Derivative free algorithms for large scale nonsmooth and global optimization and their applications. The outcomes expected from this research fall broadly into two categories: 1) the development of a new class of effective readily implementable derivative free techniques for large scale non-smooth and global optimisation and 2) the development of new algorithms based on derivative free optimization techniques for solving data mining, resource allocation problems and some problems in bioinformati ....Derivative free algorithms for large scale nonsmooth and global optimization and their applications. The outcomes expected from this research fall broadly into two categories: 1) the development of a new class of effective readily implementable derivative free techniques for large scale non-smooth and global optimisation and 2) the development of new algorithms based on derivative free optimization techniques for solving data mining, resource allocation problems and some problems in bioinformatics. In particular, the application of these techniques to molecular biology and cluster analysis will be very important for the development of competitive technologies for Australia.
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Approximate bundle methods in nonsmooth optimisation and their applications in some complex systems. Non-smooth and non-convex optimisation has many applications in industry and science. One of the powerful methods in non-smooth optimisation is a bundle method. This project will develop new versions of the bundle method by using continuous approximations to the sub-differential and extend this method for solving non-convex (smooth and non-smooth) optimisation problems by using max-min of linear ....Approximate bundle methods in nonsmooth optimisation and their applications in some complex systems. Non-smooth and non-convex optimisation has many applications in industry and science. One of the powerful methods in non-smooth optimisation is a bundle method. This project will develop new versions of the bundle method by using continuous approximations to the sub-differential and extend this method for solving non-convex (smooth and non-smooth) optimisation problems by using max-min of linear functions for the approximation of the functions involved. The outcome will be a new class of effective readily implementable algorithms for the minimization of non-smooth and non-convex functions, whose usefulness will be demonstrated by applications in cluster analysis, biochemistry and robotics.
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Filled function methods for global optimization and their applications. Many real problems in science, commerce and industry are restricted in the way that they are modelled and solved by the known inability to deal with global optimization problems. The development of computational efficient global optimization methods in this project will allow new more complete approaches to these problems, especially in new areas of bio-informatics, data mining, economic modelling, supply chain management, ....Filled function methods for global optimization and their applications. Many real problems in science, commerce and industry are restricted in the way that they are modelled and solved by the known inability to deal with global optimization problems. The development of computational efficient global optimization methods in this project will allow new more complete approaches to these problems, especially in new areas of bio-informatics, data mining, economic modelling, supply chain management, air traffic management, biochemical engineering and automotive industry, consequently helping Australia advance in these various areas. It will also enhance the understanding of global optimization from both theoretical and numerical viewpoints, particularly boosting optimization research in Australia.Read moreRead less
Information Geometry and Compressive Sensing for Radar and Communications. Australia's vast distances, thin population and extensive sea approaches force us to place heavy reliance on telecommunications and the remote sensing that radar and other modalities can provide. This project will enchance capabilities in sensing to provide more reliable, robust and cost effective communications and surveillance over a wide area.
GEOMETRIC NUMERICAL INTEGRATION. Many scientific phenomena in physics, astronomy, and chemistry, are modelled by ordinary differential equations (ODEs). Often these equations have no solution in closed form, and one relies on numerical integration. Traditionally this is done using Runge-Kutta methods or linear multistep methods. In the last decade, however, we (and others) have discovered novel classes of so-called "geometric" numerical integration methods that preserve qualititative featur ....GEOMETRIC NUMERICAL INTEGRATION. Many scientific phenomena in physics, astronomy, and chemistry, are modelled by ordinary differential equations (ODEs). Often these equations have no solution in closed form, and one relies on numerical integration. Traditionally this is done using Runge-Kutta methods or linear multistep methods. In the last decade, however, we (and others) have discovered novel classes of so-called "geometric" numerical integration methods that preserve qualititative features of certain ODE's exactly (in contrast to traditional methods), leading to crucial stability improvements. Extending concepts from dynamical systems theory and traditional numerical ODEs, this project will improve, extend and systematize this new field of geometric integration.Read moreRead less
Geometric Integration. This project gives an important boost to Australia's strength in the niche area of geometric numerical integration,in the face of strong international competition. It gathers 7 world experts from 5 countries to create new computer programs to improve calculations in dynamics, with applications ranging from astronomy, physics, chemistry, biology, and meteorology to finance. It strengthens Australia's links with the mathematical software industry, and will lead to world-clas ....Geometric Integration. This project gives an important boost to Australia's strength in the niche area of geometric numerical integration,in the face of strong international competition. It gathers 7 world experts from 5 countries to create new computer programs to improve calculations in dynamics, with applications ranging from astronomy, physics, chemistry, biology, and meteorology to finance. It strengthens Australia's links with the mathematical software industry, and will lead to world-class graduates and research training.Read moreRead less
Geometric numerical integration of differential equations. Differential equations (DEs) play a central role in modelling scientific phenomena in physics, biology, chemistry, astronomy, meteorology, and geoscience. We have developed new ways of solving DEs, using geometric integration, which have significant advantages over traditional methods because of the crucial nonlinear stability they provide.
This project, combining 7 world experts from 6 countries and 1 early career researcher, will pl ....Geometric numerical integration of differential equations. Differential equations (DEs) play a central role in modelling scientific phenomena in physics, biology, chemistry, astronomy, meteorology, and geoscience. We have developed new ways of solving DEs, using geometric integration, which have significant advantages over traditional methods because of the crucial nonlinear stability they provide.
This project, combining 7 world experts from 6 countries and 1 early career researcher, will place Australia at the forefront of this intensive international activity.
It will significantly strengthen Australia's links with the mathematical software industry (e.g. Wolfram Research, Inc), and will lead to world class graduates and research training.
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Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV? Approximately 15,000 individuals in Australia are currently HIV infected. Gene therapy has the capacity to remove antiretroviral treatment related issues, dramatically decrease treatment costs and simplify treatment of HIV.
In this study we will model a new approach to treat HIV in which the patient's own cells are used as the therapy by incorporating an anti-HIV gene. These cells are then re-introduced into the p ....Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV? Approximately 15,000 individuals in Australia are currently HIV infected. Gene therapy has the capacity to remove antiretroviral treatment related issues, dramatically decrease treatment costs and simplify treatment of HIV.
In this study we will model a new approach to treat HIV in which the patient's own cells are used as the therapy by incorporating an anti-HIV gene. These cells are then re-introduced into the patient.
The strong mathematical focus of this project, and its application to a promising approach against HIV, will place Australia at the forefront of the mathematics of gene research and contribute to the National Priority Area of Promoting and Maintaining Good Health and the Priority Goal of Preventative Healthcare.
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Integrating dynamic and optimization models for efficient pipeline system operations in an evolving water and energy market. Developing an integrated dynamical and optimisation model for a piped water distribution system will advance Australia's capacity to deploy the most recent optimisation approaches to achieve the high level of efficiency required in the delivery of water to dryland regions. The outcomes of this project will be readily transferable to other regions and indeed other water d ....Integrating dynamic and optimization models for efficient pipeline system operations in an evolving water and energy market. Developing an integrated dynamical and optimisation model for a piped water distribution system will advance Australia's capacity to deploy the most recent optimisation approaches to achieve the high level of efficiency required in the delivery of water to dryland regions. The outcomes of this project will be readily transferable to other regions and indeed other water distribution systems. This will provide capability in securing Australia's water supplies and delivery systems. There may also be associated benefits to other pipeline operators in the oil and gas industries.Read moreRead less
Construction of utility functions from observations of consumer behaviour with application to resource modelling and water management strategies. The optimisation techniques developed will be on the forefront of applied mathematical sciences and will increase the prestige of the Australian mathematical community. The expected results will also be of value because they can be used to improve the CGE modelling technique. The implementation of the CGE model of one of Victoria's agricultural regions ....Construction of utility functions from observations of consumer behaviour with application to resource modelling and water management strategies. The optimisation techniques developed will be on the forefront of applied mathematical sciences and will increase the prestige of the Australian mathematical community. The expected results will also be of value because they can be used to improve the CGE modelling technique. The implementation of the CGE model of one of Victoria's agricultural regions will be used to improve the accuracy of regional economic models and will contribute to efficient regional resource management. This has the potential to positively affect the economic growth and employment in the region. The expected outcomes of the project are especially important taking into account the need for predicting the socio-economic consequences of the 1994 COAG water reforms. Read moreRead less