Identification Of Glaucoma Susceptibility Variants By Exome Sequencing In Extended Pedigrees Showing Prior Evidence Of Gene Segregation.
Funder
National Health and Medical Research Council
Funding Amount
$694,002.00
Summary
Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for tr ....Primary open angle glaucoma is a chronic eye disease and one of the leading causes of visual impairment and blindness worldwide. This study will use cutting-edge genetic methods to look at the entire coding component of the human genome (exome) in 271 individuals from large glaucoma families. Our previous studies have shown that these families carry genetic variants that increase disease risk. In this investigation we aim to identify these genes, with the hope they may offer novel targets for treatment or diagnosis.Read moreRead less
A Genome-wide Association Study In 2000 Glaucoma Cases With Matched Controls Using Equimoloar DNA Pools
Funder
National Health and Medical Research Council
Funding Amount
$610,267.00
Summary
Glaucoma is a common cause of loss of vision worldwide but we are unable to predict which people are at high risk of blindness. We aim to discover the genetic risk factors for glaucoma. We will use cutting edge genetic technology to assess the whole genome in thousands of patients with glaucoma. We hope to identify important new glaucoma genes, which could lead to the development of diagnostic tests and treatments which will provide the most cost-efficient ways to prevent glaucoma blindness.
Empowering Aboriginal & Torres Strait Islander Girls, Changing Communities. This project applies Indigenous knowledges to develop new understandings and insights in the area of Aboriginal and Torres Strait Islander girls’ education. Expected outcomes of the project include: the development of a national framework that supports the education of girls and acknowledges the importance of self-determination, culture, gender and place in creating life changing educational opportunities; addressing Clo ....Empowering Aboriginal & Torres Strait Islander Girls, Changing Communities. This project applies Indigenous knowledges to develop new understandings and insights in the area of Aboriginal and Torres Strait Islander girls’ education. Expected outcomes of the project include: the development of a national framework that supports the education of girls and acknowledges the importance of self-determination, culture, gender and place in creating life changing educational opportunities; addressing Close the Gap targets; and creating broader long lasting positive changes regarding access, participation and success for Aboriginal and Torres Strait Islander students. The outcomes of this project can provide significant benefits to the broad Australian schooling system.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100048
Funder
Australian Research Council
Funding Amount
$499,899.00
Summary
Foundations of the common law library. This project aims to build a comprehensive, historical, legal resource for the whole common law world, 1215-1914. The free access ‘Foundations of Common Law Library’ will include reported cases from superior courts, and selected others, in all common law jurisdictions. Databases of other key materials such as treatises, legislation, and treaties, will also be added wherever possible. Databases of case law extracted from newspaper reports, prior to formal la ....Foundations of the common law library. This project aims to build a comprehensive, historical, legal resource for the whole common law world, 1215-1914. The free access ‘Foundations of Common Law Library’ will include reported cases from superior courts, and selected others, in all common law jurisdictions. Databases of other key materials such as treatises, legislation, and treaties, will also be added wherever possible. Databases of case law extracted from newspaper reports, prior to formal law reporting will be included. Citations for all documents added will expand greatly an automated international historical citator to the whole of the common law world, linking past and present.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100051
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
The Australasian Legal History Libraries: Stage II. The Australasian legal history libraries stage II: Australia's leading legal historians will partner with the Australasian Legal Information Institute (AustLII) to create a massive expansion of free online access to Australasian legal history through digitisation and data aggregation. The Legal History Libraries on AustLII will become a comprehensive trans-Tasman collection from 1788-1999, including all reported case series and those from colon ....The Australasian Legal History Libraries: Stage II. The Australasian legal history libraries stage II: Australia's leading legal historians will partner with the Australasian Legal Information Institute (AustLII) to create a massive expansion of free online access to Australasian legal history through digitisation and data aggregation. The Legal History Libraries on AustLII will become a comprehensive trans-Tasman collection from 1788-1999, including all reported case series and those from colonial newspaper reports, and all Acts enacted, plus key collections of historical Bills, Gazettes, legal commentaries, and Parliamentary reports. The Libraries are expected to double in size from their current 50,000 items of cases and legislation. The Libraries will enable previously impractical access, comparative research, and international collaborations.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100040
Funder
Australian Research Council
Funding Amount
$447,127.00
Summary
Unravelling the genetics of Kangaroo paws for climate-resilient gardens. The project will produce the first DNA-anchored plant lineage map of Kangaroo paws and gain novel insights into their resilient growth characteristics. Using novel genome and data-driven strategies, this project addresses the knowledge gap around the genetic heirloom of more than 200 iconic Kangaroo paw varieties to speed up the breeding of new varieties with enticing leaf patterns and flower colour combinations. While unra ....Unravelling the genetics of Kangaroo paws for climate-resilient gardens. The project will produce the first DNA-anchored plant lineage map of Kangaroo paws and gain novel insights into their resilient growth characteristics. Using novel genome and data-driven strategies, this project addresses the knowledge gap around the genetic heirloom of more than 200 iconic Kangaroo paw varieties to speed up the breeding of new varieties with enticing leaf patterns and flower colour combinations. While unravelling the inheritability and breeding barriers, immediate industry adoption will boost horticultural breeding programs long-term. This project uses cutting-edge science to enhance industry capacity for providing new Kangaroo paws for climate-resilient urban green spaces on the national and international market.Read moreRead less