Concepts and control in speech production. While humans produce speech fluently in the course of everyday conversation, comparatively little is understood about the underlying mental processes and brain mechanisms. The overall aim of this project is to investigate how the human brain conceives and controls speech output by using state-of-the-art neuroimaging and brain stimulation techniques. The research aims to contribute novel insights into a key human ability with particular relevance for spe ....Concepts and control in speech production. While humans produce speech fluently in the course of everyday conversation, comparatively little is understood about the underlying mental processes and brain mechanisms. The overall aim of this project is to investigate how the human brain conceives and controls speech output by using state-of-the-art neuroimaging and brain stimulation techniques. The research aims to contribute novel insights into a key human ability with particular relevance for speech disorders such as aphasia, while the methods developed for brain stimulation during imaging of speech production aim to expand Australia's capability and technical innovation in the cognitive neuroscience of language.Read moreRead less
Brain mechanisms of learning in visually-guided movement. Each year 40,000 Australian suffer from stoke with many left with problems of limb function. In understanding and enhancing the conditions that promote motor adaptation, this research will make a significant contribution to the design of programs for rehabilitation of the upper limbs to enhance quality of life and reduced health care costs.
How the brain produces speech: Neuronal oscillations to neuromodulation. Speech is crucial for facilitating human communication through language, yet there is a lack of clarity about where, when and what type of activity occurs in the brain during key stages of production. This project will use intracranial recordings to characterise neuronal oscillations in combination with direct electrical stimulation, functional neuroimaging and non-invasive brain stimulation to establish critical areas and ....How the brain produces speech: Neuronal oscillations to neuromodulation. Speech is crucial for facilitating human communication through language, yet there is a lack of clarity about where, when and what type of activity occurs in the brain during key stages of production. This project will use intracranial recordings to characterise neuronal oscillations in combination with direct electrical stimulation, functional neuroimaging and non-invasive brain stimulation to establish critical areas and their timecourses with millisecond resolution. The outcome will be a better theoretical account of the brain mechanisms involved in spoken production. The benefit of this new theoretical account will be a better basis for prevention of post-surgical language impairment and neuromodulatory treatments after brain injury.Read moreRead less
A more sound approach to the neurobiology of language. How does the brain attain spoken language? Current neurobiological models assume either implicitly or explicitly that there is no relationship between a word's sound and its meaning. Yet considerable evidence shows this strong assumption about the arbitrariness of language is invalid. This project will use a combination of behavioural, neuroimaging and computational studies to characterise how the brain processes statistical regularities in ....A more sound approach to the neurobiology of language. How does the brain attain spoken language? Current neurobiological models assume either implicitly or explicitly that there is no relationship between a word's sound and its meaning. Yet considerable evidence shows this strong assumption about the arbitrariness of language is invalid. This project will use a combination of behavioural, neuroimaging and computational studies to characterise how the brain processes statistical regularities in sound-to-meaning correspondences as probabilistic cues to attain spoken language. The outcome will be a better neural account of language comprehension and production. The benefit of this new account will be a stronger basis for assessment and treatment of developmental and acquired language impairments.Read moreRead less
How does electrical stimulation affect brain networks? This project aims to generate fundamental knowledge about links between neural mechanisms, electrical brain stimulation and brain function. The project aims to improve knowledge about transcranial direct current stimulation (tDCS) and its effects on complex human brain networks. Such knowledge is necessary to enhance the effectiveness of current stimulation protocols. Using the innovative and interdisciplinary approach, this project will pr ....How does electrical stimulation affect brain networks? This project aims to generate fundamental knowledge about links between neural mechanisms, electrical brain stimulation and brain function. The project aims to improve knowledge about transcranial direct current stimulation (tDCS) and its effects on complex human brain networks. Such knowledge is necessary to enhance the effectiveness of current stimulation protocols. Using the innovative and interdisciplinary approach, this project will provide significant benefits such as crucial mechanistic information about how tDCS modulates healthy brain function which has broad implications for research and clinical use of this technique.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101290
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Age-related reorganisation of cortical networks subserving memory retrieval. This research project will use brain imaging to understand how the brain reorganises working memory when it ages. It will provide a framework for understanding age-related memory decline in the brain, which will in turn provide key information for understanding memory difficulties in clinical populations.
Revealing how the human brain coordinates body movements for applications in health and technology. This project will extend the basic understanding about how the brain controls the movements of our bodies, and how it changes to allow us to adapt and refine our movements. This project will generate information that is critical for applications in the fields of health (e.g. rehabilitation) and technology (e.g. human-machine interfaces).
Investigating differences in decision-making ability in older adults. This project aims to investigate how healthy ageing impacts decision making and its associated neural circuits using computation modelling and neurogenetic methods. Decision-making is a fundamental cognitive ability, allowing us to choose the best course of action. This project will investigate the relationship between genes and decision-making performance across the adult lifespan. Expected outcomes include a deeper understan ....Investigating differences in decision-making ability in older adults. This project aims to investigate how healthy ageing impacts decision making and its associated neural circuits using computation modelling and neurogenetic methods. Decision-making is a fundamental cognitive ability, allowing us to choose the best course of action. This project will investigate the relationship between genes and decision-making performance across the adult lifespan. Expected outcomes include a deeper understanding of how decision-making evolves in healthy ageing, and a tool based on genetic scores and computational modelling to predict an individual's trajectory of cognitive function. This could help identify individuals who are at risk for cognitive decline, which could then inform better interventions.Read moreRead less
Effect of infant hand observation training on the early development of hand reaching and grasping in healthy infants and those with early brain damage. The best way to learn a new motor skill is to look at people who can already do it. But is this also true for infants? And, can we help infants with motor problems by teaching them how to do it? This project aims to answer these questions by studying training based on the observation of parent's actions by infants with and without brain damage.