Stochastic modelling of genetic regulatory networks with burst process. This project will develop the next generation of stochastic modelling to study the fundamental principles of genetic regulation. Simulations will yield deeper insight into the origin of bistability and oscillation in gene networks.
Discovery Early Career Researcher Award - Grant ID: DE240101190
Funder
Australian Research Council
Funding Amount
$451,000.00
Summary
Innovating and Validating Scalable Monte Carlo Methods. This project aims to develop innovative scalable Monte Carlo methods for statistical analysis in the presence of big data or complex mathematical models. Existing approaches to scalable Monte Carlo are only approximate, and their inaccuracies are difficult to quantify. This can have a detrimental impact on data-based decision making. The expected outcomes of this project are scalable Monte Carlo methods that are more accurate, fast and capa ....Innovating and Validating Scalable Monte Carlo Methods. This project aims to develop innovative scalable Monte Carlo methods for statistical analysis in the presence of big data or complex mathematical models. Existing approaches to scalable Monte Carlo are only approximate, and their inaccuracies are difficult to quantify. This can have a detrimental impact on data-based decision making. The expected outcomes of this project are scalable Monte Carlo methods that are more accurate, fast and capable of quantifying inaccuracies. Scientists and decision-makers will benefit from the ability to obtain timely, reliable insights for challenging applications.Read moreRead less
Improved Monte Carlo Methods for Estimation, Optimisation and Counting. The project will benefit the Australian society by building the theoretical and methodological foundations for the next generation of Monte Carlo techniques. The advancement of the knowledge in this area will provide important tools for solving complex estimation, optimisation and counting problems in engineering, statistics, computer science, mathematics and the physical and life sciences. As a result it will generate a com ....Improved Monte Carlo Methods for Estimation, Optimisation and Counting. The project will benefit the Australian society by building the theoretical and methodological foundations for the next generation of Monte Carlo techniques. The advancement of the knowledge in this area will provide important tools for solving complex estimation, optimisation and counting problems in engineering, statistics, computer science, mathematics and the physical and life sciences. As a result it will generate a competitive advantage for various sections of the Australian industry, including telecommunications, biotechnology and finance. The project will enable Australian researchers to continue to work at the forefront of this fast moving and exciting area of international research.Read moreRead less
Stochastic modelling of spatiotemporal nonlinear diffusion processes with multifractal characteristics. This research is relevant to solute transport and plume evolution in heterogeneous media. Detailed modelling of these processes is computer-intensive, while the diffusion models of this project offer a more economical alternative. Our study will also benefit the research on the salinity problem. Excessive demand for irrigation water to support agricultural production has stretched freshwater a ....Stochastic modelling of spatiotemporal nonlinear diffusion processes with multifractal characteristics. This research is relevant to solute transport and plume evolution in heterogeneous media. Detailed modelling of these processes is computer-intensive, while the diffusion models of this project offer a more economical alternative. Our study will also benefit the research on the salinity problem. Excessive demand for irrigation water to support agricultural production has stretched freshwater aquifers beyond their long-term yield. Large areas of land have been lost to saltwater intrusion. This proposal will provide suitable tools to predict the level and movement of saltwater in the aquifers. Application to the development of management strategies would bring direct benefit to coastal areas where salinity is a sustainability issue.Read moreRead less
Stochastic modelling and analysis of spatio-temporal processes with fractal characteristics. Interest has grown in recent years on the derivation of fractal models to represent certain physical phenomena such as diffusion and transport in porous media, oceanic and atmospheric turbulence, climatology, etc. This project focuses on the phenomenon of diffusion on domains with multifractal geometry. Recent advances in harmonic analysis on fractals and our own development of fractional generalized ran ....Stochastic modelling and analysis of spatio-temporal processes with fractal characteristics. Interest has grown in recent years on the derivation of fractal models to represent certain physical phenomena such as diffusion and transport in porous media, oceanic and atmospheric turbulence, climatology, etc. This project focuses on the phenomenon of diffusion on domains with multifractal geometry. Recent advances in harmonic analysis on fractals and our own development of fractional generalized random fields allow us to formulate a comprehensive program to tackle some key problems including modeling, processing and statistical estimation of fractional diffusion. Advances made in this program will in turn benefit the developments in related scientific fields.Read moreRead less
Increasing the effectiveness of quantitative verification. The ability to analyse the performance of complex systems and protocols is a vital part of the development of large-scale computer applications. Methods that improve the effectiveness of the analysis task would increase the competitiveness of the software industry, and would attract future development work (in complex systems) to Australia. The results of this project will have a direct influence on currently available design tools; the ....Increasing the effectiveness of quantitative verification. The ability to analyse the performance of complex systems and protocols is a vital part of the development of large-scale computer applications. Methods that improve the effectiveness of the analysis task would increase the competitiveness of the software industry, and would attract future development work (in complex systems) to Australia. The results of this project will have a direct influence on currently available design tools; the fact that Australian institutions will be (in part) responsible for key theoretical results in this growing field will strengthen Australia's position worldwide as an international centre for computer science.Read moreRead less
Inference for Hawkes processes with challenging data. The Hawkes processes are statistical models for the analysis of high-impact event sequences, such as bushfires, earthquakes, infectious diseases, and cyber attacks. When the times and/or marks are missing for some events or when the data is otherwise incomplete, it is challenging to fit these models and perform diagnostic checks on the fitted models. This project aims to develop novel statistical methods to fit these models in the presence of ....Inference for Hawkes processes with challenging data. The Hawkes processes are statistical models for the analysis of high-impact event sequences, such as bushfires, earthquakes, infectious diseases, and cyber attacks. When the times and/or marks are missing for some events or when the data is otherwise incomplete, it is challenging to fit these models and perform diagnostic checks on the fitted models. This project aims to develop novel statistical methods to fit these models in the presence of incomplete data and to check the goodness-of-fit of the fitted models. The expected outcomes include publications documenting these methods and software packages implementing them. The primary benefits include the advancement of statistical methodology and the training of junior research personnel. Read moreRead less
Operator-Analytic Methods in Telecommunication Systems. Many systems in information technology and telecommunications evolve under conditions of uncertainty. In this context, mathematical modelling is an essential component of the design process. We shall provide techniques for analysing a class of mathematical models, called operator-analytic models, which can be used to study many of the above-mentioned systems, such as the Internet. This project will deliver efficient numerical algorithms tha ....Operator-Analytic Methods in Telecommunication Systems. Many systems in information technology and telecommunications evolve under conditions of uncertainty. In this context, mathematical modelling is an essential component of the design process. We shall provide techniques for analysing a class of mathematical models, called operator-analytic models, which can be used to study many of the above-mentioned systems, such as the Internet. This project will deliver efficient numerical algorithms that will make possible practical analysis of operator-analytic models.Read moreRead less
Bayesian Inference for Multivariate Hierarchical Regression Models. This project will develop Bayesian methodology for analysing multivariate regression models. The distribution of each measurement can be discrete or continuous, with the dependence between measurements obtained through the correlation matrix of a Gaussian copula. Model parsimony is obtained by identifying zero elements in the correlation matrix or its inverse and by variable selection on the regression parameters. The results wi ....Bayesian Inference for Multivariate Hierarchical Regression Models. This project will develop Bayesian methodology for analysing multivariate regression models. The distribution of each measurement can be discrete or continuous, with the dependence between measurements obtained through the correlation matrix of a Gaussian copula. Model parsimony is obtained by identifying zero elements in the correlation matrix or its inverse and by variable selection on the regression parameters. The results will be applied to solve problems in finance, health management and marketing. In all these fields multiple observations are often taken per individual or time period and the models need to incorporate measures of dependence and uncertainty.Read moreRead less
Mechanism design for next generation random access wireless protocols. Australia is well placed to take the lead in replacing carbon-intensive travel by teleconferencing, because of its isolation and geographic dispersion. Because these large distances introduce inevitable delays, it is important that the network itself add as little delay as possible for such real-time services. Our novel and practical resource allocation scheme will enable Australians (including Australian industries and rural ....Mechanism design for next generation random access wireless protocols. Australia is well placed to take the lead in replacing carbon-intensive travel by teleconferencing, because of its isolation and geographic dispersion. Because these large distances introduce inevitable delays, it is important that the network itself add as little delay as possible for such real-time services. Our novel and practical resource allocation scheme will enable Australians (including Australian industries and rural communities) to receive better service at lower cost. This project will put Australia on the international stage as a leading contributor to wireless Internet technology. We will provide training for PhD students and postdoctoral fellows in this important area.Read moreRead less