and muscles work together to control movement? Realistic computer simulations of human movement can help answer these questions and, in so doing, can play a pivotal role in three of Australia's largest industries: healthcare, through clinical gait analysis and gait rehabili ....A Control Systems Approach for Understanding Human Locomotion. This proposal addresses fundamental, difficult questions in the context of human movement: How do muscles move our limbs during walking? How do the nervous system and muscles work together to control movement? Realistic computer simulations of human movement can help answer these questions and, in so doing, can play a pivotal role in three of Australia's largest industries: healthcare, through clinical gait analysis and gait rehabilitation (diagnosis and treatment of movement disorders); sports, through the development of personalized training programs for elite athletes; and entertainment, through the development of video/digital games and animated films (creation of virtual life-like actors).Read moreRead less
Patient-specific computational tools for evaluating functional performance of total knee replacements in vivo. Knee replacement surgery is the established treatment for end-stage osteoarthritis. This proposal addresses one of the most fundamental questions related to knee replacement surgery: Why do total knee replacements fail? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the functional performance and longevity o ....Patient-specific computational tools for evaluating functional performance of total knee replacements in vivo. Knee replacement surgery is the established treatment for end-stage osteoarthritis. This proposal addresses one of the most fundamental questions related to knee replacement surgery: Why do total knee replacements fail? High-fidelity, patient-specific computer simulations of walking can help to answer this question and, in so doing, can improve the functional performance and longevity of current knee implant designs. Realistic computer simulations of human movement also can play a pivotal role in healthcare through patient rehabilitation; in sports, through the development of personalized training programs for elite athletes; and in entertainment, through the creation of video games and animated films.Read moreRead less
The Initiation and 3D Evolution of Instabilities in the Deep Continental Lithosphere. This project is part of a new international initiative in the Geodynamics of the Australian Plate bringing together studies of the active tectonics of the boundary regions of our plate and the ancient analogues of these processes which are locked into the stable interior of the Australian continent. The proposed research is a good fit to the Identification and Extraction of Deep Earth Resources priority goal. D ....The Initiation and 3D Evolution of Instabilities in the Deep Continental Lithosphere. This project is part of a new international initiative in the Geodynamics of the Australian Plate bringing together studies of the active tectonics of the boundary regions of our plate and the ancient analogues of these processes which are locked into the stable interior of the Australian continent. The proposed research is a good fit to the Identification and Extraction of Deep Earth Resources priority goal. Detachment of the lithosphere is associated with fertile mantle being emplaced at shallow depth below the crust; an important precursory event for mineralization. The project builds upon AuScope (NCRIS 5.13) to create infrastructure for a new, smart resource exploration and extraction industry based on modelling and simulation.Read moreRead less
Special Research Initiatives - Grant ID: SR0354793
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
A Neural Network: Understanding Brain Function. This proposal focuses on the mechanisms that regulate brain function, particularly those underpinning the changes in circuitry (plasticity) caused by altered inputs. As such, its core goal is to create an interface between researchers in the neurosciences, computational modelling, robotics and cognitive sciences in order to facilitate optimum collaborative interactions, identify key research questions and promote training opportunities across a mul ....A Neural Network: Understanding Brain Function. This proposal focuses on the mechanisms that regulate brain function, particularly those underpinning the changes in circuitry (plasticity) caused by altered inputs. As such, its core goal is to create an interface between researchers in the neurosciences, computational modelling, robotics and cognitive sciences in order to facilitate optimum collaborative interactions, identify key research questions and promote training opportunities across a multidisciplinary spectrum. This will drive an integrated and accelerated program of discovery and technological development, enhancing Australia's leadership in this crucial field and helping to highlight new biotechnology opportunities and capture social and economic benefits for the nation. Read moreRead less