Probing cross modal interactions in the perception of object motion and self-motion. How the brain integrates information from the different senses is not yet understood. This project aims first, to uncover how the brain integrates sound and visual information when perceiving moving objects and second, to probe more complex sensory interactions between sound, vision, and our vestibular senses when perceiving self-motion. This project will expand Australia's knowledge base, strengthen collabora ....Probing cross modal interactions in the perception of object motion and self-motion. How the brain integrates information from the different senses is not yet understood. This project aims first, to uncover how the brain integrates sound and visual information when perceiving moving objects and second, to probe more complex sensory interactions between sound, vision, and our vestibular senses when perceiving self-motion. This project will expand Australia's knowledge base, strengthen collaborative ties between Australia and Japan, and provide unique training opportunities for Australian and Japanese students. Publication of research in top-ranking journals will further promote Australian science abroad. Results will lead to improvements in the design of human-machine interfaces in both industry and entertainment.Read moreRead less
Mechanisms of learning at the interface between perception and action. Using the latest in brain imaging and simulator technology, this project will advance understanding of how experience shapes the visual centres of our brain. It will also support partnerships with construction, mining and health services by developing real and virtual machine interfaces and tools to enhance the outcome of simulator-based training.
Discovery And Development Of Better Pain Treatments
Funder
National Health and Medical Research Council
Funding Amount
$9,613,850.00
Summary
Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clini ....Many forms of pain remain poorly treated, leading to significant quality of life and economic losses. This Program grant will discover and characterise new peptides from cone snails and spiders that modulate specific channels in nerves that are critical to the transmission of pain signals to the brain. Using advanced chemical and structural approaches, promising leads will be optimised for potency and stability and evaluated in disease and pathway-specific models of pain to establish their clinical potential.Read moreRead less
The role of the immune system in pain is emerging from recent discoveries, and may hold the key to novel pain treatments. Most people experience brief gut infections from food or contagion without long-term consequences. Many others suffer symptoms for years afterwards - probably the best example of immune-based pain. Our project investigates how immune cells communicate with sensory nerves, and how these communications change from both angles after gut infection or inflammation.
Discovery Early Career Researcher Award - Grant ID: DE190100136
Funder
Australian Research Council
Funding Amount
$385,288.00
Summary
The influence of naturalistic context on visual short-term memory. This project aims to understand visual short-term memory in natural visual environments using a combination of behavioural and brain data. Visual short-term memory is thought to be critical to complex cognitive tasks such as learning and problem solving, but how low-level image context and high-level semantic information influence short-term memory is poorly understood. This project will use advanced computational image processin ....The influence of naturalistic context on visual short-term memory. This project aims to understand visual short-term memory in natural visual environments using a combination of behavioural and brain data. Visual short-term memory is thought to be critical to complex cognitive tasks such as learning and problem solving, but how low-level image context and high-level semantic information influence short-term memory is poorly understood. This project will use advanced computational image processing tools, neuro-imaging, and psychophysical experiments to provide a comprehensive analysis of short-term memory in naturalistic images. The expected outcome is a better understanding of the neural bottlenecks that limit short-term memory, and a model that predicts memory constraints in natural visual environments.Read moreRead less
How do bees orchestrate smooth landings? The results should pave the way for the development of novel, biologically inspired strategies for the control of landing in unmanned aerial vehicles. Endowing aircraft with the capability of autonomous flight and landing has been a major challenge in engineering technology. There is now considerable interest, nationally and world wide, in the development of small, intelligent, autonomous airborne vehicles for application in a number of areas of defense, ....How do bees orchestrate smooth landings? The results should pave the way for the development of novel, biologically inspired strategies for the control of landing in unmanned aerial vehicles. Endowing aircraft with the capability of autonomous flight and landing has been a major challenge in engineering technology. There is now considerable interest, nationally and world wide, in the development of small, intelligent, autonomous airborne vehicles for application in a number of areas of defense, surveillance and space exploration. The proposed research will help Australia maintain a leading edge in uncovering important biological principles of flight control that can be translated into useful technological applications.Read moreRead less
Linking human brain structure to function with ultra-high resolution fMRI. This project will examine the structure and function of the sensory cortex of the human brain using ultra-high resolution functional magnetic resonance imaging (7 Tesla MRI). The project pushes new boundaries for resolution with ultra-high field MRI (7 Tesla) and, as such, will advance techniques for the acquisition, analysis, and computational modelling of high-resolution fMRI brain imaging, providing detail of the funct ....Linking human brain structure to function with ultra-high resolution fMRI. This project will examine the structure and function of the sensory cortex of the human brain using ultra-high resolution functional magnetic resonance imaging (7 Tesla MRI). The project pushes new boundaries for resolution with ultra-high field MRI (7 Tesla) and, as such, will advance techniques for the acquisition, analysis, and computational modelling of high-resolution fMRI brain imaging, providing detail of the functional organisation of the sensory cortex at a level never previously possible in the living human brain. This will provide new understanding of the neural-level networks that underpin attention and touch perception in the human brain.Read moreRead less
Perception of pain in simple nervous systems. Research over the past twenty years has revealed that cognitive behaviour in honeybees is much more sophisticated than hitherto assumed. The next frontier is to investigate whether these creatures are capable of experiencing pain. This study will measure the concentrations of biogenic amines and peptides in the haemolymph of injured honeybees, and the preferences of wounded individuals for pain killers to investigate whether bees are capable of exper ....Perception of pain in simple nervous systems. Research over the past twenty years has revealed that cognitive behaviour in honeybees is much more sophisticated than hitherto assumed. The next frontier is to investigate whether these creatures are capable of experiencing pain. This study will measure the concentrations of biogenic amines and peptides in the haemolymph of injured honeybees, and the preferences of wounded individuals for pain killers to investigate whether bees are capable of experiencing a sensation of pain. If the answer is positive, insects may provide new and simple models for the study of pain, and the results could lead to the formulation of guidelines for ethical experimentation with certain classes of invertebrates.Read moreRead less
Motion and Spatial Coding in Vision. The results of this project will have implications for the design and implementation of artificial visual systems. Completion of this project will depend upon international collaboration - forging links between a young Australian investigator and outstanding overseas scientists as well as providing excellent training opportunities. Subsequent publication of the research in top-ranking international journals will further promote Australian science abroad.
HIDE AND SPEAK - COLOUR COMMUNICATION IN REEF FISH. Fish play an important role in many Australian's lives, they are a source of recreation for scuba divers, snorkelers and fishermen, they are a draw card for tourists as well as a healthy source of food. This project will investigate the visual world of fish, unravelling their use of colour communication, thereby identifying environmental factors affecting successful communication. Such a study will provide insight into the impact on reef fish o ....HIDE AND SPEAK - COLOUR COMMUNICATION IN REEF FISH. Fish play an important role in many Australian's lives, they are a source of recreation for scuba divers, snorkelers and fishermen, they are a draw card for tourists as well as a healthy source of food. This project will investigate the visual world of fish, unravelling their use of colour communication, thereby identifying environmental factors affecting successful communication. Such a study will provide insight into the impact on reef fish of changes in water quality (e.g. river runoff) and temperature (e.g. bleaching events), as well as factors that affect the successful rearing of fish in aquaculture.
Read moreRead less