3D Histological And MRI Atlases Of Brain And Spinal Cord For Research And Clinical Practice
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
This project uses imaging techniques to produce the next generation of maps of the central nervous system. It will advance our understanding of the organisation and structure of the brain and spinal cord of humans and experimental animals, paving the way for the development of psychotherapeutic drugs and more accurate interventions on the human brain. The new maps will help those who study the brain of patients with diseases such as Alzheimer’s, Parkinson’s or animal models of these diseases.
Imaging Atlases Of The Brain Of Humans And Experimental Animals
Funder
National Health and Medical Research Council
Funding Amount
$808,375.00
Summary
This project uses imaging techniques and molecular genetics to produce the next generation of brain maps. It will advance our understanding of the organisation and structure of the brain and spinal cord of humans and experimental animals – paving the way for the development of psychotherapeutic drugs and more accurate interventions on the human brain. The new maps will help those who study the brain of patients with diseases such as Alzheimer’s or Parkinson’s or animal models of these diseases.
Applying Next Generation Sequencing To Family Studies
Funder
National Health and Medical Research Council
Funding Amount
$182,622.00
Summary
Recent advances in technology can determine the DNA composition of a person for much longer stretches of DNA, at a much cheaper cost. I use statistical analysis to identify regions of the human genome that harbour mutations that cause diseases such as epilepsy in families. These regions contain 5-15 million base pairs. We need to find the ONE base pair that causes disease. This application deals with the development of new tools to exploit new technology for the identification of mutations.
This fellowship supports continuing work on statistical methods and applications for the detection and characterization of genes involved in complex diseases, notably melanoma, but a number of related characteristics such as skin hair and eye colour, moles and freckling. The other complex disease I work on are the allergic disease, where I am involved in both human and animal based studies of allergic dermatitis and asthma.The types of data to be analysed include genome-wide genotype data and ev ....This fellowship supports continuing work on statistical methods and applications for the detection and characterization of genes involved in complex diseases, notably melanoma, but a number of related characteristics such as skin hair and eye colour, moles and freckling. The other complex disease I work on are the allergic disease, where I am involved in both human and animal based studies of allergic dermatitis and asthma.The types of data to be analysed include genome-wide genotype data and eventually whole genome sequence data.Read moreRead less