Developing innovative concrete composites by upscaling material properties. This project aims to develop an upscaling process to correlate micro-nano properties of engineering materials to their comprehensive physicochemical properties based on systematic mechanical and statistical analysis approaches and nanoindentation technology. The process will enable assessing material mechanical and viscoelastic properties at a microscale level thus will generate a new knowledge in structural engineering ....Developing innovative concrete composites by upscaling material properties. This project aims to develop an upscaling process to correlate micro-nano properties of engineering materials to their comprehensive physicochemical properties based on systematic mechanical and statistical analysis approaches and nanoindentation technology. The process will enable assessing material mechanical and viscoelastic properties at a microscale level thus will generate a new knowledge in structural engineering discipline including health monitoring, assessment of existing structures, historical buildings, and strengthening and repairing materials in structures. The outcomes are a multiscale link model for upscaling material properties and a development of innovative reinforced concrete composites which are cost-effective and efficient.Read moreRead less
Ethics and aesthetics as criteria for innovation: A design research study of biological art and digital architecture. The project will contribute to the goal of promoting innovation in three areas. First, the project will amplify Australia's individual strengths in biological art and digital architecture by creating a network of artists and designers in which each discipline is stimulated by the concerns and practices of the other. Second, the project will explain innovation in such networks, by ....Ethics and aesthetics as criteria for innovation: A design research study of biological art and digital architecture. The project will contribute to the goal of promoting innovation in three areas. First, the project will amplify Australia's individual strengths in biological art and digital architecture by creating a network of artists and designers in which each discipline is stimulated by the concerns and practices of the other. Second, the project will explain innovation in such networks, by identifying activities that lead to innovation. Such an explanation will improve the nation's capacity to promote innovation in targeted fields. Third, the project will test and develop collaboration tools designed to support the activities identified as leading to innovation, as information technology is a primary enabler for operating across such networks.
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Design practice research: uncovering the role of spatial intelligence in designing and in reviewing design of the built environment. This project will result in the identification and methodical analysis of spatial intelligence as deployed by Architects, Landscape Architects and Urban Designer practitioners. It will also explore improvements and invention of new design policies and design procurement procedures which are informed by deeper understandings of Spatial Intelligence.
Braced batter micropile group: New design theory and performance framework. Braced batter micropile group: New design theory and performance framework. This project aims to research the design and performance of innovative biomimetic braced battered micropile group footings. This project will test Surefoot, the new concrete free footing, in the laboratory, in the field, and through numerical and analytical modelling. Surefoot’s mechanisms of action are poorly understood but clearly more complex ....Braced batter micropile group: New design theory and performance framework. Braced batter micropile group: New design theory and performance framework. This project aims to research the design and performance of innovative biomimetic braced battered micropile group footings. This project will test Surefoot, the new concrete free footing, in the laboratory, in the field, and through numerical and analytical modelling. Surefoot’s mechanisms of action are poorly understood but clearly more complex than current micropile theory; this project will research the mechanism of load transfer from micropiles to the soil and soil response.Read moreRead less
The Australian Centre of Excellence in Twin Research will build on the Australian Twin Registry, which for 30 years has played an integral part in health & medical research. The new Centre aims to expand a state-of-the-art resource for conducting research, bring together leading national and international researchers from across disciplines, and build capacity in people, techniques, and expertise to continue to enable twin research to address major health and medical issues.
Centre Of Research Excellence On Sitting Time And Chronic Disease Prevention – Mechanisms, Measurement And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$2,657,874.00
Summary
Australian research has identified serious health consequences arising from the 7 to 10 hours of daily sitting that most people do, especially in relation to ‘diseases of inactivity’ – type 2 diabetes, coronary heart disease and breast and colon cancer – that are an unwelcome burden on individuals, families and health systems. This new research examines the practical feasibility and the preventive-health benefits of changing children’s and adults’ sitting time in schools, workplaces and the home ....Australian research has identified serious health consequences arising from the 7 to 10 hours of daily sitting that most people do, especially in relation to ‘diseases of inactivity’ – type 2 diabetes, coronary heart disease and breast and colon cancer – that are an unwelcome burden on individuals, families and health systems. This new research examines the practical feasibility and the preventive-health benefits of changing children’s and adults’ sitting time in schools, workplaces and the home environment.Read moreRead less
Towards A National Sports Safety Strategy - Addressing Facilitators And Barriers Towards Safety Guideline Uptake.
Funder
National Health and Medical Research Council
Funding Amount
$965,834.00
Summary
Most sports injury prevention evidence is yet to be translated from professional to community sports settings. Using community-based Australian football clubs, this project will develop and evaluate the strategic implementation of an evidence-based sports safety package. This will provide important information about how to best support community sports clubs to ensure evidence-based safety programs are translated into sustainable policies and practice and public health benefits are maximised
A Structural Investigation Into The T-cell Response To Epstein Barr Virus Infection
Funder
National Health and Medical Research Council
Funding Amount
$549,000.00
Summary
X-ray crystallography is an essential tool for solving the three-dimensional structure of proteins. Proteins control the biological processes within the cell and it is the precise shape of proteins that determines how they function. Depending on the particular sequence of the amino acids, the so-called building unit of the proteins, the protein molecule bends and forms a distinct, complex shape. This specific three-dimensional shape allows the protein to undertake its specific function, such as ....X-ray crystallography is an essential tool for solving the three-dimensional structure of proteins. Proteins control the biological processes within the cell and it is the precise shape of proteins that determines how they function. Depending on the particular sequence of the amino acids, the so-called building unit of the proteins, the protein molecule bends and forms a distinct, complex shape. This specific three-dimensional shape allows the protein to undertake its specific function, such as binding to other proteins, acting as an enzyme or interacting with nucleic acids. To determine how a protein acts, it is vital to know the precise three-dimensional shape at the atomic level. This proposal is concerned with understanding the precise shape of proteins that control the immune response to Epstein Barr Virus. Epstein Barr Virus is an ubiquitous human pathogen that has being linked to a number of cancers. This work will further our understanding of the immune response to Epstein Barr Virus.Read moreRead less
Genome-wide Association Study (GWAS) For Juvenile-onset Myopia And Its Component Measures To Identify Molecular Pathways To Prevent Myopia
Funder
National Health and Medical Research Council
Funding Amount
$495,364.00
Summary
We will examine 2,000 young adults from the Western Australian Raine Cohort at the Lions Eye Institute / University of Western Australia. Ocular data will be collected relating to myopia (short-sightedness) and will be combined with extensive previous childhood and genetic research data collected on the Cohort, to investigate the genetic and environmental factors predisposing to myopia. This will assist in understanding the factors leading to myopia.
A Genome-wide Association Study In 2000 Glaucoma Cases With Matched Controls Using Equimoloar DNA Pools
Funder
National Health and Medical Research Council
Funding Amount
$610,267.00
Summary
Glaucoma is a common cause of loss of vision worldwide but we are unable to predict which people are at high risk of blindness. We aim to discover the genetic risk factors for glaucoma. We will use cutting edge genetic technology to assess the whole genome in thousands of patients with glaucoma. We hope to identify important new glaucoma genes, which could lead to the development of diagnostic tests and treatments which will provide the most cost-efficient ways to prevent glaucoma blindness.