Optimising Severe Malaria Treatment Using Pharmacokinetic-pharmacodynamic Modeling
Funder
National Health and Medical Research Council
Funding Amount
$218,490.00
Summary
Every year, severe malaria kills up to 800,000 people worldwide. To prevent death, a patient must be treated promptly and effectively. Children and adults vary in terms of their response to a malaria drug, and therefore may require a different dosing regimen. We will perform a rigorous analytical assessment of antimalarial drug concentration and efficacy data to determine dosing regimens. This will improve the treatment of severe malaria, and thereby, reduce malaria-related mortality.
A Randomised Controlled Trial Of Daily Antibacterial Mouthwash To Reduce Pharyngeal Gonorrhoea Among Men Who Have Sex With Men (MSM)
Funder
National Health and Medical Research Council
Funding Amount
$376,730.00
Summary
Gonorrhoea is a common sexually transmitted infection (STI) among gay men, and the throat is the commonest site of infection. There is early data to suggest Listerine mouthwash can be used to prevent gonorrhoea. Our study will examine whether men use Listerine every day will reduce the risk of gonorrhoea in the throat compared those who use another mouthwash product which does not have an effect on gonorrhoea.