Integration And Expansion Of A Sentinel Surveillance System To Improve Infectious Disease Outcomes For Indigenous Australians; The ATLAS Network
Funder
National Health and Medical Research Council
Funding Amount
$1,137,219.00
Summary
Infectious diseases remain a significant health issue for Indigenous Australians. Our proposal is to extend a sentinel surveillance network operating in 32 Aboriginal primary care services, with a focus on sexually transmissible infections and blood borne virsuses. By expanding, we will increase the number of sites, and add vaccine preventable diseases to the network. In doing this, we move from a surveillance system to a research network that can inform health service strategies and practice.
Guiding Intervention Choices To Reduce Health Costs, Health Inequalities, And Improve The Health Of Australians
Funder
National Health and Medical Research Council
Funding Amount
$3,200,000.00
Summary
As health care costs rise, governments increasingly will need objective evidence on the benefits and costs of health intervention options, whilst taking into account the need for greater health equity, transparency of decision making and stakeholder acceptability. This project will provide the health intelligence to guide such health priority setting in Australia, with a focus on prevention of non-communicable diseases, the implications for Indigenous Australians and the most efficient ways of i ....As health care costs rise, governments increasingly will need objective evidence on the benefits and costs of health intervention options, whilst taking into account the need for greater health equity, transparency of decision making and stakeholder acceptability. This project will provide the health intelligence to guide such health priority setting in Australia, with a focus on prevention of non-communicable diseases, the implications for Indigenous Australians and the most efficient ways of implementing priority interventions in primary care.Read moreRead less
The Elimination Of Viral Hepatitis And Ending HIV/AIDS As Global Health Threats.
Funder
National Health and Medical Research Council
Funding Amount
$2,114,215.00
Summary
Over the next five years my research will focus on reducing the impact of blood-borne viruses (BBVs), , particularly HCV, in vulnerable populations. Using innovative surveillance systems, research methods, implementation science and mathematical modelling, I will study BBV transmission and develop interventions to reduce it and associated risk behaviours (drug and alcohol use and sexual risk) and increase testing and treatment. My work will advance elimination of BBVs as public health threats.
Australian Centre For Research Excellence In Aboriginal Sexual Health And Blood Borne Viruses
Funder
National Health and Medical Research Council
Funding Amount
$2,496,848.00
Summary
Despite efforts to improve sexual health and blood borne virus outcomes for Aboriginal people over the last twenty years, this area lacks national coordination, has critical research gaps and requires a boost of research capacity to address the burden of diseases. This CRE will address research gaps, using novel, multidisciplinary methods and using unique research translation methods to ensure policy and practice benefits from the CRE outcomes.
Hepatitis C affects between 1-3% of Australians. Currently, there is no effective vaccine and only 30% will spontaneously clear infection, while the remained develop a chronic disease with a small risk of progression to liver cirrhosis and liver cancer over time. This study aims to evaluate the safety and efficacy of a two different treatment regimens among individuals with recent Hepatitis C infection; and define the risk factors and natural history of Hepatitis C superinfection during treatmen ....Hepatitis C affects between 1-3% of Australians. Currently, there is no effective vaccine and only 30% will spontaneously clear infection, while the remained develop a chronic disease with a small risk of progression to liver cirrhosis and liver cancer over time. This study aims to evaluate the safety and efficacy of a two different treatment regimens among individuals with recent Hepatitis C infection; and define the risk factors and natural history of Hepatitis C superinfection during treatment.Read moreRead less
Reducing The Impact Of Blood Borne Viruses And Sexually Transmitted Infections In Young People.
Funder
National Health and Medical Research Council
Funding Amount
$851,980.00
Summary
Over the next five years I will undertake a program of research centred on reducing the impact of blood-borne viruses and sexually transmitted infections in vulnerable populations, particularly focusing on HCV and HIV elimination. I will use innovative systems and methods to study how these infections are transmitted and develop interventions that reduce disease transmission and associated risk-behaviours (drug and alcohol use and sexual behaviours) and increased testing and treatment.
Improving Understanding Of Psychostimulant-related Harms In Australia: An Integrated Ethno-epidemiological Approach
Funder
National Health and Medical Research Council
Funding Amount
$612,430.00
Summary
National drug surveys and surveillance systems have detected sharp increases in the use of 'psychostimulant' drugs such as the amphetamines, ecstasy and cocaine. The level of harms associated with excessive use of these drugs, such as mental health problems and drug dependence, has also increased, as has the use of these drugs via injection. These increases in the prevalence of use and related harms have also been detected internationally. Previous research on psychostimulant drugs, in Australia ....National drug surveys and surveillance systems have detected sharp increases in the use of 'psychostimulant' drugs such as the amphetamines, ecstasy and cocaine. The level of harms associated with excessive use of these drugs, such as mental health problems and drug dependence, has also increased, as has the use of these drugs via injection. These increases in the prevalence of use and related harms have also been detected internationally. Previous research on psychostimulant drugs, in Australia and overseas, has suggested that using these drugs in particular ways might be associated with a greater chance of contracting HIV and other blood-borne viruses such as hepatitis C (eg through sharing needles and syringes or other equipment associated with injecting drugs); sexually transmitted infections and other sexual health problems (eg through engaging in unsafe sex); and of being involved in violent incidents. Despite this previous research, however, little is known about the specific social and cultural contexts associated with psychostimulant-related harms, and this has stymied the development of appropriate responses to prevent such harms occurring. This research project will provide a greater understanding of the individual, social and cultural factors associated with pychostimulant-related harm through an innovative combination and integration of anthropological and epidemiological research methods known as 'ethno-epidemiology'. In order to access a range of psychostimulant-using contexts, research will focus on three sites: street-based drug users in Sydney, club drug users in Melbourne, and home-based recreational drug users in Perth. These groups have been chosen because they have high prevalences of psychostimulant use. The research project will provide important data that will inform future interventions, improve multidisciplinary models for drug research, and build Australia's capacity to conduct cutting-edge public health research.Read moreRead less
Understanding The Barriers To Improved Access, Engagement And Retention Of Methamphetamine Users In Health Services
Funder
National Health and Medical Research Council
Funding Amount
$788,291.00
Summary
Drug surveys show widespread use of methamphetamine. Its regular use, particularly via injection, is associated with a range of serious harms, including drug dependence, psychosis, viral infection and violence. In order to improve access, engagement and retention of methamphetamine injectors in drug treatment and other health services, and thereby reduce these harms, further research is urgently needed to better understand their healthcare needs and the existing barriers to service utilisation.
Preventing Mortality In Adults After Release From Prison: Advancing Global Knowledge Through An International, Individual Participant Data Meta-analysis
Funder
National Health and Medical Research Council
Funding Amount
$613,687.00
Summary
Ex-prisoners are at increased risk of death, but not enough is known about the incidence, timing, causes, context or risk factors for preventable death in this population. In this project we have compiled 18 cohorts of ex-prisoners (total number=1,159,290) and will analyse the data to determine exactly which ex-prisoners are at the greatest risk from what, and when. This new knowledge will inform policy changes to reduce the unnecessary loss of life in this vulnerable population.