The vision we rely on every day to read and recognise faces depends upon the health of the central portion of our retina, the macula. Age-related Macular Degeneration (AMD) is the leading cause of blindness in Australia and the western world. Researchers at the Australian National University are collaborating to bring a new test for AMD severity to the market within 3 years. The objective is to provide doctors with a rapid, cost-effective tool to help them manage treatment.
Validation Of A Multiplexed Blood Based Screening Assay For The Diagnosis Of Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$556,712.00
Summary
Colorectal cancer (CRC) is the second most common cancer in Australia with poor patient outcome due to late detection of the disease. We have developed a simple blood based test that can diagnose individuals with CRC at an early stage when the chance of cure is greater than 80%.
Uncovering The Basis Of Inflammatory And Immunodeficiency Diseases
Funder
National Health and Medical Research Council
Funding Amount
$15,718,075.00
Summary
A world-class team from 3 institutions, spanning disciplines of clinical and experimental immunology, therapeutics, signalling and genetics, will identify how immune and inflammatory responses are controlled in both health and disease. The major outcomes of this work will be the generation of new knowledge, concepts and approaches to diagnose, prevent and treat the major human health problems of autoimmune diseases, inflammation, allergy and immunodeficiency.
Modelling human decision making in complex environments. The project aims to extend quantitative psychological models of simple choice tasks to decision-making with complex stimuli in complex environments. The new formal models are designed to provide a comprehensive account of behaviour, including the choices that are made, how long it takes to make them, and how choices and choice times vary within and between decision-makers. The models would explain how people adapt to changes in task demand ....Modelling human decision making in complex environments. The project aims to extend quantitative psychological models of simple choice tasks to decision-making with complex stimuli in complex environments. The new formal models are designed to provide a comprehensive account of behaviour, including the choices that are made, how long it takes to make them, and how choices and choice times vary within and between decision-makers. The models would explain how people adapt to changes in task demands when dealing with multiple stimuli or performing multiple tasks concurrently under time pressure. The project aims to provide the basic research that is needed to extend psychological models of choice to complex ‘real-world’ tasks, such air traffic control and maritime surveillance.Read moreRead less
Creating a climate for change: from cognition to consensus. Climate change is a significant contemporary issue, and communicating the complexities of the terminology and the data is a major modern challenge. This project will apply principles of cognitive and social psychology to determine the most effective methods for promoting an understanding of the scientific dimensions of the issue. The research is significant because it provides a coherent theoretical framework for identifying the psychol ....Creating a climate for change: from cognition to consensus. Climate change is a significant contemporary issue, and communicating the complexities of the terminology and the data is a major modern challenge. This project will apply principles of cognitive and social psychology to determine the most effective methods for promoting an understanding of the scientific dimensions of the issue. The research is significant because it provides a coherent theoretical framework for identifying the psychological mechanisms underlying cognition and commitment at both an individual and collective level. The outcome will be a body of evidence that will inform strategies and policies for communication of complex scientific questions.Read moreRead less
Spatial Cognition—Expressive Representation Formalisms and Effective Reasoning Mechanisms. The project will contribute significantly to the advancement of knowledge in breakthrough science in qualitative spatial reasoning and smart information use in geographic information systems. Expressive spatial languages are important in organising spatial knowledge, defining spatial query languages and guiding spatial data mining. Effective spatial reasoning mechanisms bring theory closer to applications ....Spatial Cognition—Expressive Representation Formalisms and Effective Reasoning Mechanisms. The project will contribute significantly to the advancement of knowledge in breakthrough science in qualitative spatial reasoning and smart information use in geographic information systems. Expressive spatial languages are important in organising spatial knowledge, defining spatial query languages and guiding spatial data mining. Effective spatial reasoning mechanisms bring theory closer to applications including consistency checking and spatial query pre-processing. The project will help in extracting knowledge from massive spatial databases, meeting the growing needs of naive users for spatial information and establishing Australia as a major player in spatial cognition research and in the development of geo-location services.Read moreRead less
The Role And Inheritance Of Constitutional Epimutations In Early-onset Colorectal Cancer.
Funder
National Health and Medical Research Council
Funding Amount
$347,551.00
Summary
Traditionally familial cancers are thought to be caused by spelling mistakes within the genetic code of cancer prevention genes. Our group has found that chemical attachments to one gene (MLH1) stops it working, even where there is no spelling mistake, and that those chemical changes can be inherited in families with bowel cancer. We will determine how frequently this type of defect occurs in bowel cancer patients, how and why it arises, and if other cancer genes are similarly affected.
Judgements and Decisions under Ambiguity and Conflict. Little is known about how people make decisions when faced with uncertainties arising from information that is both ambiguous and conflicting, despite the fact that ambiguity and conflict frequently arise in real decision-making situations. In fact, virtually nothing is known about the joint impact of conflict and ambiguity on judgements of risk and uncertainty or on decisional preferences. This project will investigate how perceptions of un ....Judgements and Decisions under Ambiguity and Conflict. Little is known about how people make decisions when faced with uncertainties arising from information that is both ambiguous and conflicting, despite the fact that ambiguity and conflict frequently arise in real decision-making situations. In fact, virtually nothing is known about the joint impact of conflict and ambiguity on judgements of risk and uncertainty or on decisional preferences. This project will investigate how perceptions of uncertainty are jointly affected by conflict and ambiguity in information, develop and test formal models of judgement and decision making under conflict and ambiguity, and examine the joint effects of ambiguity and conflict aversion on decision making.Read moreRead less
Zero-sum thinking: psychological predictors and causes. This project investigates the causes and psychological triggers of zero-sum thinking, the tendency to think that others' gains leave less for oneself. The results will enable negotiators and managers to defuse dysfunctional zero-sum thinking, thereby increasing the chances for cooperation and 'win-win' outcomes.
AusDiab 3: Emerging Risk Factors For And Long-term Incidence Of Cardio-metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,616,397.00
Summary
This study will track 11,000 Australian adults over 12 years to determine how many develop diabetes, obesity, kidney and heart disease. The study will develop ways to best predict those who are going to develop these conditions before they have arisen, and will explore a range of novel risk factors to better understand these conditions.