Robust, valid and interpretable deep learning for quantitative imaging. One of the biggest challenges in employing artificial intelligence is the “black-box” nature of the models used. This project aims to improve the effectiveness and trustworthiness of deep learning within quantitative magnetic resonance imaging. Deep learning has great promise in speeding-up complex image processing tasks, but currently suffers from variable data inputs, predictions are not guaranteed to be plausible and it i ....Robust, valid and interpretable deep learning for quantitative imaging. One of the biggest challenges in employing artificial intelligence is the “black-box” nature of the models used. This project aims to improve the effectiveness and trustworthiness of deep learning within quantitative magnetic resonance imaging. Deep learning has great promise in speeding-up complex image processing tasks, but currently suffers from variable data inputs, predictions are not guaranteed to be plausible and it is not clear to the end user how reliable the results are. The outcomes intend to deliver advanced knowledge and capability in artificial intelligence and machine learning that Australia urgently needs to capitalise on bringing deep learning into practical applications delivering economic, commercial and social impact.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100972
Funder
Australian Research Council
Funding Amount
$382,462.00
Summary
Reaching deeper into neuronal networks using optical physics. Understanding the functions and intricacies of the brain is a fundamental challenge in scientific research. This project aims to develop new technologies to construct a microscope able to alter and make sense of neuronal activity in situ. This project also aims to investigate the precise role of a key brain region involved in sensory processing: the locus coeruleus. The results will reveal how this brain region influences brain dynami ....Reaching deeper into neuronal networks using optical physics. Understanding the functions and intricacies of the brain is a fundamental challenge in scientific research. This project aims to develop new technologies to construct a microscope able to alter and make sense of neuronal activity in situ. This project also aims to investigate the precise role of a key brain region involved in sensory processing: the locus coeruleus. The results will reveal how this brain region influences brain dynamics as well as behaviour. Expected outcomes include state of the art microscopes, high impact publications, and international collaborations. The anticipated benefits are the high quality training of the Australian workforce and further establishment of Australia as a leader in microscopy and neuroscience.Read moreRead less
Dielectric contrast imaging for 7 Tesla magnetic resonance applications. This project aims to develop novel radio-frequency (RF) technology, ensuring that the benefits of high-field magnetic resonance imaging (MRI) are available for a broader range of applications. This project will develop a new contrast mechanism directly related to the RF properties of individual tissue types, circumventing a limitation of intensity based imaging. This technology will enhance Australia’s global impact the dev ....Dielectric contrast imaging for 7 Tesla magnetic resonance applications. This project aims to develop novel radio-frequency (RF) technology, ensuring that the benefits of high-field magnetic resonance imaging (MRI) are available for a broader range of applications. This project will develop a new contrast mechanism directly related to the RF properties of individual tissue types, circumventing a limitation of intensity based imaging. This technology will enhance Australia’s global impact the development of imaging technology for healthcare, biomedical research and advanced diagnostics.Read moreRead less
Advanced Magnetic Resonance Imaging at 7 Tesla: Resolving the fundamental radiofrequency field-tissue interaction problem at ultra-high field. Ultra-high-field Magnetic Resonance Imaging (MRI) systems offer the potential for faster, more accurate diagnostic imaging. However, current applications are limited by the fundamental challenge of strong interactions between the electromagnetic field and human tissues, which result in poor image quality and/or compromised patient safety. Using a novel, s ....Advanced Magnetic Resonance Imaging at 7 Tesla: Resolving the fundamental radiofrequency field-tissue interaction problem at ultra-high field. Ultra-high-field Magnetic Resonance Imaging (MRI) systems offer the potential for faster, more accurate diagnostic imaging. However, current applications are limited by the fundamental challenge of strong interactions between the electromagnetic field and human tissues, which result in poor image quality and/or compromised patient safety. Using a novel, subject-specific imaging approach, this research will design and develop an ultra-high-field radiofrequency technology capable of offering high-performance imaging without jeopardising patient safety. This research will lay the groundwork for the translation of ultra-high field MRI research into clinical practice, generating new capabilities for diagnostic technologies.Read moreRead less
Developing a simple method for characterising the mechanical properties of nanowhiskers. This project aims to accurately measure mechanical properties of nanostructures, addressing a challenging issue in the ongoing development of nanotechnology. The success of this project will provide important advances in the understanding of the mechanical behaviour of nanowhiskers and assist in the further development of nanomaterials.
Discovery Early Career Researcher Award - Grant ID: DE210100205
Funder
Australian Research Council
Funding Amount
$367,000.00
Summary
Searching for Life on Mars on Earth. Australia continues to play a world-leading role in researching planetary habitability. This project will deliver the most comprehensive investigation of Earth’s oldest known river/lake deposits, uniquely preserved in 2.8 billion-year-old rocks in Western Australia. Using the candidate’s expertise in field investigation in combination with a cutting-edge analytical approach, the project will produce a detailed reconstruction of the ancient lake environment. S ....Searching for Life on Mars on Earth. Australia continues to play a world-leading role in researching planetary habitability. This project will deliver the most comprehensive investigation of Earth’s oldest known river/lake deposits, uniquely preserved in 2.8 billion-year-old rocks in Western Australia. Using the candidate’s expertise in field investigation in combination with a cutting-edge analytical approach, the project will produce a detailed reconstruction of the ancient lake environment. Similar settings will be explored by NASA's upcoming Mars 2020 rover mission at it's landing site in Jezero Crater. Mission data will be analysed by the candidate, who will guide the selection of samples and address the overarching question of whether microbal life ever existed on Mars.Read moreRead less
Developing innovative methodologies to understand nano-adhesion/friction. The project seeks to improve the measurement of nanoscale adhesion and friction. The understanding of adhesion and friction between a nanowhisker and a substrate is crucial for developing next-generation nanodevices. However, the current methods for measuring nanoscale adhesion and friction are inaccurate and can produce contradictory results, due to the extreme challenges in mastering sophisticated measuring techniques an ....Developing innovative methodologies to understand nano-adhesion/friction. The project seeks to improve the measurement of nanoscale adhesion and friction. The understanding of adhesion and friction between a nanowhisker and a substrate is crucial for developing next-generation nanodevices. However, the current methods for measuring nanoscale adhesion and friction are inaccurate and can produce contradictory results, due to the extreme challenges in mastering sophisticated measuring techniques and the lack of understanding of their underlying mechanisms. This project aims to develop innovative ‘push-peel’ and ‘push-slide’ methods to accurately measure those properties and to further understand their fundamental origins. Successful outcomes from this study would not only solve a long-standing problem in the application of nanowhiskers, but also generate new nanosurface science.Read moreRead less