Do Exposures Before Conception Influence The Risk Of Asthma In Offspring?
Funder
National Health and Medical Research Council
Funding Amount
$688,586.00
Summary
Asthma and poor lung function are major causes of public health issues. Emerging evidence suggests adverse exposures even before the conception of a child may cause these conditions. The proposed project is part of an international study across generations to identify these factors. This study will provide novel evidence to guide interventions and identify studies to advance this area further. These original findings will be of great importance both nationally and internationally.
The Psychology of Misinformation—Towards A Theory-driven Understanding. The project aims to develop a psychological theory of misinformation effects. Misinformation influences people’s memory, reasoning and decision-making even after corrections – it thus poses a significant challenge for science and society. Through the combination of systematic experimentation with theory-driven computational modelling, the project will strive to concurrently consider individual-level cognition and the impact ....The Psychology of Misinformation—Towards A Theory-driven Understanding. The project aims to develop a psychological theory of misinformation effects. Misinformation influences people’s memory, reasoning and decision-making even after corrections – it thus poses a significant challenge for science and society. Through the combination of systematic experimentation with theory-driven computational modelling, the project will strive to concurrently consider individual-level cognition and the impact of sociocultural context. It is anticipated that this novel integrative approach will substantially expand our understanding of misinformation effects, and that this theoretical progress will result in the formulation of specific communication strategies to reduce the impact of misinformation on society.Read moreRead less
DYRK1A As A Novel Target For Glioblastoma Therapies
Funder
National Health and Medical Research Council
Funding Amount
$620,294.00
Summary
Glioblastoma is a form of brain cancer that is currently incurable. We have discovered that switching-off an enzyme called DYRK1A (using ‘DYRK1A inhibitors’) kills glioblastoma cells. This therapeutic advantage is even greater when combined with drugs approved for other cancers. This project will develop new DYRK1A inhibitors and examine a novel combination treatment for glioblastoma patients. This could initiate a novel therapy that could significantly extend patients’ lives.
Aspirin For The Prevention Of Cognitive Decline In The Elderly: A Neuro-Vascular Imaging Study (ENVIS-ion) From ASPREE
Funder
National Health and Medical Research Council
Funding Amount
$1,341,232.00
Summary
The ENVIS-ion trial will examine whether Aspirin is effective in delaying the onset of worsening of thinking and memory abilities in healthy older adults. Magnetic resonance imaging (MRI) of brain structure will detect markers of early worsening of thinking and memory abilities. Blood vessels in the back of the eye (retina) share many features with vessels in the brain. We will compare whether aspirin lessens changes over time of features shown with brain MRI and retinal photography.
From fluid intelligence to crystallised expertise: an integrative Bayesian approach. Intelligence is correlated with learning but uncorrelated with most aspects of expertise. Why is this so? Why does the role of intelligence diminish as one becomes more expert at a task? This project examines a broad range of cognitive tasks to provide a concise mathematical description of how intelligence relates to expertise.
AusDiab 3: Emerging Risk Factors For And Long-term Incidence Of Cardio-metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,616,397.00
Summary
This study will track 11,000 Australian adults over 12 years to determine how many develop diabetes, obesity, kidney and heart disease. The study will develop ways to best predict those who are going to develop these conditions before they have arisen, and will explore a range of novel risk factors to better understand these conditions.
ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, s ....ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, strengthen international collaboration, and involve and inform end-point users. It will foster research which responds to the aspirations and needs of older Australians and informs action that can improve experiences of individual and population ageing.Read moreRead less
ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions i ....ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions in science. An essential function of the network will be introducing researchers end users to new tools and broadening the horizons of graduate students.Read moreRead less
Goal orientations, self-regulation and performance: Implications for accelerating learning via goal-setting interventions. This project relates to the priority of strengthening Australia's social and economic fabric. The question of when and why various goals are adaptive versus maladaptive is of fundamental importance for understanding human behaviour. Society benefits from research into this question, because it provides a pathway for tapping into human potential. The results have implications ....Goal orientations, self-regulation and performance: Implications for accelerating learning via goal-setting interventions. This project relates to the priority of strengthening Australia's social and economic fabric. The question of when and why various goals are adaptive versus maladaptive is of fundamental importance for understanding human behaviour. Society benefits from research into this question, because it provides a pathway for tapping into human potential. The results have implications for the development of effective training programs and thus have the potential to influence personal growth and financial stability. The results will have wide application in a variety of industries. Examples include the development of interventions for more rapid training, and the development of performance-management plans for facilitating career advancement.Read moreRead less
Functional links between estuaries and their catchments: How does land use change affect estuarine ecological and bio-geochemical function? Estuaries are iconic recreational areas of high ecological and socio-economic value. Estuarine health is strongly linked to the catchments that feed them, yet we have no detailed understanding of these links. This project will use a number of state of the art approaches to better understand how land use affects estuarine health.