Dhenia: A study of regionalism, population and society in Bronze Age Cyprus. The cemetery complex at Dhenia in Cyprus was in use for 2500 years, from the beginning of the Bronze Age (2,400 BCE) to the end of the Iron Age. This project is designed to sample this extensive site to assess its changing size and structure during periods of major social transformation. Comparative studies of contemporary sites will provide the basis for monitoring and explaining local, regional and island-wide relatio ....Dhenia: A study of regionalism, population and society in Bronze Age Cyprus. The cemetery complex at Dhenia in Cyprus was in use for 2500 years, from the beginning of the Bronze Age (2,400 BCE) to the end of the Iron Age. This project is designed to sample this extensive site to assess its changing size and structure during periods of major social transformation. Comparative studies of contemporary sites will provide the basis for monitoring and explaining local, regional and island-wide relationships, viewed in a context of expanding population and increasing interaction with the wider Mediterranean world. New data and approaches will contribute significantly to Cypriot archaeology and to broader archaeological theory.Read moreRead less
The impact of cultural contact between China and the Ancient Mediterranean World. The project which is part of a large international project aims to investigate the evidence for cultural contact between Rome and China and draws on material which has not been properly studied. Some of this material is of great artistic value (esp. Manichaean manuscripts) and has already attracted the attention of national media (newspapers, radio and TV). The project will help strengthen research ties between th ....The impact of cultural contact between China and the Ancient Mediterranean World. The project which is part of a large international project aims to investigate the evidence for cultural contact between Rome and China and draws on material which has not been properly studied. Some of this material is of great artistic value (esp. Manichaean manuscripts) and has already attracted the attention of national media (newspapers, radio and TV). The project will help strengthen research ties between the Social Science Academy of China and the Australian Academy of the Humanities. It will also heighten academic interest among ethnic groups: Chinese, Assyrian, Turkish and Iranian in cross-cultural contacts through exhibitions. Read moreRead less
China and the ancient Mediterranean world. The project which is part of a large international project aims to investigate the evidence for cultural contact between Rome and China and draws on material which has not been properly studied. Some of this material is of great artistic value (esp. Manichaean illuminated manuscripts) and has already attracted the attention of national media (newspapers, radio and TV). The project will also help strengthen research ties between the Social Science Academ ....China and the ancient Mediterranean world. The project which is part of a large international project aims to investigate the evidence for cultural contact between Rome and China and draws on material which has not been properly studied. Some of this material is of great artistic value (esp. Manichaean illuminated manuscripts) and has already attracted the attention of national media (newspapers, radio and TV). The project will also help strengthen research ties between the Social Science Academy of China and the Australian Academy of the Humanities. It will also heighten academic interest among ethnic groups: Chinese, Assyrian, Turkish and Iranian in cross-cultural contacts.Read moreRead less
Mission and Inculturation: the Manichaean and Nestorian experience in China - a textual, iconographical and epigraphical investigation. The project aims to investigate the introduction of two 'Western' religions, Manichaeism and Nestorian Christianity, into China through textual and archaeological evidence. The project will explore important multi-cultural aspects such as theological inculturation and artistic synthesis. The iconographical material from South China is both unique and of great ar ....Mission and Inculturation: the Manichaean and Nestorian experience in China - a textual, iconographical and epigraphical investigation. The project aims to investigate the introduction of two 'Western' religions, Manichaeism and Nestorian Christianity, into China through textual and archaeological evidence. The project will explore important multi-cultural aspects such as theological inculturation and artistic synthesis. The iconographical material from South China is both unique and of great artistic value and has already attracted the attention of national media (newspapers, radio and TV).Read moreRead less
Manichaean and Medieval Christian (Nestorian and Catholic) remains in Quanzhou (S. China) - an epigraphical, iconographical and historical investigation. This is a UNESCO-sponsored project, conducting research into Manichaean and Christian missionary activities around the port city of Quanzhou (Zaitun) in the 12th and 13th centuries. The research is being conducted in conjunction with the Quanzhou Museum of Maritime Contacts, and the results will be published for the Museum in a catalogue of Sy ....Manichaean and Medieval Christian (Nestorian and Catholic) remains in Quanzhou (S. China) - an epigraphical, iconographical and historical investigation. This is a UNESCO-sponsored project, conducting research into Manichaean and Christian missionary activities around the port city of Quanzhou (Zaitun) in the 12th and 13th centuries. The research is being conducted in conjunction with the Quanzhou Museum of Maritime Contacts, and the results will be published for the Museum in a catalogue of Syro-Turkish inscriptions and sepulchral monuments. The catalogue will be accompanied by the first monograph in English on this topic, as well as by interim reports and articles.Read moreRead less
Why conserve genetic variation? Is this misdirected effort or a crucial concern? In attempting to conserve populations of threatened plants, ecosystem managers must prioritise allocation of resources to both immediate and long-term threats, including loss of genetic variation. This study will determine the importance of maintaining existing genetic variation within populations of several species in a major Australian plant group. As well as advancing theory in the area of plant ecological genet ....Why conserve genetic variation? Is this misdirected effort or a crucial concern? In attempting to conserve populations of threatened plants, ecosystem managers must prioritise allocation of resources to both immediate and long-term threats, including loss of genetic variation. This study will determine the importance of maintaining existing genetic variation within populations of several species in a major Australian plant group. As well as advancing theory in the area of plant ecological genetics and evolutionary biology, our results will provide a stronger scientific basis for the development of conservation policy and management decisions for conserving threatened plant species. Read moreRead less
Tracing the origins of stress in the symbionts of reef-building corals. Symbiotic dinoflagellates of corals are critical to the world's major tropical reef ecosystems. Recent work in our laboratories and others has revealed that these algae are sensitive to a wide array of stresses (including climate change) and hence may be the ?Achilles Heel? of reef ecosystems. This project will identify the key genes and processes in these algae using expressed sequence tags and microarray technology. On th ....Tracing the origins of stress in the symbionts of reef-building corals. Symbiotic dinoflagellates of corals are critical to the world's major tropical reef ecosystems. Recent work in our laboratories and others has revealed that these algae are sensitive to a wide array of stresses (including climate change) and hence may be the ?Achilles Heel? of reef ecosystems. This project will identify the key genes and processes in these algae using expressed sequence tags and microarray technology. On this basis, the underlying molecular mechanisms of these stress responses and their genetic diversity will be studied in order to better understand the differential susceptibility of reef-building corals to bleaching.Read moreRead less
A functional genomic approach for understanding metal ion adaptation in marine cyanobacteria. Unicellular marine cyanobacteria constitute 20-40% of total marine chlorophyll biomass and carbon fixation, and hence significantly impact the global carbon cycle and are very relevant to combating global warming. This research will reveal some of the major mechanisms by which marine cyanobacteria have adapted to metal levels in coastal and oligotrophic environments. Thus these results will help us und ....A functional genomic approach for understanding metal ion adaptation in marine cyanobacteria. Unicellular marine cyanobacteria constitute 20-40% of total marine chlorophyll biomass and carbon fixation, and hence significantly impact the global carbon cycle and are very relevant to combating global warming. This research will reveal some of the major mechanisms by which marine cyanobacteria have adapted to metal levels in coastal and oligotrophic environments. Thus these results will help us understand the distribution and diversity of these organisms in relation to global primary productivity. They will also lead to the development of more robust biomarkers for metal stress and pollution in coastal environments.Read moreRead less
Organisation, expression and diversity of the sub-telomeric regions of the ancient eukaryote, Giardia duodenalis. We propose to extend our findings on the extreme plasticity of the structure and organisation of the sub-telomeric region of the complete genome of Giardia by more extensive chromosome walking, and comparison of different isolates. These regions are subject to gene conversion, transcriptional silencing, gene mobility, recombination, variable surface protein expression, subtelomeric i ....Organisation, expression and diversity of the sub-telomeric regions of the ancient eukaryote, Giardia duodenalis. We propose to extend our findings on the extreme plasticity of the structure and organisation of the sub-telomeric region of the complete genome of Giardia by more extensive chromosome walking, and comparison of different isolates. These regions are subject to gene conversion, transcriptional silencing, gene mobility, recombination, variable surface protein expression, subtelomeric instability and the insertion of transposable elements, a dynamic balance between structural conservation and rapid evolution. This is a rare opportunity to understand the forces at work in moulding eukaryotic sub-telomeric sequences because Giardia is not constrained by sexual homogenisation and the dynamic variability is retained.Read moreRead less
Mechanosensitive properties and modulation of N-methyl-D-aspartate (NMDA) receptors by lipid environment. This project will provide new information about the molecular determinants which influence NMDA receptor channel gating that will significantly advance our understanding of a link between NMDA receptor function and many neurodegenerative diseases as well as pain and learning and memory. The outcomes of this project may lead to the discovery of novel lipid-based biomaterials for application i ....Mechanosensitive properties and modulation of N-methyl-D-aspartate (NMDA) receptors by lipid environment. This project will provide new information about the molecular determinants which influence NMDA receptor channel gating that will significantly advance our understanding of a link between NMDA receptor function and many neurodegenerative diseases as well as pain and learning and memory. The outcomes of this project may lead to the discovery of novel lipid-based biomaterials for application in medicine and the drug industry. This research is highly significant in relation to human health. The biological and nutritional aspects of polyunsaturated lipids and dietary fish oils have long been recognized. Thus this project will provide further knowledge that could benefit the health of the nation with consequent reduced health care costs.Read moreRead less