A Randomised Control Trial Of A Group-Based Intervention For Substance Abuse In Psychosis.
Funder
National Health and Medical Research Council
Funding Amount
$345,250.00
Summary
The use of alcohol and illicit substances is common amongst people with psychotic illnesses, and is associated with a poor outcome in terms of severity of symptoms, treatment adherence, work-studies, family cohesion, aggression and quality of life. All this adds significantly to the cost of mental health services and society more broadly. The proposed study aims to refine, pilot, and rigorously evaluate a group-based intervention that targets substance use in such individuals at different stages ....The use of alcohol and illicit substances is common amongst people with psychotic illnesses, and is associated with a poor outcome in terms of severity of symptoms, treatment adherence, work-studies, family cohesion, aggression and quality of life. All this adds significantly to the cost of mental health services and society more broadly. The proposed study aims to refine, pilot, and rigorously evaluate a group-based intervention that targets substance use in such individuals at different stages of their illness, and within a number of different treatment settings. The intervention will be informed by an enhanced understanding of the motivations for substance use in people with psychotic illnesses The specific aims are to: Refine, implement and evaluate, using a controlled experimental design, a novel group-based intervention for reducing substance abuse comorbidity in people with psychotic disorders; Determine reasons for substance use by these individuals, to inform the intervention procedures; Pilot the intervention in a series of different treatment settings, including early episode and rehabilitation programs, and non-government organisations dealing with people with psychotic disorders, to ensure generalisability, adaptability, and acceptability; Augment case managers' knowledge and skills in dealing with comorbid drug and alcohol use Enhance detection, motivation to change, ongoing monitoring and relapse prevention of substance misuse in clients with psychotic disorders. It will also be possible, once the treatment intervention is finalised and evaluated, to expand its use to patients with non-psychotic mental illnesses.Read moreRead less
Evaluation Of Cognitive-behaviour Therapy For Alcohol And Other Drug Problems Among People With A Psychotic Illness
Funder
National Health and Medical Research Council
Funding Amount
$217,465.00
Summary
Abuse of alcohol and other drugs among people with a major psychiatric illness is a serious public health problem and cost-effective treatments need to be developed and assessed. The aim of this project is to evaluate the effectiveness of a counselling intervention. 180 individuals with a psychotic illness and concurrent alcohol and other drug (AOD) problems will be randomly assigned to counselling or usual treatment and followed up for a period of 12 months. The indicators of interest include: ....Abuse of alcohol and other drugs among people with a major psychiatric illness is a serious public health problem and cost-effective treatments need to be developed and assessed. The aim of this project is to evaluate the effectiveness of a counselling intervention. 180 individuals with a psychotic illness and concurrent alcohol and other drug (AOD) problems will be randomly assigned to counselling or usual treatment and followed up for a period of 12 months. The indicators of interest include: current drug use; psychiatric symptoms; self-harm; social functioning; and use of health services. Findings from the proposed study will assist in the selection of particular treatment strategies and will aid the overall development of services for people with both major mental illness and substance abuse.Read moreRead less
Single-focussed Versus Integrated Cognitive Behaviour Therapy For Co-occurring Depression And Alcohol Use Problems
Funder
National Health and Medical Research Council
Funding Amount
$777,500.00
Summary
This study is significant and timely in that it proposes a large-scale randomised controlled trial of cognitive behaviour therapy (CBT) for people with co-occurring depression and alcohol use problems. To date, very few researchers have conducted research within this population, whose complex presentation makes it difficult for treatment providers to select and deliver effective treatment programs. Thus, although rates of depressive disorders and alcohol use problems are on the increase in our c ....This study is significant and timely in that it proposes a large-scale randomised controlled trial of cognitive behaviour therapy (CBT) for people with co-occurring depression and alcohol use problems. To date, very few researchers have conducted research within this population, whose complex presentation makes it difficult for treatment providers to select and deliver effective treatment programs. Thus, although rates of depressive disorders and alcohol use problems are on the increase in our community, it is still not clear how best to manage and treat this group of people. Typically, people will often receive treatment for one part of their presentation, for example their depression or alcohol use problem. However, it is uncommon for the two conditions to be treated in an integrated way. This is certainly true for psychological treatments. Research programs to date have explored effective treatments for depression and alcohol use in the absence of the co-occurring condition. Currently it is not known how well people with co-occurring alcohol use problems and depression respond to treatments with a singular focus. Furthermore, it is not known whether integrating both alcohol use and depressive treatment approaches provides any additional benefit. This study is therefore significant, as it is one of the first to explore effective treatment approaches among people with co-occurring depressive and alcohol use problems. Resolution of these issues will better inform the treatment choices of clinicians practicing in both mental health and alcohol-other drug settings. Importantly, this will potentially improve the match between treatment and people with depression and substance use problems, a clinically prevalent population encountered in community settings.Read moreRead less
Improved Treatment Of Comorbid Anxiety And Depression In Adolescents: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$275,250.00
Summary
Anxiety and depression are serious mental disorders that affect large numbers of children and adolescents in our community. In particular, young people with both anxiety and depression may experience severe difficulties including poor physical health, social and interpersonal problems, academic problems, drug and alcohol problems, long-term adjustment problems and suicidal behaviour. Although a range of very effective treatments have been developed to treat anxiety and depression separately, the ....Anxiety and depression are serious mental disorders that affect large numbers of children and adolescents in our community. In particular, young people with both anxiety and depression may experience severe difficulties including poor physical health, social and interpersonal problems, academic problems, drug and alcohol problems, long-term adjustment problems and suicidal behaviour. Although a range of very effective treatments have been developed to treat anxiety and depression separately, there is very little work on the treatment of young people with both these problems. Some studies suggest that youth with both anxiety and depression together do worse in currently available treatments, compared to their peers with only a single condition. The current grant seeks to test whether a new treatment addressing both anxiety and depression concurrently, is superior to standard treatments for adolescents experiencing both these emotional problems. It is predicted that the addition of extra components to standard treatments, will result in considerably greater improvements in these more complex cases.Read moreRead less
Towards An Etiological Understanding Of The Comorbidity Of Psychiatric Disorders
Funder
National Health and Medical Research Council
Funding Amount
$997,883.00
Summary
Pyschiatric disorders are common disorders with both genetic and environmental etilogy. The disorders are characterised both by significant overlap of symptoms and by significant heterogenity of symptoms within disorders. The availability of genome-wide genotypes allows us, for the first time, to investigate co-morbidity directly at the molecular level. Understanding the nature of co-morbidity between disorders nay be an important key to effective treatment.
Randomised Controlled Trial Of Treatment For Alcohol Use Problems And Social Phobia
Funder
National Health and Medical Research Council
Funding Amount
$630,333.00
Summary
Social Phobia and harmful Alcohol use often go together and suferers experince additional distress, disability, and worse results from treatment. Previous clinical trials tested adding treatments for the separate disorders together which may have confused patients. This project test integrated evidence based CBT treatments for the separate problems compared to treatment for alcohol alone. Reduced drinking, decreased social anxiety and increased quality of life are the expected results
A Comparative Study: Patterns Of Care, Comorbidities And Quality Of Life Of Indigenous And Non-Indigenous People With Lung, Head & Neck, Breast Or Gynaecological Cancers
Funder
National Health and Medical Research Council
Funding Amount
$691,814.00
Summary
Indigenous people with cancer have higher mortality rates and poorer survival than other Australians. Cancer treatment is complex, involves many therapies; there are many opportunities for someone to become �lost� in the system, causing unnecessary morbidity and personal distress. This study will compare the treatment and management of Indigenous cancer patients against �best practice� guidelines with the aim of identifying factors that are modifiable (i.e. health services, treatment patterns).