New Theory and Algorithms for Nonsmooth Optimisation with Application to Integer Programming. Mathematical optimisation plays a key role in a wide variety of applications in business, industry, engineering and science. For example, airlines cannot fly and radiation treatment for cancer cannot be delivered without solving (a series of) optimisation problems. Some classes of optimisation problem are very well solved, with clear mathematical foundations, efficient algorithms, and reliable software ....New Theory and Algorithms for Nonsmooth Optimisation with Application to Integer Programming. Mathematical optimisation plays a key role in a wide variety of applications in business, industry, engineering and science. For example, airlines cannot fly and radiation treatment for cancer cannot be delivered without solving (a series of) optimisation problems. Some classes of optimisation problem are very well solved, with clear mathematical foundations, efficient algorithms, and reliable software implementations. Both nonsmooth and integer optimisation problems have a good mathematical basis, but there are "gaps"; existing methods cannot always solve real industrial problems. This project will deliver better methods, built on better theory, and so will yield better solutions for important applications.Read moreRead less
Response of Proteins to External Non-Ionising Radiation: an Experimental and Computer Modelling Investigation. The expanding use of digital technologies such as mobile phones has led to major health concerns about the effects of non-ionising pulsed radiation exposure which has been shown to produce instantaneous temperature rises undetectable by normal thermometry. The health implications of exposure are not understandable without establishing molecular mechanisms by which pulsed microwaves can ....Response of Proteins to External Non-Ionising Radiation: an Experimental and Computer Modelling Investigation. The expanding use of digital technologies such as mobile phones has led to major health concerns about the effects of non-ionising pulsed radiation exposure which has been shown to produce instantaneous temperature rises undetectable by normal thermometry. The health implications of exposure are not understandable without establishing molecular mechanisms by which pulsed microwaves can cause biological effects. We aim to establish methods for studying the molecular mechanisms of protein structural and energetic changes occurring due to non-ionising radiation. The results will help our industry partner to design specific drugs as well as formulate a scientifically based standard for microwave utilisation.Read moreRead less
Improving train flows with connected driver advice systems. The project aims to develop new train control theory to determine the efficient movement of multiple trains, and to demonstrate a practical system for coordinating trains, on busy intercity rail corridors. Railways around the world are now deploying driver advice systems developed by the research team and the partner organisation, TTG Transportation Technology. The project is designed to enable these systems to coordinate the movements ....Improving train flows with connected driver advice systems. The project aims to develop new train control theory to determine the efficient movement of multiple trains, and to demonstrate a practical system for coordinating trains, on busy intercity rail corridors. Railways around the world are now deploying driver advice systems developed by the research team and the partner organisation, TTG Transportation Technology. The project is designed to enable these systems to coordinate the movements of many trains on a congested rail network to improve timekeeping, smooth the flow of traffic, increase capacity and reduce energy use.Read moreRead less
Structured barrier and penalty functions in infinite dimensional optimisation and analysis. Very large scale tightly-constrained optimisation problems are ubiquitous and include water management, traffic flow, and imaging at telescopes and hospitals. Massively parallel computers can solve such problems and provide physically realisable solution only if subtle design issues are mastered. Resolving such issues is the goal of this project.
Industrial Transformation Research Hubs - Grant ID: IH130200012
Funder
Australian Research Council
Funding Amount
$2,748,358.00
Summary
ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, ....ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). ARC Research Hub for Basin GEodyNamics and Evolution of SedImentary Systems (GENESIS). This Research Hub aims to undertake simultaneous modelling of deep Earth and surface processes, spanning basin scales to individual sediment grains. The Hub will develop and apply cutting-edge basin simulation approaches to transform the seeding and testing of basin exploration models, extending their viability to complex, inaccessible remote and deep exploration targets. The Hub will fuse multidimensional data into five dimensional basin models (space and time, with uncertainty estimates) by coupling the evolution of mantle flow, crustal deformation, erosion and sedimentary processes, achieving a quantum leap in basin modelling and petroleum systems analysis.Read moreRead less
Risk Measures and Management in Finance and Actuarial Science Under Regime-Switching Models. New models for assessing and managing risk of financial products will place Australia at the forefront of risk management. The work will also sustain the competitive edge of Australia as one of the major financial centres in the Asia-Pacific region through enhancing both the theory and practice of financial risk management. The project outcome will also benefit to the country in other areas of risk, for ....Risk Measures and Management in Finance and Actuarial Science Under Regime-Switching Models. New models for assessing and managing risk of financial products will place Australia at the forefront of risk management. The work will also sustain the competitive edge of Australia as one of the major financial centres in the Asia-Pacific region through enhancing both the theory and practice of financial risk management. The project outcome will also benefit to the country in other areas of risk, for example, environment risk, climate change, and energy and security problems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100051
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Maintaining and enhancing merit-based access to the NCI National Facility. Maintaining and enhancing merit-based access to the national computational infrastructure facility:
This project aims to ensure that Australian researchers have access to the integrated high-performance computing and data environments they need. Australia’s national computational infrastructure (NCI) is the national, high-end research computing facility, providing researchers in universities, government science agencies ....Maintaining and enhancing merit-based access to the NCI National Facility. Maintaining and enhancing merit-based access to the national computational infrastructure facility:
This project aims to ensure that Australian researchers have access to the integrated high-performance computing and data environments they need. Australia’s national computational infrastructure (NCI) is the national, high-end research computing facility, providing researchers in universities, government science agencies and industry with world-class, integrated, high-performance services. These services enable high-impact, data-intensive computational research in all fields of science and technology. This project would continue merit-based access to NCI at the current level, ensuring ongoing international competitiveness of Australian research.Read moreRead less
An In Depth Analysis Of Clinical And Virological Outcomes Of 2 Strategies For The Antiretroviral Salvage Of First-line Regimen Virological Failure For HIV-1 Infection Tested In An Australian-led Randomised, International, Multi-centre Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
The recently completed Australian-led SECOND-LINE trial is the first high quality study to provide reliable evidence for policy recommendations for the composition of anti-HIV drug cocktails after standard initial treatment has failed. This award will support the researcher in further refining our understanding of how to manage second-line therapy including proposals to test the use of low-cost technologies for application in resource-limited settings where the majority of people with HIV live.
An integrated modelling approach for efficient management of irrigated landscapes. Northern Victoria's irrigators use a substantial portion of water from the Murray-Darling Basin, which is under mounting pressure to satisfy competing economic, social and environmental needs for water in the face of climate change. Up to 20 per cent of this water may be on-farm surface runoff and deep percolation, with poorly known spatial distributions. This project will provide reliable temporally and spatially ....An integrated modelling approach for efficient management of irrigated landscapes. Northern Victoria's irrigators use a substantial portion of water from the Murray-Darling Basin, which is under mounting pressure to satisfy competing economic, social and environmental needs for water in the face of climate change. Up to 20 per cent of this water may be on-farm surface runoff and deep percolation, with poorly known spatial distributions. This project will provide reliable temporally and spatially distributed information on surface runoff and deep percolation for Northern Victoria irrigation regions. This will inform decisions which improve water use efficiency, agricultural productivity and environmental values through optimisation of irrigation infrastructure and by better management of groundwater resources and salinity.Read moreRead less
Design of Tough, Durable and Corrosion-resistant Coatings. Coatings are frequently applied to components operating in harsh environments to enhance durability. Often such coatings exhibit low toughness and poor corrosion resistance that leads to premature failure. The aim of this project is to design, characterise and test innovative coatings that exhibit unique architectures based on natural materials such as teeth and nacre. It is envisaged that these coatings will be hard, tough and durable i ....Design of Tough, Durable and Corrosion-resistant Coatings. Coatings are frequently applied to components operating in harsh environments to enhance durability. Often such coatings exhibit low toughness and poor corrosion resistance that leads to premature failure. The aim of this project is to design, characterise and test innovative coatings that exhibit unique architectures based on natural materials such as teeth and nacre. It is envisaged that these coatings will be hard, tough and durable in hostile, corrosive environments, and will thus, transform industries such as manufacturing, mining and offshore oil exploration as well as enhance the lifetime of prosthetic devices.Read moreRead less