Providing Translatable Evidence To Advance Prevention And Management Of COPD: A Longitudinal Study From The 1st To 7th Decade Of Life
Funder
National Health and Medical Research Council
Funding Amount
$2,893,320.00
Summary
Chronic obstructive pulmonary disease (COPD) makes breathing difficult and reduces wellbeing. People are more likely to get COPD from the age of 60 years, but we do not know why and who. Our study will develop tools to identify early who will develop COPD by 60 years. We will also develop a tool to identify 60-year-old individuals whose lung function is declining faster than normal. These findings will help us to better prevent and manage COPD.
The PREDICT study will fill a very important gap in our understanding of diabetes. By studying what happens to over 3,000 people with type 2 diabetes over the next decade, it will identify improved ways of identifying which people with diabetes will develop its devastating complications. This will allow targeting of intensive treatment on those who need it the most, and will also provide an important means of identifying potential new ways of treating and supporting people with type 2 diabetes.
A Randomised Controlled Trial Of N-acetylcysteine For The Treatment Of Alcohol Use Disorder
Funder
National Health and Medical Research Council
Funding Amount
$1,294,923.00
Summary
We urgently require new treatment strategies. Alcohol misuse is a leading cause of preventable death yet treatment options are limited. We will undertake the first human trial of N-acetylcysteine (NAC) for the management of alcohol use disorder (NAC-AUD). The NAC-AUD project will evaluate the efficacy and cost-efficacy of NAC to reduce alcohol consumption. The results will generate high level clinical evidence for a safe new treatment for a common life threatening disease.