Titanium Implants With Dual Micro- And Nano-Scale Topography For Electrically Stimulated Osteogenic And Antibacterial Functions
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
The long-term success of titanium implants in high-risk patients (especially diabetics) is compromised and the current project aims to address this by developing nano-engineered therapeutic titanium implants. With appropriate multi-scale roughness, enhanced bioactivity, local antibiotic release and electrical stimulation to further enhance these features, the project aims at patient outcomes, while allowing easy integration into the current implant market.
Novel Biocompatible Nickel-free Shape Memory Alloy Scaffolds For Biomedical Applications
Funder
National Health and Medical Research Council
Funding Amount
$530,789.00
Summary
The current project is aimed at the development of a new class of novel biocompatible nickel-free shape memory alloy (SMA) scaffolds for metallic implant applications. The new scaffolds possess the ability to exert a mechanical force on the surrounding bones, and stimulate new bone tissue ingrowth, due to their shape memory effect, superelasticity and bone-mimicking porous structure. The outcomes from this project will provide innovative implant materials.
Development And Evaluation Of Novel Antibacterial Coatings For The Prevention Of Infection On Biomedical Devices
Funder
National Health and Medical Research Council
Funding Amount
$284,402.00
Summary
This project aims to develop infection-resistant coatings that can be applied to a wide range of biomedical devices used in human health care. Novel antibacterial compounds from Australian plants (genus Eremophila) will be coated as thin layers onto model materials used for biomedical device fabrication, then onto real-life biomedical products and evaluated for ability to deter colonization by biofilm-forming human pathogenic bacteria.