I am a clinical researcher determining: a) the role of altered airway structure, particularly airway smooth muscle and extracellular matrix, in asthma and COPD; and b) the prevalence of, and risk factors for, respiratory disease in general populations.
The Integration Of High Level Clinical Medicine, Molecular Genics, And Cutting Edge Neuroimaging
Funder
National Health and Medical Research Council
Funding Amount
$4,000,000.00
Summary
I aim to cement my place as the leading clinical and translational researcher in epilepsy internationally. My research and that of my wider group is focused on the integration of high level clinical medicine, molecular genetics and cutting-edge neuroimaging, which is informed and enhanced by clinically relevant basic neuroscience. This integrative model is unique in the epilepsy field. The Fellowship will give me the opportunity to expand this model and optimally utilize the rapidly developing t ....I aim to cement my place as the leading clinical and translational researcher in epilepsy internationally. My research and that of my wider group is focused on the integration of high level clinical medicine, molecular genetics and cutting-edge neuroimaging, which is informed and enhanced by clinically relevant basic neuroscience. This integrative model is unique in the epilepsy field. The Fellowship will give me the opportunity to expand this model and optimally utilize the rapidly developing technologies in genetics and imaging which are the two most important and productive fields in clinical neuroscience. I am in a unique international position to do this because of the clinical cohorts that I have meticulously collected and characterized over the last two decades, working with the remarkable group of clinical and basic science investigators that form my personal research team, and the wider group that I head, supported by an NHMRC Program Grant. This Fellowship will provide for a major injection of additional core genetic expertise to take us up to the next level necessary to crack the challenging problem of the complex genetics of the epilepsies. I wish to increase the impact and reputation of my wider group as the International Centre for innovative and clinically relevant research in epilepsy. This will enhance the reputation of Australia as a place of excellence in health and medical research.Read moreRead less
I have established and head the Melbourne Neuropsychiatry Centre within the University of Melbourne. My university position is a research chair with the specific aim of leading a team of researchers in neuropsychiatric research. One of the goals of the Centre is to deliver world-class neuroimaging research in psychiatric disorders. I head a team of researchers that have been undertaking neuroimaging and neuropsychological work on schizophrenia and psychosis since 1993 in Australia. My particular ....I have established and head the Melbourne Neuropsychiatry Centre within the University of Melbourne. My university position is a research chair with the specific aim of leading a team of researchers in neuropsychiatric research. One of the goals of the Centre is to deliver world-class neuroimaging research in psychiatric disorders. I head a team of researchers that have been undertaking neuroimaging and neuropsychological work on schizophrenia and psychosis since 1993 in Australia. My particular interest and impact on the field has been to define and understand progressive brain changes in schizophrenia and related psychotic disorders. Further work will place these changes within a brain maturational context, particularly examining trajectories of development in adolescence and young adulthood.Read moreRead less
I am a clinican-scientist and rheumatologist studying genetic determinants of common chronic human musculoskeletal diseases. My research aims are to define for key genes how specific genotypes promote diease phenotypes, using in vitro and in vivo approac
I am working at the interface of quantitative, statistical, population and human genetics and bioinformatics, aiming to understand and unravel genetic variation in disease susceptibility and endophenotypes in human populations.
The applicant is a clinical psychologist. Research focuses on developing, evaluating and disseminating psychological interventions for co-existing mental health (e.g. schizophrenia, depression, anxiety) and alcohol and other drug problems (e.g. alcohol, c